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NCT06181240 · ClinicalTrials.gov registry record · NA
Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE)
A NA study of Coronary Artery Disease and Coronary Artery Calcification, sponsored by Bolt Medical.
- Active
- Registry status
- NA
- Development phase
- 420
- Enrollment target
- 20
- Study locations
NCT06181240: Active NA study of Coronary Artery Disease and Coronary Artery Calcification, sponsored by Bolt Medical.
NCT06181240 is a NA study of Coronary Artery Disease and Coronary Artery Calcification that is active but no longer recruiting, run by Bolt Medical. The registered enrollment target is 420 participants, below the 1,285-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (67% lower). The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06181240, a NA study of Coronary Artery Disease and Coronary Artery Calcification, is active but no longer recruiting, sponsored by Bolt Medical.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 420 participants
- Enrollment target
- 20
- Study locations
Study Summary
The FRACTURE Trial is a prospective, non-randomized, single-arm, multicenter, interventional study in US and international centers.
Primary Outcome
Freedom from major adverse cardiac events (MACE) within 30 days following the index procedure.
Conditions Studied
Interventions
- DEVICE Intravascular lithotripsy
Study Locations (20)
California
- Scripps Health - La Jolla
- Cedars-Sinai Heart Institute - Los Angeles
- Riverside Community Hospital - Riverside
- Southern California Permanente Medical Gp. / Kaiser Permanente - San Diego
- Los Robles Hospital & Medical Center - Thousand Oaks
Florida
- Nova Clinical Research Centers/Manatee Memorial Hospital - Bradenton
- The Cardiac & Vascular Institute - Gainesville
- HCA FL Memorial Hospital - Jacksonville
- HCA Florida Largo Hospital - Largo
Georgia
- Northeast Georgia Medical Center - Gainesville
- Wellstar Research Institute - Hiram
Massachusetts
- Brigham and Women's Hospital - Boston
- Massachusetts General Hospital - Boston
Colorado
- Medical Center of the Rockies - Loveland
Michigan
- Trinity Health Michigan Heart - Ypsilanti
Minnesota
- Metropolitan Heart and Vascular Institute - Coon Rapids
Mississippi
- North Mississippi Medical Center - Tupelo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 420 participants |
| Start Date | 2024-01-19 |
| Est. Completion | 2028-03-20 |
| Phase | NA |
What the registry record for NCT06181240 still lists
NCT06181240 is an interventional study that assigns participants to a tested intervention. The registered 420 participants enrollment target is mid-sized for trials with a published cap, below the 1,285-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (67% lower).
The record links to 2 conditions, with Coronary Artery Disease appearing as the primary indexed condition, and to 1 intervention - of which Intravascular lithotripsy is the first listed.
NCT06181240 names 20 study sites across 11 states, led by California, Florida, Georgia.
Frequently Asked Questions
What is clinical trial NCT06181240 about?
NCT06181240 is a clinical study titled "Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE)". The FRACTURE Trial is a prospective, non-randomized, single-arm, multicenter, interventional study in US and international centers.
What is the current status of trial NCT06181240?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 420 participants. The study started on 2024-01-19. Estimated completion is 2028-03-20.
What conditions does trial NCT06181240 study?
This clinical trial studies the following conditions: Coronary Artery Disease, Coronary Artery Calcification.
What interventions are being tested in trial NCT06181240?
The interventions under investigation include: Intravascular lithotripsy (DEVICE).
Who is sponsoring clinical trial NCT06181240?
This trial is sponsored by Bolt Medical, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06181240 being conducted?
This trial has 20 study locations across California, Colorado, Florida, Georgia, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Coronary Artery Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06181240's enrollment target sits among peer trials
420 85th of 219 higher than 135 of 219 other Coronary Artery Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Coronary Artery Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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