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NCT00575211 · ClinicalTrials.gov registry record

Study Looking at the Recovery of New Onset Cardiomyopathy

A clinical trial of Cardiomyopathy, sponsored by University of Pittsburgh.

Completed
Registry status
373
Enrollment target
16
Study locations

NCT00575211 is a study of Cardiomyopathy that has completed, run by University of Pittsburgh. The registered enrollment target is 373 participants, below the 542-participant average among 25 other Cardiomyopathy trials with a reported enrollment target (31% lower). The trial reports 16 study locations across 13 states.

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The verdict

NCT00575211, a study of Cardiomyopathy, has completed, sponsored by University of Pittsburgh.

COMPLETED
Registry status
373 participants
Enrollment target
16
Study locations

Study Summary

This is a multi-center, prospective evaluation of left ventricular recovery on conventional therapy in patients with the recent onset of dilated cardiomyopathy. In some subjects with this disorder, the heart will recover significantly over the first year, while others will be left with a chronically weak heart. The proteins that help the heart recover are encoded by genes, which can differ markedly between individuals. The goal of the current study is to determine whether variation in these genes involved affect the probability that the heart will recover. We will also look at which genes are involved in inflammation and which ones are "turned on" (producing proteins) in circulating white blood cells.{These statements will only be added if the site has chosen to participate in RNA analysis}. In addition, this study will look at how levels of proteins in the blood, proteins called "cytokines' which control inflammation and proteins called "neurohormones" which are released when the heart weakens, affect the likelihood of recovery. Enrollment will take place at 15 centers. The goal is to enroll approximately 500 adult subjects (age 18 years or older, both men and women) over the course of approximately 48 months.

Conditions Studied

Cardiomyopathy

Study Locations (16)

Pennsylvania

  • Milton S. Hershey Medical Center - Hershey
  • Thomas Jefferson University - Philadelphia
  • University of Pittsburgh Medical Center - Pittsburgh

Texas

  • University of Texas Southwestern Medical Center - Dalls
  • The Methodist Hospital - Houston

California

  • University of California - Irvine - Orange

Florida

  • University of Florida - Gainesville

Maryland

  • Johns Hopkins University - Baltimore

Massachusetts

  • Massachusetts General Hospital - Boston

Minnesota

  • Mayo Clinic - Rochester

New Jersey

  • Newark Beth Israel Medical Center - Newark

Trial Details

FieldValue
Enrollment Target 373 participants
Start Date 2004-01
Est. Completion 2011-03

Sponsor

University of Pittsburgh

1,238 total trials

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What the Registry Record Tells You About NCT00575211

The ClinicalTrials.gov registry entry for NCT00575211 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 373 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 542-participant average among 25 other Cardiomyopathy trials with a reported enrollment target (31% lower). The listed sponsor is University of Pittsburgh, which has 1,238 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Cardiomyopathy appearing as the primary indexed condition, and to 0 interventions.

NCT00575211 reports 16 study locations spanning 13 distinct geographic areas - top geographies include Pennsylvania, Texas, California.

Frequently Asked Questions

What is clinical trial NCT00575211 about?

NCT00575211 is a clinical study titled "Study Looking at the Recovery of New Onset Cardiomyopathy". This is a multi-center, prospective evaluation of left ventricular recovery on conventional therapy in patients with the recent onset of dilated cardiomyopathy. In some subjects with this disorder, the heart will recover significantly over the first year, while others will be left with a chronically...

What is the current status of trial NCT00575211?

This trial is currently completed. The enrollment target is 373 participants. The study started on 2004-01. Estimated completion is 2011-03.

What conditions does trial NCT00575211 study?

This clinical trial studies the following conditions: Cardiomyopathy.

Who is sponsoring clinical trial NCT00575211?

This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00575211 being conducted?

This trial has 16 study locations across California, Florida, Maryland, Massachusetts, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.