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Cardiomyopathy clinical trials
Every US clinical trial registered for Cardiomyopathy — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
26 US clinical trials · 10 currently recruiting
The research picture
Cardiomyopathy has 26 registered US clinical trials, 10 of them open to new participants right now — about 38% of the total.
- 10
- recruiting participants now
- 38%
- of trials open to enrollment
- 3
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Medtronic Cardiac Rhythm and Heart Failure
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System
National Heart, Lung, and Blood Institute (NHLBI)
NCT01143454
Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator
University of Rochester
NCT06964464
Genetics of Cardiovascular and Neuromuscular Disease
University of Chicago
NCT00138931
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy
Tenaya Therapeutics
NCT05112237
TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer
Mayo Clinic
NCT05507879
Molecular Imaging of Primary Amyloid Cardiomyopathy
Brigham and Women's Hospital
NCT02641145
Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by Anthracyclines
M.D. Anderson Cancer Center
NCT02962661
Clinical Course Of Disease In Participants With FA-CM
Lexeo Therapeutics
NCT06865482
Impella Reverse Remodeling in End-Stage Heart Failure
Columbia University
NCT06800716
Large Language Models To Improve the Quality of Care of Cardiology Patients
Stanford University
NCT06935253
InSync Model 8040 (InSync) and InSync III Model 8042 (InSync III) Registry
Medtronic Cardiac Rhythm and Heart Failure
NCT00273182
PROSPECT: Predictors of Response to Cardiac Re-Synchronization Therapy
Medtronic Cardiac Rhythm and Heart Failure
NCT00253357
Telephone Intervention in Heart Failure Patients
US Department of Veterans Affairs
NCT00057057
Study Looking at the Recovery of New Onset Cardiomyopathy
University of Pittsburgh
NCT00575211
Patients' Long-Term Survival of Obstructive Hypertrophic Cardiomyopathy (HCM)
National Heart, Lung, and Blood Institute (NHLBI)
NCT04603521
Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage
National Institute of Environmental Health Sciences (NIEHS)
NCT01143519
Speckle Tracking in Pediatric Patients
Emory University
NCT00489957
Evaluating Myocardial Injury for Defibrillation Threshold Testing Methods for ICD Implantation
University of California, San Diego
NCT02111993
Mechanisms of Improvement With Beta-Blocker Treatment in Heart Failure
Michael E. DeBakey VA Medical Center
NCT01261065
RF Surgical Sponge-Detecting System on the Function of Pacemakers and Implantable Cardioverter Defibrillators
University of California, San Diego
NCT02111980
Biventricular Pacing In Patients With Left Ventricular Dysfunction After Cardiovascular Surgery
Corewell Health East
NCT00321295
Ventricular Arrhythmias in Uremic Cardiomyopathy
Northwell Health
NCT01856400
The Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in Patients Undergoing LVAD Implantation
Deborah Ascheim
NCT01442129
Resistance and Aerobic Exercise for Subclinical Anthracycline Cardiomyopathy
St. Jude Children's Research Hospital
NCT01071473
Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Systolic Cardiomyopathy (Aim2)
Mayo Clinic
NCT01970176
Bone Marrow Derived Mesenchymal Stem Cells in Improving Heart Function in Patients With Heart Failure Caused by Anthracyclines
M.D. Anderson Cancer Center
NCT02408432
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 1 |
| Phase 3 | 1 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Cardiomyopathy Trial Landscape
ClinicalTrials.gov lists 26 US studies indexed under Cardiomyopathy, and 10 of those are currently open to recruitment — roughly 38% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Cardiomyopathy shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Cardiomyopathy is led by Medtronic Cardiac Rhythm and Heart Failure with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 26 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Cardiomyopathy?
PlainTrial tracks 26 US clinical trials for Cardiomyopathy, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Cardiomyopathy?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.