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NCT01970176 · ClinicalTrials.gov registry record · Phase 1
Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Systolic Cardiomyopathy (Aim2)
A Phase 1 study of Renal Impairment and Cardiomyopathy, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT01970176: Completed Phase 1 study of Renal Impairment and Cardiomyopathy, sponsored by Mayo Clinic.
NCT01970176 is a Phase 1 study of Renal Impairment and Cardiomyopathy that has completed, run by Mayo Clinic. The registered enrollment target is 20 participants, below the 34-participant average among 32 other Renal Impairment trials with a reported enrollment target (41% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01970176, a Phase 1 study of Renal Impairment and Cardiomyopathy, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
To determine the effect of 12 weeks of chronic PDEV inhibition with Tadalafil versus placebo on basal cardiorenal and humoral function and on the integrated cardiorenal and humoral response to acute sodium loading in subjects with preclinical systolic dysfunction (PSD) and renal (kidney) dysfunction.
Primary Outcome
Change in total urinary sodium excretion as measured by MEq/min
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Tadalafil
Study Locations (1)
Minnesota
- Mayo Clinic - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2014-01-09 |
| Est. Completion | 2019-09 |
| Phase | Phase 1 |
What the finished NCT01970176 record still lists
NCT01970176 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 34-participant average among 32 other Renal Impairment trials with a reported enrollment target (41% lower).
The record links to 2 conditions, with Renal Impairment appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT01970176 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT01970176 about?
NCT01970176 is a clinical study titled "Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Systolic Cardiomyopathy (Aim2)". To determine the effect of 12 weeks of chronic PDEV inhibition with Tadalafil versus placebo on basal cardiorenal and humoral function and on the integrated cardiorenal and humoral response to acute sodium loading in subjects with preclinical systolic dysfunction (PSD) and renal (kidney) dysfunction...
What is the current status of trial NCT01970176?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2014-01-09. Estimated completion is 2019-09.
What conditions does trial NCT01970176 study?
This clinical trial studies the following conditions: Renal Impairment, Cardiomyopathy.
What interventions are being tested in trial NCT01970176?
The interventions under investigation include: Placebo (DRUG), Tadalafil (DRUG).
Who is sponsoring clinical trial NCT01970176?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01970176 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Renal Impairment
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01970176's enrollment target sits among peer trials
20 27th of 32 higher than 6 of 32 other Renal Impairment trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Renal Impairment trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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