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NCT06736626 · ClinicalTrials.gov registry record
The xDAPT External Validation Study
A clinical trial of Coronary Artery Disease and Percutaneous Coronary Intervention, sponsored by Icahn School of Medicine at Mount Sinai.
- Completed
- Registry status
- 30,000
- Enrollment target
- 1
- Study location
NCT06736626 is a study of Coronary Artery Disease and Percutaneous Coronary Intervention that has completed, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 30,000 participants, above the 1,150-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (2509% higher). The trial reports 1 study location across 1 state.
The verdict
NCT06736626, a study of Coronary Artery Disease and Percutaneous Coronary Intervention, has completed, sponsored by Icahn School of Medicine at Mount Sinai.
- COMPLETED
- Registry status
- 30,000 participants
- Enrollment target
- 1
- Study location
Study Summary
Dual antiplatelet therapy (DAPT) is routinely recommended after percutaneous coronary intervention (PCI) with drug-eluting stent (DES) implantation to prevent thrombotic complications. However, DAPT is also associated with an increased risk of bleeding, which may have a similar or even greater impact on prognosis compared to recurrent ischemic events. To balance these risks, individualized risk stratification at the time of PCI is crucial for determining the optimal DAPT composition and duration, aiming to reduce thrombotic risk while minimizing bleeding complications. For this purpose, an artificial intelligence-based risk stratification tool (xDAPT, Abbott) was introduced and demonstrated strong clinical performance in its development study (ClinicalTrials.gov identifier: NCT06089304). This analysis aims to evaluate the performance of xDAPT in a real-world cohort of patients who underwent PCI over the past decade at a large urban center (Mount Sinai Hospital, New York).
Conditions Studied
Interventions
- DEVICE Percutaneous coronary intervention
Study Locations (1)
New York
- Icahn School of Medicine at Mount Sinai - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30,000 participants |
| Start Date | 2012-01-01 |
| Est. Completion | 2024-12-01 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06736626
The ClinicalTrials.gov registry entry for NCT06736626 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 30,000 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 1,150-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (2509% higher). The listed sponsor is Icahn School of Medicine at Mount Sinai, which has 708 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Coronary Artery Disease appearing as the primary indexed condition, and to 1 intervention - of which Percutaneous coronary intervention is the first listed.
NCT06736626 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.
Frequently Asked Questions
What is clinical trial NCT06736626 about?
NCT06736626 is a clinical study titled "The xDAPT External Validation Study". Dual antiplatelet therapy (DAPT) is routinely recommended after percutaneous coronary intervention (PCI) with drug-eluting stent (DES) implantation to prevent thrombotic complications. However, DAPT is also associated with an increased risk of bleeding, which may have a similar or even greater impac...
What is the current status of trial NCT06736626?
This trial is currently completed. The enrollment target is 30,000 participants. The study started on 2012-01-01. Estimated completion is 2024-12-01.
What conditions does trial NCT06736626 study?
This clinical trial studies the following conditions: Coronary Artery Disease, Percutaneous Coronary Intervention.
What interventions are being tested in trial NCT06736626?
The interventions under investigation include: Percutaneous coronary intervention (DEVICE).
Who is sponsoring clinical trial NCT06736626?
This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06736626 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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