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NCT03646370 · ClinicalTrials.gov registry record
Assessing Virologic Success and Metabolic Changes in Patients Switching From a TDF to TAF Containing Antiretroviral Therapy Regimen
A clinical trial of Cardiovascular Diseases and Metabolic Syndrome, sponsored by Thomas Jefferson University.
- Completed
- Registry status
- 110
- Enrollment target
- 1
- Study location
NCT03646370 is a study of Cardiovascular Diseases and Metabolic Syndrome that has completed, run by Thomas Jefferson University. The registered enrollment target is 110 participants, below the 26,974-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.
The verdict
NCT03646370, a study of Cardiovascular Diseases and Metabolic Syndrome, has completed, sponsored by Thomas Jefferson University.
- COMPLETED
- Registry status
- 110 participants
- Enrollment target
- 1
- Study location
Study Summary
Switching patients with HIV infection from tenofovir disoproxil fumarate (TDF) to a tenofovir alafenamide (TAF) based drug regimen can provide many safety benefits including preserving bone mineral density and kidney function. This study will examine metabolic changes that patients may encounter due to the switch in medication regimens and the maintenance of viral suppression.
Conditions Studied
Interventions
- DRUG Tenofovir Alafenamide
Study Locations (1)
Pennsylvania
- Thomas Jeffeson University - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 110 participants |
| Start Date | 2018-07-25 |
| Est. Completion | 2019-07-24 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03646370
The ClinicalTrials.gov registry entry for NCT03646370 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 110 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 26,974-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (100% lower). The listed sponsor is Thomas Jefferson University, which has 292 total studies on file at ClinicalTrials.gov.
The record links to 6 conditions, with Cardiovascular Diseases appearing as the primary indexed condition, and to 1 intervention - of which Tenofovir Alafenamide is the first listed.
NCT03646370 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT03646370 about?
NCT03646370 is a clinical study titled "Assessing Virologic Success and Metabolic Changes in Patients Switching From a TDF to TAF Containing Antiretroviral Therapy Regimen". Switching patients with HIV infection from tenofovir disoproxil fumarate (TDF) to a tenofovir alafenamide (TAF) based drug regimen can provide many safety benefits including preserving bone mineral density and kidney function. This study will examine metabolic changes that patients may encounter due...
What is the current status of trial NCT03646370?
This trial is currently completed. The enrollment target is 110 participants. The study started on 2018-07-25. Estimated completion is 2019-07-24.
What conditions does trial NCT03646370 study?
This clinical trial studies the following conditions: Cardiovascular Diseases, Metabolic Syndrome, HIV-1-infection, Hyperglycemia, Weight Gain.
What interventions are being tested in trial NCT03646370?
The interventions under investigation include: Tenofovir Alafenamide (DRUG).
Who is sponsoring clinical trial NCT03646370?
This trial is sponsored by Thomas Jefferson University, which has 292 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03646370 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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