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NCT01856400 · ClinicalTrials.gov registry record
Ventricular Arrhythmias in Uremic Cardiomyopathy
A clinical trial of Cardiomyopathy, sponsored by Northwell Health.
- Completed
- Registry status
- 36
- Enrollment target
- 1
- Study location
NCT01856400: Completed study of Cardiomyopathy, sponsored by Northwell Health.
NCT01856400 is a study of Cardiomyopathy that has completed, run by Northwell Health. The registered enrollment target is 36 participants, below the 555-participant average among 25 other Cardiomyopathy trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01856400, a study of Cardiomyopathy, has completed, sponsored by Northwell Health.
- COMPLETED
- Registry status
- 36 participants
- Enrollment target
- 1
- Study location
Study Summary
There is a certain gene called sarcoplasmic reticulum gene (SERCA2a), which is found in heart muscle. This gene is also found in blood vessels and skin tissue. When active this gene builds a crucial protein inside the heart muscle called SERCA2a protein. This is responsible for regulating calcium levels inside your heart muscle. When this gene is not activated, studies have shown that it can lead to abnormal electrical currents in the heart that can lead to death. The investigators are conducting this study to prove that SERCA2a gene is inactive in patients with kidney disease. Scientists found that patient at risk for abnormal electrical currents in the heart can be tested by what they called "microvolt Twave alternans." This is a very delicate machine much more sensitive than a regular electrocardiogram that you do at the cardiology office.
Primary Outcome
To assess the expression of SERCA2a gene expression in Uremic Cardiomyopathy patients to see if the degree of expression is implicated in ventricular arrythmias
Conditions Studied
Study Locations (1)
New York
- Staten Island University Hospital - Staten Island
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2010-01 |
| Est. Completion | 2013-08 |
What the finished NCT01856400 record still lists
NCT01856400 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 555-participant average among 25 other Cardiomyopathy trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Cardiomyopathy appearing as the primary indexed condition, and to 0 interventions.
NCT01856400 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT01856400 about?
NCT01856400 is a clinical study titled "Ventricular Arrhythmias in Uremic Cardiomyopathy". There is a certain gene called sarcoplasmic reticulum gene (SERCA2a), which is found in heart muscle. This gene is also found in blood vessels and skin tissue. When active this gene builds a crucial protein inside the heart muscle called SERCA2a protein. This is responsible for regulating calcium le...
What is the current status of trial NCT01856400?
This trial is currently completed. The enrollment target is 36 participants. The study started on 2010-01. Estimated completion is 2013-08.
What conditions does trial NCT01856400 study?
This clinical trial studies the following conditions: Cardiomyopathy.
Who is sponsoring clinical trial NCT01856400?
This trial is sponsored by Northwell Health, which has 370 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01856400 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01856400's enrollment target sits among peer trials
36 21st of 25 higher than 5 of 25 other Cardiomyopathy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiomyopathy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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