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COMPLETED

Inclusive Invasive Physiological Assessment in Angina Syndromes Registry

NCT04485234 · View on ClinicalTrials.gov ↗

Study Summary

This study evaluates the prognostic value and potential therapeutic impact of combined pressure and flow measurements in the evaluation of epicardial coronary stenosis and microvascular function.

Interventions

  • DIAGNOSTIC_TEST Resting distal coronary to aortic pressure ratio, Fractional flow reserve, Coronary Flow Reserve, Microvascular resistance

Study Locations (12)

Other

  • Aarhus University Hospital — Aarhus
  • Catholic University of the Sacred Heart — Roma
  • Gifu Heart Center — Gifu
  • Toda Central General Hospital — Toda
  • Tsuchiura Kyodo General Hospital — Tsuchiura
  • Amsterdam UMC - location AMC — Amsterdam
  • Tergooi — Blaricum
  • Amphia Hospital — Breda
  • Samsung Medical Center — Seoul
  • Seoul National University Hospital — Seoul
  • Hospital Clinico San Carlos — Madrid

Ohio

  • Cincinnati University Medical Center — Cincinnati

Trial Details

FieldValue
Enrollment Target 2,322 participants
Start Date 2019-06-01
Est. Completion 2021-03-25

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04485234

The ClinicalTrials.gov registry entry for NCT04485234 describes a study currently listed as completed. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 2,322 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), which has 33 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Coronary Artery Disease appearing as the primary indexed condition, and to 1 intervention — of which Resting distal coronary to aortic pressure ratio, Fractional flow reserve, Coronary Flow Reserve, Microvascular resistance is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04485234 reports 12 study locations spanning 2 distinct geographic areas — top geographies include Other, Ohio. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04485234 about?

NCT04485234 is a clinical study titled "Inclusive Invasive Physiological Assessment in Angina Syndromes Registry". This study evaluates the prognostic value and potential therapeutic impact of combined pressure and flow measurements in the evaluation of epicardial coronary stenosis and microvascular function.

What is the current status of trial NCT04485234?

This trial is currently completed. The enrollment target is 2,322 participants. The study started on 2019-06-01. Estimated completion is 2021-03-25.

What conditions does trial NCT04485234 study?

This clinical trial studies the following conditions: Coronary Artery Disease, Microvascular Coronary Artery Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04485234?

The interventions under investigation include: Resting distal coronary to aortic pressure ratio, Fractional flow reserve, Coronary Flow Reserve, Microvascular resistance (DIAGNOSTIC_TEST). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04485234?

This trial is sponsored by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), which has 33 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04485234 being conducted?

This trial has 12 study locations across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial