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ClinicalTrials.gov 10 recruiting now official registry

Cardiomyopathy clinical trials

Every US clinical trial registered for Cardiomyopathy — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

26 US clinical trials · 10 currently recruiting

The research picture

Cardiomyopathy has 26 registered US clinical trials, 10 of them open to new participants right now — about 38% of the total.

10
recruiting participants now
38%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
2
top sponsor: Medtronic Cardiac Rhythm and Heart Failure

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 5,000 participants

Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System

National Heart, Lung, and Blood Institute (NHLBI)

NCT01143454

RECRUITING Phase 4 2,000 participants

Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator

University of Rochester

NCT06964464

RECRUITING 2,000 participants

Genetics of Cardiovascular and Neuromuscular Disease

University of Chicago

NCT00138931

RECRUITING 200 participants

Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy

Tenaya Therapeutics

NCT05112237

RECRUITING 200 participants

TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer

Mayo Clinic

NCT05507879

RECRUITING NA 171 participants

Molecular Imaging of Primary Amyloid Cardiomyopathy

Brigham and Women's Hospital

NCT02641145

RECRUITING Phase 1 72 participants

Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by Anthracyclines

M.D. Anderson Cancer Center

NCT02962661

RECRUITING 65 participants

Clinical Course Of Disease In Participants With FA-CM

Lexeo Therapeutics

NCT06865482

RECRUITING 50 participants

Impella Reverse Remodeling in End-Stage Heart Failure

Columbia University

NCT06800716

RECRUITING NA 12 participants

Large Language Models To Improve the Quality of Care of Cardiology Patients

Stanford University

NCT06935253

COMPLETED 1,999 participants

InSync Model 8040 (InSync) and InSync III Model 8042 (InSync III) Registry

Medtronic Cardiac Rhythm and Heart Failure

NCT00273182

COMPLETED 450 participants

PROSPECT: Predictors of Response to Cardiac Re-Synchronization Therapy

Medtronic Cardiac Rhythm and Heart Failure

NCT00253357

COMPLETED NA 438 participants

Telephone Intervention in Heart Failure Patients

US Department of Veterans Affairs

NCT00057057

COMPLETED 373 participants

Study Looking at the Recovery of New Onset Cardiomyopathy

University of Pittsburgh

NCT00575211

COMPLETED 325 participants

Patients' Long-Term Survival of Obstructive Hypertrophic Cardiomyopathy (HCM)

National Heart, Lung, and Blood Institute (NHLBI)

NCT04603521

COMPLETED 178 participants

Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage

National Institute of Environmental Health Sciences (NIEHS)

NCT01143519

COMPLETED 70 participants

Speckle Tracking in Pediatric Patients

Emory University

NCT00489957

COMPLETED NA 60 participants

Evaluating Myocardial Injury for Defibrillation Threshold Testing Methods for ICD Implantation

University of California, San Diego

NCT02111993

COMPLETED Phase 4 55 participants

Mechanisms of Improvement With Beta-Blocker Treatment in Heart Failure

Michael E. DeBakey VA Medical Center

NCT01261065

COMPLETED NA 50 participants

RF Surgical Sponge-Detecting System on the Function of Pacemakers and Implantable Cardioverter Defibrillators

University of California, San Diego

NCT02111980

COMPLETED Phase 3 40 participants

Biventricular Pacing In Patients With Left Ventricular Dysfunction After Cardiovascular Surgery

Corewell Health East

NCT00321295

COMPLETED 36 participants

Ventricular Arrhythmias in Uremic Cardiomyopathy

Northwell Health

NCT01856400

COMPLETED Phase 2 30 participants

The Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in Patients Undergoing LVAD Implantation

Deborah Ascheim

NCT01442129

COMPLETED NA 22 participants

Resistance and Aerobic Exercise for Subclinical Anthracycline Cardiomyopathy

St. Jude Children's Research Hospital

NCT01071473

COMPLETED Phase 1 20 participants

Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Systolic Cardiomyopathy (Aim2)

Mayo Clinic

NCT01970176

COMPLETED Phase 1 7 participants

Bone Marrow Derived Mesenchymal Stem Cells in Improving Heart Function in Patients With Heart Failure Caused by Anthracyclines

M.D. Anderson Cancer Center

NCT02408432

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 1
Phase 3 1
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Cardiomyopathy Trial Landscape

ClinicalTrials.gov lists 26 US studies indexed under Cardiomyopathy, and 10 of those are currently open to recruitment — roughly 38% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Cardiomyopathy shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Cardiomyopathy is led by Medtronic Cardiac Rhythm and Heart Failure with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 26 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Cardiomyopathy?

PlainTrial tracks 26 US clinical trials for Cardiomyopathy, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Cardiomyopathy?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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