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NCT06800716 · ClinicalTrials.gov registry record
Impella Reverse Remodeling in End-Stage Heart Failure
A clinical trial of Heart Failure and Cardiomyopathy, sponsored by Columbia University.
- Recruiting
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT06800716: Recruiting study of Heart Failure and Cardiomyopathy, sponsored by Columbia University.
NCT06800716 is a study of Heart Failure and Cardiomyopathy that is actively recruiting participants, run by Columbia University. The registered enrollment target is 50 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06800716, a study of Heart Failure and Cardiomyopathy, is actively recruiting participants, sponsored by Columbia University.
- RECRUITING
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
This observational study is being done to learn more about heart attack recovery in patients supported with the Impella 5.5 left ventricular assist device (LVAD) as part of their standard of care. There are three stages in this study: screening, treatment and post treatment. There will be two phases of enrollment: First phase will enroll 10 patients; second phase will enroll an additional 40 patients. Approximately 50 participants will take part in the study at Columbia University Irving Medical Center. Participation in this research is expected to last approximately 14 months. This time estimate includes a screening period for about 1- 3 days, treatment period of 40 days and post treatment follow-up period for 1 year. Data will be collected through 1- year after heart transplant. Clinical data (medical history, vital signs, laboratory assessments) from medical records, to perform functional testing, and to obtain blood and discarded heart tissue fromfor the purpose of this research study. Participants will be asked to share their records for echocardiography, right heart catheterization, laboratory data and clinical information. Participants are required to complete an assessment a 6-minute walk, and hand grip strength test.
Primary Outcome
A change in echocardiographic index will be evaluated by measuring a change in LVEF before and after Impella support at minimal pump setting.
Conditions Studied
Study Locations (1)
New York
- Columbia University - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2024-12-04 |
| Est. Completion | 2027-11 |
What NCT06800716 shows while recruiting
NCT06800716 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with Heart Failure appearing as the primary indexed condition, and to 0 interventions.
NCT06800716 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT06800716 about?
NCT06800716 is a clinical study titled "Impella Reverse Remodeling in End-Stage Heart Failure". This observational study is being done to learn more about heart attack recovery in patients supported with the Impella 5.5 left ventricular assist device (LVAD) as part of their standard of care. There are three stages in this study: screening, treatment and post treatment. There will be two phases...
What is the current status of trial NCT06800716?
This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2024-12-04. Estimated completion is 2027-11.
What conditions does trial NCT06800716 study?
This clinical trial studies the following conditions: Heart Failure, Cardiomyopathy.
Who is sponsoring clinical trial NCT06800716?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06800716 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06800716's enrollment target sits among peer trials
50 281st of 397 higher than 106 of 397 other Heart Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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