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Coronary Artery Disease clinical trials
57 of 220 indexed Coronary Artery Disease trials are currently recruiting.
220 US clinical trials · 57 currently recruiting
Coronary Artery Disease is the subject of 220 registered US clinical trials on ClinicalTrials.gov, 57 of them currently open to new participants. 42 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is University of Florida, running 17 of these trials.
The research picture
Coronary Artery Disease has 220 registered US clinical trials, 57 of them open to new participants right now, about 26% of the total.
- 57
- recruiting participants now
- 26%
- of trials open to enrollment
- 42
- in Phase 3–4 (later-stage)
- 17
- top sponsor: University of Florida
Active & Recent Trials
220 total, page 3 of 5
An Observational Study of Cholesterol in Coronary Arteries
Infraredx
NCT00831116
EVOLVE Short DAPT Study
Boston Scientific Corporation
NCT02605447
Genotype Information and Functional Testing Study
Scripps Health
NCT00992420
PIONEER III Trial to Assess Safety and Efficacy of the BuMA Supreme™ Drug Coated Coronary Stent in Patients With Coronary Disease
Sino Medical Sciences Technology
NCT03168776
The PLATINUM Clinical Trial to Assess the PROMUS Element Stent System for Treatment of De Novo Coronary Artery Lesions
Boston Scientific Corporation
NCT00823212
PLATINUM Diversity
Boston Scientific Corporation
NCT02240810
TAXUS IV-SR: Treatment of De Novo Coronary Disease Using a Single Paclitaxel-Eluting Stent
Boston Scientific Corporation
NCT00292474
TAXUS PERSEUS Workhorse
Boston Scientific Corporation
NCT00484315
Study of Sirolimus-Coated BX VELOCITY Balloon-Expandable Stent in Treatment of de Novo Native Coronary Artery Lesions (SIRIUS)
Cordis US
NCT00232765
Implementation of CYP2C19 Genotyping to Guide Antiplatelet Therapy
University of Florida
NCT02724319
Drug Eluting Stent Registry of Thrombosis
Medstar Health Research Institute
NCT00812552
Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina
Gilead Sciences
NCT01425359
Enhancing Recovery After Cardiac Surgery
University of California, Los Angeles
NCT00522717
ISCHEMIA-Chronic Kidney Disease Trial
NYU Langone Health
NCT01985360
Radial Artery Access With Ultrasound Trial
University of California, Irvine
NCT01605292
Vitamins in Nitrous Oxide Study
Washington University School of Medicine
NCT00655980
Safety and Efficacy Study Using ABT-335 (Investigational Drug) in Combination With Atorvastatin, to Study the Effects on Thickening of the Blood Vessel Wall in Patients With Abnormal Lipid (Fat) Levels in the Blood
AbbVie (prior sponsor, Abbott)
NCT00616772
Predictor of Advanced Subclinical Atherosclerosis
PreMD
NCT00245284
Retrospective Experience Of CIED Implantation
Elutia
NCT04351269
Coronary Obstruction Detection by Molecular Personalized Gene Expression (Corus CAD or ASGES)
CardioDx
NCT01117506
Role of Podocan and Wnt Pathway Regulatory Molecules in Coronary Artery Disease
Jennifer Victory, RN, CCRC
NCT02807714
Gadobutrol / Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)
Bayer
NCT01890434
Improving Adherence to Post PCI Antiplatelet Therapy in Minority Populations
University of Miami
NCT01651208
OPTIMIZE PCI: Multicenter Randomized Trial of OCT Compared to IVUS and Angiography to Guide Coronary Stent Implantation
Abbott Medical Devices
NCT02471586
Enhancing Cardiac Rehabilitation Through Behavioral Nudges
Denver Health and Hospital Authority
NCT03834155
Disrupt CAD III With the Shockwave Coronary IVL System
Shockwave Medical
NCT03595176
Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)
Bayer
NCT01890421
Observational Study of OCT in a Patients Undergoing FFR
Abbott Medical Devices
NCT01663896
Restore EF Observational Study
Abiomed
NCT04648306
Stress Echocardiography and Heart Computed Tomography (CT) Scan in Emergency Department Patients With Chest Pain
Montefiore Medical Center
NCT01384448
The Health Access and Recovery Peer Program
Emory University
NCT01725815
GUARD-AKI: Validation of AKI-Sapere in Cardiac Surgery Patients
Sapere Bio
NCT03635606
Hemostasis With QuikClot® Radial® Pad Versus TR Band® After Transradial Artery Access
Memorial Healthcare System
NCT03535597
Periprocedural Glycemic Control in Patients Undergoing Coronary Angiography
NYU Langone Health
NCT01419652
Fractional Flow Reserve and Intravascular Ultrasound RelationShip STudy
Volcano Corporation
NCT01153555
Targeting Inflammation Using Salsalate in CardioVascular Disease
Joslin Diabetes Center
NCT00624923
Frequency Analysis of Coronary Artery Disease
University of Minnesota
NCT01043237
The OMEGA Clinical Trial
Boston Scientific Corporation
NCT01419171
COBRA PZF™ Coronary Stent for Early Healing, Thrombus Inhibition, Endothelialization and Avoiding Long-Term DAPT
CeloNova BioSciences
NCT01925794
Evaluating a Low-Literacy Discharge Medication Education Tool
University of California, Los Angeles
NCT00408733
Anti-inflammatory Effects of Colchicine in PCI
NYU Langone Health
NCT01709981
MARS - Monitored Atherosclerosis Regression Study
Merck Sharp & Dohme
NCT00116870
Same Day Discharge (SDD) After Implantable Cardioverter Defibrillator (ICD) Implant
Abbott Medical Devices
NCT01993862
Clinical Investigation for Safety and Efficacy Study of CELT ACD (Arterial ClosureDevice)
Vasorum
NCT01600482
Exercise Cardiac Magnetic Resonance Imaging Accuracy for Cardiovascular Stress Testing
Ohio State University
NCT01592565
The Platelet Aggregation After tiCagrelor Inhibition and FentanYl Trial (PACIFY)
Johns Hopkins University
NCT02683707
Non-Invasive EndoPAT Increases Diagnostic Yield of CAD by Coronary Angiography
Mayo Clinic
NCT01581671
Analysis of Surface EKG Signals to Identify Myocardial Dysfunction in Patients at Risk for Coronary Artery Disease
Icahn School of Medicine at Mount Sinai
NCT02560168
Determinants of Cardiac Risk Factor Modification in Latinos With Coronary Artery Disease
Weill Medical College of Cornell University
NCT00248859
WARRIOR Ancillary Study for CCTA Analysis
Cedars-Sinai Medical Center
NCT05035056
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 9 |
| Phase 3 | 17 |
| Phase 4 | 25 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Coronary Artery Disease Trial Landscape
220 indexed Coronary Artery Disease studies · 57 recruiting (26%).
Phase mix: 42 late (III/IV) vs 15 early (I/II).
Top sponsor: University of Florida (17 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Coronary Artery Disease?
PlainTrial tracks 220 US clinical trials for Coronary Artery Disease, of which 57 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Coronary Artery Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.