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NCT05507879 · ClinicalTrials.gov registry record

TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer

A clinical trial of Breast Carcinoma and Congestive Heart Failure, sponsored by Mayo Clinic.

Recruiting
Registry status
200
Enrollment target
2
Study locations

NCT05507879 is a study of Breast Carcinoma and Congestive Heart Failure that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 200 participants, below the 769-participant average among 106 other Breast Carcinoma trials with a reported enrollment target (74% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT05507879, a study of Breast Carcinoma and Congestive Heart Failure, is actively recruiting participants, sponsored by Mayo Clinic.

RECRUITING
Registry status
200 participants
Enrollment target
2
Study locations

Study Summary

This study examines TRPC6 in predicting and preventing chemotherapy related cardiac toxicity and heart failure in patients with breast cancer. Cardiac toxicity, changes in heart function is a well-recognized complication of certain cancer related therapies. Understanding these changes may allow early intervention against therapy-related cardiac toxicity and also identify novel therapeutic targets to protect patient long-term cardiac health. Studying samples of blood from patients with breast cancer in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA), identify biomarkers related to cardiac toxicity, and prevent the development of therapy-induced cardiac toxicity in patients receiving chemotherapy.

Interventions

  • PROCEDURE Biospecimen Collection
  • OTHER Electronic Medical Record

Study Locations (2)

Florida

  • University of Florida - Gainesville
  • Mayo Clinic in Florida - Jacksonville

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2022-09-26
Est. Completion 2027-09-01

Sponsor

Mayo Clinic

2,844 total trials

What the Registry Record Tells You About NCT05507879

The ClinicalTrials.gov registry entry for NCT05507879 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 769-participant average among 106 other Breast Carcinoma trials with a reported enrollment target (74% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Breast Carcinoma appearing as the primary indexed condition, and to 2 interventions - of which Biospecimen Collection is the first listed.

NCT05507879 reports 2 study locations spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT05507879 about?

NCT05507879 is a clinical study titled "TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer". This study examines TRPC6 in predicting and preventing chemotherapy related cardiac toxicity and heart failure in patients with breast cancer. Cardiac toxicity, changes in heart function is a well-recognized complication of certain cancer related therapies. Understanding these changes may allow earl...

What is the current status of trial NCT05507879?

This trial is currently recruiting. The enrollment target is 200 participants. The study started on 2022-09-26. Estimated completion is 2027-09-01.

What conditions does trial NCT05507879 study?

This clinical trial studies the following conditions: Breast Carcinoma, Congestive Heart Failure, Cardiomyopathy.

What interventions are being tested in trial NCT05507879?

The interventions under investigation include: Biospecimen Collection (PROCEDURE), Electronic Medical Record (OTHER).

Who is sponsoring clinical trial NCT05507879?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05507879 being conducted?

This trial has 2 study locations across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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