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NCT00575211 · ClinicalTrials.gov registry record
Study Looking at the Recovery of New Onset Cardiomyopathy
A clinical trial of Cardiomyopathy, sponsored by University of Pittsburgh.
- Completed
- Registry status
- 373
- Enrollment target
- 16
- Study locations
NCT00575211: Completed study of Cardiomyopathy, sponsored by University of Pittsburgh.
NCT00575211 is a study of Cardiomyopathy that has completed, run by University of Pittsburgh. The registered enrollment target is 373 participants, below the 542-participant average among 25 other Cardiomyopathy trials with a reported enrollment target (31% lower). The trial reports 16 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00575211, a study of Cardiomyopathy, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- 373 participants
- Enrollment target
- 16
- Study locations
Study Summary
This is a multi-center, prospective evaluation of left ventricular recovery on conventional therapy in patients with the recent onset of dilated cardiomyopathy. In some subjects with this disorder, the heart will recover significantly over the first year, while others will be left with a chronically weak heart. The proteins that help the heart recover are encoded by genes, which can differ markedly between individuals. The goal of the current study is to determine whether variation in these genes involved affect the probability that the heart will recover. We will also look at which genes are involved in inflammation and which ones are "turned on" (producing proteins) in circulating white blood cells.{These statements will only be added if the site has chosen to participate in RNA analysis}. In addition, this study will look at how levels of proteins in the blood, proteins called "cytokines' which control inflammation and proteins called "neurohormones" which are released when the heart weakens, affect the likelihood of recovery. Enrollment will take place at 15 centers. The goal is to enroll approximately 500 adult subjects (age 18 years or older, both men and women) over the course of approximately 48 months.
Conditions Studied
Study Locations (16)
Pennsylvania
- Milton S. Hershey Medical Center - Hershey
- Thomas Jefferson University - Philadelphia
- University of Pittsburgh Medical Center - Pittsburgh
Texas
- University of Texas Southwestern Medical Center - Dalls
- The Methodist Hospital - Houston
California
- University of California - Irvine - Orange
Florida
- University of Florida - Gainesville
Maryland
- Johns Hopkins University - Baltimore
Massachusetts
- Massachusetts General Hospital - Boston
Minnesota
- Mayo Clinic - Rochester
New Jersey
- Newark Beth Israel Medical Center - Newark
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 373 participants |
| Start Date | 2004-01 |
| Est. Completion | 2011-03 |
What the finished NCT00575211 record still lists
NCT00575211 is an observational study that tracks outcomes without assigning an intervention. The registered 373 participants enrollment target is mid-sized for trials with a published cap, below the 542-participant average among 25 other Cardiomyopathy trials with a reported enrollment target (31% lower).
The record links to 1 condition, with Cardiomyopathy appearing as the primary indexed condition, and to 0 interventions.
NCT00575211 lists 16 locations in 13 states (Pennsylvania, Texas, California).
Frequently Asked Questions
What is clinical trial NCT00575211 about?
NCT00575211 is a clinical study titled "Study Looking at the Recovery of New Onset Cardiomyopathy". This is a multi-center, prospective evaluation of left ventricular recovery on conventional therapy in patients with the recent onset of dilated cardiomyopathy. In some subjects with this disorder, the heart will recover significantly over the first year, while others will be left with a chronically...
What is the current status of trial NCT00575211?
This trial is currently completed. The enrollment target is 373 participants. The study started on 2004-01. Estimated completion is 2011-03.
What conditions does trial NCT00575211 study?
This clinical trial studies the following conditions: Cardiomyopathy.
Who is sponsoring clinical trial NCT00575211?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00575211 being conducted?
This trial has 16 study locations across California, Florida, Maryland, Massachusetts, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00575211's enrollment target sits among peer trials
373 7th of 25 higher than 19 of 25 other Cardiomyopathy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiomyopathy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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