Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03066050 · ClinicalTrials.gov registry record

Long Term Follow Up for CTSN Mitral Valve Repair Studies

A clinical trial of Coronary Artery Disease and Mitral Valve Insufficiency, sponsored by Icahn School of Medicine at Mount Sinai.

Active
Registry status
368
Enrollment target
20
Study locations

NCT03066050: Active study of Coronary Artery Disease and Mitral Valve Insufficiency, sponsored by Icahn School of Medicine at Mount Sinai.

NCT03066050 is a study of Coronary Artery Disease and Mitral Valve Insufficiency that is active but no longer recruiting, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 368 participants, below the 1,285-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (71% lower). The trial reports 20 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03066050, a study of Coronary Artery Disease and Mitral Valve Insufficiency, is active but no longer recruiting, sponsored by Icahn School of Medicine at Mount Sinai.

ACTIVE NOT RECRUITING
Registry status
368 participants
Enrollment target
20
Study locations

Study Summary

This study is a continuation of two previous studies --- the Severe Ischemic Mitral Regurgitation (SMR) Trial (NCT00807040) and the Moderate Ischemic Mitral regurgitation (MMR) Trial (NCT00806988) --- to learn more about patients' health 5-10 years after their mitral valve surgeries. The investigators will collect long-term health information on SMR and MMR trial participants using electronic medical records, patient and/or family input, public records, and healthcare- and vital status-related databases.

Primary Outcome

All-cause mortality will be assessed.

Interventions

  • OTHER MV Repair
  • OTHER MV Replacement
  • OTHER CABG

Study Locations (20)

North Carolina

  • Mission Hospital - Asheville
  • Duke University - Durham
  • East Carolina Heart Institute - Greenville

Ontario

  • Sunnybrook Health Science Centre - Toronto
  • Saint Michael's Hospital - Toronto
  • Toronto General Hospital - Toronto

Maryland

  • University of Maryland - Baltimore
  • Suburban Hospital - Bethesda

New York

  • Columbia University Medical Center - New York
  • Montefiore Einstein Heart Center - The Bronx

Ohio

  • Cleveland Clinic Foundation - Cleveland
  • Ohio State University - Columbus

Virginia

  • University of Virginia Health Systems - Charlottesville
  • Inova Heart and Vascular Institute - Falls Church

California

  • University of Southern California - Los Angeles

Georgia

  • Emory University - Atlanta

Trial Details

FieldValue
Enrollment Target 368 participants
Start Date 2017-05-03
Est. Completion 2027-07-31

What the registry record for NCT03066050 still lists

NCT03066050 is an observational study that tracks outcomes without assigning an intervention. The registered 368 participants enrollment target is mid-sized for trials with a published cap, below the 1,285-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (71% lower).

The record links to 2 conditions, with Coronary Artery Disease appearing as the primary indexed condition, and to 3 interventions - of which MV Repair is the first listed.

NCT03066050 names 20 study sites across 12 states, led by North Carolina, Ontario, Maryland.

Frequently Asked Questions

What is clinical trial NCT03066050 about?

NCT03066050 is a clinical study titled "Long Term Follow Up for CTSN Mitral Valve Repair Studies". This study is a continuation of two previous studies --- the Severe Ischemic Mitral Regurgitation (SMR) Trial (NCT00807040) and the Moderate Ischemic Mitral regurgitation (MMR) Trial (NCT00806988) --- to learn more about patients' health 5-10 years after their mitral valve surgeries. The investigato...

What is the current status of trial NCT03066050?

This trial is currently active not recruiting. The enrollment target is 368 participants. The study started on 2017-05-03. Estimated completion is 2027-07-31.

What conditions does trial NCT03066050 study?

This clinical trial studies the following conditions: Coronary Artery Disease, Mitral Valve Insufficiency.

What interventions are being tested in trial NCT03066050?

The interventions under investigation include: MV Repair (OTHER), MV Replacement (OTHER), CABG (OTHER).

Who is sponsoring clinical trial NCT03066050?

This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03066050 being conducted?

This trial has 20 study locations across California, Georgia, Maryland, Massachusetts, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Coronary Artery Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03066050's enrollment target sits among peer trials

368 93rd of 219 higher than 127 of 219 other Coronary Artery Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Coronary Artery Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT04675476 · 368 participants · NA

    A Patient and Provider Intervention to Address Health Disparities in Lung Cancer Screening

  • NCT05215353 · 368 participants · Phase 4

    A Study Comparing Music Therapy and Cognitive Behavioral Therapy for Anxiety in Cancer Survivors

  • NCT06182397 · 368 participants · NA

    Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease

  • NCT06629610 · 368 participants · NA

    Diet and Active Lifestyle - Yuuyaraq (The Yup'ik Way of Life)

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03066050, the US trial registry maintained by the National Library of Medicine. NCT03066050 (mid enrollment · wide site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.