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NCT01399632 · ClinicalTrials.gov registry record · NA
Dietary Fat and High-Density Lipoprotein (HDL) Metabolism-Effect of Carbohydrate and Fat Intake
A NA study of Cardiovascular Diseases and Overweight, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- NA
- Development phase
- 21
- Enrollment target
- 1
- Study location
NCT01399632: Completed NA study of Cardiovascular Diseases and Overweight, sponsored by Brigham and Women's Hospital.
NCT01399632 is a NA study of Cardiovascular Diseases and Overweight that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 21 participants, below the 26,974-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01399632, a NA study of Cardiovascular Diseases and Overweight, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 21 participants
- Enrollment target
- 1
- Study location
Study Summary
Generally, people with low levels of high-density lipoprotein (HDL) in blood are more likely to get heart disease than those who have normal or high levels. Dietary fat, whether the harmful type (saturated) or beneficial type (unsaturated) raises HDL levels. Dietary carbohydrate lowers HDL. The investigators are doing this research study to find out why the amount of HDL in a person's blood is affected by dietary unsaturated fat and carbohydrate. The investigators will trace the ability of the HDL in a person's blood to take up cholesterol, get bigger, and then leave the blood by passing into the liver. The investigators want to know if dietary unsaturated fat improves the ability of HDL to do this compared to dietary carbohydrate.
Primary Outcome
To determine how dietary unsaturated fat when it replaces carbohydrate affects HDL metabolism.
Conditions Studied
Interventions
- BEHAVIORAL Low Fat and High Carbohydrate Diet
- BEHAVIORAL High Fat and Low Carbohydrate Diet
Study Locations (1)
Massachusetts
- Harvard T. H. Chan School of Public Health - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2010-08 |
| Est. Completion | 2013-12 |
| Phase | NA |
What the finished NCT01399632 record still lists
NCT01399632 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 26,974-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Cardiovascular Diseases appearing as the primary indexed condition, and to 2 interventions - of which Low Fat and High Carbohydrate Diet is the first listed.
NCT01399632 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT01399632 about?
NCT01399632 is a clinical study titled "Dietary Fat and High-Density Lipoprotein (HDL) Metabolism-Effect of Carbohydrate and Fat Intake". Generally, people with low levels of high-density lipoprotein (HDL) in blood are more likely to get heart disease than those who have normal or high levels. Dietary fat, whether the harmful type (saturated) or beneficial type (unsaturated) raises HDL levels. Dietary carbohydrate lowers HDL. The inve...
What is the current status of trial NCT01399632?
This trial is currently completed. It is a NA study. The enrollment target is 21 participants. The study started on 2010-08. Estimated completion is 2013-12.
What conditions does trial NCT01399632 study?
This clinical trial studies the following conditions: Cardiovascular Diseases, Overweight.
What interventions are being tested in trial NCT01399632?
The interventions under investigation include: Low Fat and High Carbohydrate Diet (BEHAVIORAL), High Fat and Low Carbohydrate Diet (BEHAVIORAL).
Who is sponsoring clinical trial NCT01399632?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01399632 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiovascular Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01399632's enrollment target sits among peer trials
21 279th of 300 higher than 20 of 300 other Cardiovascular Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiovascular Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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