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NCT05112237 · ClinicalTrials.gov registry record
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy
A clinical trial of Cardiomyopathy, sponsored by Tenaya Therapeutics.
- Recruiting
- Registry status
- 200
- Enrollment target
- 20
- Study locations
NCT05112237: Recruiting study of Cardiomyopathy, sponsored by Tenaya Therapeutics.
NCT05112237 is a study of Cardiomyopathy that is actively recruiting participants, run by Tenaya Therapeutics. The registered enrollment target is 200 participants, below the 549-participant average among 25 other Cardiomyopathy trials with a reported enrollment target (64% lower). The trial reports 20 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05112237, a study of Cardiomyopathy, is actively recruiting participants, sponsored by Tenaya Therapeutics.
- RECRUITING
- Registry status
- 200 participants
- Enrollment target
- 20
- Study locations
Study Summary
The objective of this study is to collect information on patients with cardiomyopathy (CM) due to mutations in the MYBPC3 gene, to evaluate their disease course, burden of illness, risk factors for this disease, and the quality of life (QoL). This study will also collect information on treatments, procedures and outcome in infants and children up to 18 yrs who have this mutation.
Conditions Studied
Study Locations (20)
New York
- Cohen Children's Medical Center - Lake Success
- Mount Sinai - New York
- Columbia University Irving Medical Center - New York
- Montefiore Medical Center, Albert Einstein College of Medicine - The Bronx
California
- Children's Hospital Los Angeles - Los Angeles
- University of California Davis Health - Sacramento
- Rady Children's Hospital - San Diego - San Diego
Ohio
- Cincinnati Children's Hospital Medical Center - Cincinnati
- Cleveland Clinic Main Campus - Cleveland
- DDC Clinic Center for Special Needs Children - Middlefield
Pennsylvania
- Cardiology Care for Children - Lancaster
- Children's Hospital of Philadelphia - Philadelphia
- University of Pittsburgh Medical Center - Children's Hospital of Pittsburgh - Pittsburgh
Missouri
- Children's Mercy Hospital Kansas - Kansas City
- St. Louis Children's Hospital - St Louis
Arkansas
- Arkansas Children's Hospital - Little Rock
Colorado
- University of Colorado Hospital - Anschutz Medical Campus - Aurora
Delaware
- Nemours Alfred I. Dupont Hospital for Children - Wilmington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2021-11-01 |
| Est. Completion | 2028-06 |
What NCT05112237 shows while recruiting
NCT05112237 is an observational study that tracks outcomes without assigning an intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 549-participant average among 25 other Cardiomyopathy trials with a reported enrollment target (64% lower).
The record links to 1 condition, with Cardiomyopathy appearing as the primary indexed condition, and to 0 interventions.
NCT05112237 names 20 study sites across 10 states, led by New York, California, Ohio.
Frequently Asked Questions
What is clinical trial NCT05112237 about?
NCT05112237 is a clinical study titled "Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy". The objective of this study is to collect information on patients with cardiomyopathy (CM) due to mutations in the MYBPC3 gene, to evaluate their disease course, burden of illness, risk factors for this disease, and the quality of life (QoL). This study will also collect information on treatments, p...
What is the current status of trial NCT05112237?
This trial is currently recruiting. The enrollment target is 200 participants. The study started on 2021-11-01. Estimated completion is 2028-06.
What conditions does trial NCT05112237 study?
This clinical trial studies the following conditions: Cardiomyopathy.
Who is sponsoring clinical trial NCT05112237?
This trial is sponsored by Tenaya Therapeutics, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05112237 being conducted?
This trial has 20 study locations across Arkansas, California, Colorado, Delaware, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiomyopathy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05112237's enrollment target sits among peer trials
200 9th of 25 higher than 16 of 25 other Cardiomyopathy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiomyopathy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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