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ClinicalTrials.gov 279 recruiting now early-phase tilt #6 of 28,707 conditions

Cancer: early-phase trial registry

279 of 621 indexed Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #6 of 28,707 conditions by registered trial count.

621 US clinical trials · 279 currently recruiting · #6 of 28,707 conditions by registered trial count

Cancer: 621 US clinical trials tracked, 279 recruiting.

Cancer is the subject of 621 registered US clinical trials on ClinicalTrials.gov, 279 of them currently open to new participants. 31 are in Phase 3-4 (later-stage) and 164 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 31 of these trials.

Enrollment posture brief

Registry condition cancer

OPEN 279 | RECR 45% | LATE 31 | EARLY 164 | RANK #6 | SPON 31

Nearest open-share peer: Duchenne Muscular Dystrophy (45% recruiting · 49 trials)

Cancer (this)45%Prostate Cancer36.7%Depression35.7%Hypertension32.2%HIV Infections9.1%
Open-enrollment share among volume-matched conditions near Cancer

Cancer lists 279 open slots (45% of 621 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Cancer is recruiting above its size-band peers.

    279 of 621 indexed trials (44.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Cancer trials is spread across many organizations.

    M.D. Anderson Cancer Center accounts for 31 of 621 trials (5%). 270 distinct sponsors appear on at least one study for this condition label.

  3. Typical Cancer enrolment sits around 108 participants.

    Median target enrolment is 108 among the 616 trials that report a genuine target (sentinel values excluded). 287 of those (46.6%) plan for fewer than 100 participants.

  4. Cancer research is mostly interventional.

    462 interventional and 159 observational studies make up this index (74.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1116Phase 248Phase 327Phase 44

Open and recent trials

621 total, page 5 of 13

RECRUITING NA 70 participants

Support for Bereaved Cancer Caregivers

Michigan State University

NCT06662409

RECRUITING NA 70 participants

Decreasing Chemotherapy Induced Distress Using Immersive Virtual Reality in Patients With Cancer

Case Comprehensive Cancer Center

NCT06446115

RECRUITING NA 70 participants

Massage Impact on Sleep in Pediatric Oncology

Children's Hospital of Philadelphia

NCT06892158

RECRUITING NA 70 participants

A Study of Herbal Supplements in Cancer Survivors With Constipation

Memorial Sloan Kettering Cancer Center

NCT07091084

RECRUITING Phase 1 67 participants

Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM

Northwell Health

NCT03213002

RECRUITING Phase 1 65 participants

A Dose Finding Phase 1 of Sarilumab Plus Capecitabine in HER2/Neu-Negative Metastatic Breast Cancer and a Single-arm, Historically-controlled Phase 2 Study of Sarilumab Plus Capecitabine in Stage I-III Triple Negative Breast Cancer With High-Risk Residual Disease (EMPOWER)

University of Southern California

NCT04333706

RECRUITING NA 64 participants

Study of a Support Program for Quality of Life in Chinese Cancer Patients and Survivors

Memorial Sloan Kettering Cancer Center

NCT07454330

RECRUITING NA 64 participants

Intervening on Women's Health for Rural Young Cancer Survivors

University of California, San Diego

NCT06664034

RECRUITING NA 60 participants

Dietary Interventions in Cancer Patients Treated With Immune Checkpoint Inhibitors

University of Pittsburgh

NCT06475807

RECRUITING Phase 2 60 participants

Acupuncture for People Experiencing Period Loss Due to Chemotherapy

Memorial Sloan Kettering Cancer Center

NCT06915116

RECRUITING Phase 2 60 participants

UCSD Image-Guided Cognitive-Sparing Radiosurgery for Brain Metastases

Jona Hattangadi-Gluth

NCT04343157

RECRUITING NA 60 participants

Rehabilitation Outcomes Study

UNC Lineberger Comprehensive Cancer Center

NCT06674889

RECRUITING NA 60 participants

Dyadic Life Review Intervention for Older Patients With Advanced Cancer) and Their Caregivers

University of Rochester

NCT06505122

RECRUITING NA 60 participants

Cultural Tailoring and Pilot Testing of an Inpatient Yoga Therapy Program for Cancer Patients Undergoing Hematopoietic Stem Cell Transplantation in India, Tanzania, and the United States

M.D. Anderson Cancer Center

NCT05681026

RECRUITING Phase 3 60 participants

A Randomized Controlled Trial of Inhaled Tranexamic Acid for the Treatment of Pulmonary Hemorrhage in Cancer Patients

M.D. Anderson Cancer Center

NCT05053867

RECRUITING NA 60 participants

Text -Based Depression Screening Among Cancer Survivors

Medical University of South Carolina

NCT06894849

RECRUITING NA 60 participants

Feasibility of a Technology-Based Intervention for Depression Referral Uptake in Cancer Survivors

Medical University of South Carolina

NCT07091968

RECRUITING NA 60 participants

Artificial Intelligence-Powered Support For Quality Of Life Improvement In Participants With Cancer

Case Comprehensive Cancer Center

NCT07167056

RECRUITING 60 participants

A Digital Art Activity to Enhance Self-Disclosure and the Detection of Psycho-social Distress in Adult Cancer Patients

M.D. Anderson Cancer Center

NCT06127121

RECRUITING Phase 2 56 participants

Two Doses of Psilocybin for the Treatment of MDD in Adults With Cancer

Sunstone Medical

NCT05947383

RECRUITING Phase 2 55 participants

Preoperative Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck

Alain Algazi

NCT03708224

RECRUITING NA 50 participants

Legal Evaluation for Greater Access to Cancer Care (LEGAL-CARE)

University of Alabama at Birmingham

NCT07197515

RECRUITING NA 50 participants

Group Advanced Care Planning Pilot for Veterans

VA Palo Alto Health Care System

NCT06646614

RECRUITING Phase 2 50 participants

Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma

UNC Lineberger Comprehensive Cancer Center

NCT05145400

RECRUITING 50 participants

Assessing Claims of Cannabis as an Anti-cancer Agent (CATA)

HealthPartners Institute

NCT07107607

RECRUITING NA 50 participants

High-Resolution PET-CT Imaging for Surgical Margin Visualization

Vanderbilt-Ingram Cancer Center

NCT06915454

RECRUITING 50 participants

Impact of the Coronavirus (COVID-19) on Patients With Cancer

Stanford University

NCT04330521

RECRUITING NA 50 participants

Yoga to Improve Disparities in Cancer Survivorship

University of California, San Francisco

NCT07165600

RECRUITING 50 participants

Patient Derived Preclinical Models

Mayo Clinic

NCT05324553

RECRUITING NA 50 participants

ProSalud in Latinos Living in Rural/Agricultural Communities Within Moffitt's Catchment Area

H. Lee Moffitt Cancer Center and Research Institute

NCT07218848

RECRUITING NA 50 participants

Feasibility and Acceptability of the Remote Oncology Symptom Assessment Application

University of Pittsburgh

NCT07218874

RECRUITING Phase 1 50 participants

A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of TT125-802 in Subjects With Advanced Solid Tumors

TOLREMO therapeutics

NCT06403436

RECRUITING NA 48 participants

Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

NCT06731998

RECRUITING Phase 1 46 participants

Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases

Baptist Health South Florida

NCT05789589

RECRUITING NA 45 participants

Life at 100.4: An Immersive Social Virtual Reality (VR) Education Tool for Adolescent and Young Adult Cancer Patients and Caregivers

Yale University

NCT07224204

RECRUITING NA 45 participants

Optimizing Care for Cancer Survivors With Depression: Project 3

Medical University of South Carolina

NCT06930729

RECRUITING NA 40 participants

Pilot Study of Mindset Moments Among Adolescent and Young Adult Cancer Survivors

Duke University

NCT06732375

RECRUITING NA 40 participants

Care Coordination Educational Intervention Study for Patients from Rural Areas with Early Stage Cancer

University of Vermont Medical Center

NCT05723250

RECRUITING NA 40 participants

GOLD: Brief Intervention to Reduce Anxiety and Promote Resilience in Families of Youth With Cancer

Stanford University

NCT05415007

RECRUITING NA 40 participants

Adaptation of a Values Assessment Tool

UNC Lineberger Comprehensive Cancer Center

NCT07068477

RECRUITING NA 40 participants

Cognitive Behavioral Theory-assisted Virtual Reality for Chronic CANcer Pain (VR-CAN)

Medstar Health Research Institute

NCT07318519

RECRUITING NA 40 participants

A Novel Intervention for Patients With Cancer

Dana-Farber Cancer Institute

NCT05643027

RECRUITING NA 40 participants

Pilot Study of Management of Facial Paralysis in the Oncologic Patient: Nerve Transfer Techniques to Improve Facial Function and Quality of Life

M.D. Anderson Cancer Center

NCT06667427

RECRUITING Phase 2 38 participants

Study of the CDK4/6 Inhibitor Abemaciclib in Solid Tumors Harboring Genetic Alterations in Genes Encoding D-Type Cyclins or Amplification of CDK4 or CDK6

Dana-Farber Cancer Institute

NCT03310879

RECRUITING NA 38 participants

COBRA: Cancer, Older Adults, Balance and Resistance Activities

Memorial Sloan Kettering Cancer Center

NCT07011862

RECRUITING Phase 2 37 participants

Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors

University of Cincinnati

NCT06416007

RECRUITING NA 35 participants

Mobile Health Intervention to Improve Adherence to Oral Anticancer Therapy

University of California, Irvine

NCT07073807

RECRUITING NA 35 participants

CTNow: A Clinical Trials Education Program for Rural Cancer Patients and Oncology Providers

University of Hawaii

NCT06237816

RECRUITING NA 30 participants

A Study of Shengbai Oral Formula to Assess Safety and Alleviation of Adverse Effects in Cancer Patients Undergoing Chemotherapy

Sutter Health

NCT06706752

RECRUITING NA 30 participants

Intervention to Improve Utilization of Extended Venous Thromboembolism Prophylaxis After Cancer Surgery

Medical University of South Carolina

NCT06451003

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Phase Distribution

PhaseTrial count
Phase 1 116
Phase 2 48
Phase 3 27
Phase 4 4

Named interventions

Most-linked intervention names on Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Usual Care Other
6 trials
Carboplatin Drug
6 trials
Bevacizumab Drug
6 trials
Pembrolizumab Drug
6 trials
Radiation therapy Radiation
4 trials
Usual Care Behavioral
4 trials
Atezolizumab Drug
4 trials
Placebo Drug
4 trials

US sites by state

Facility locations filed on Cancer trials. A trial with sites in several states counts in each.

California 142 trials
Texas 106 trials
Florida 90 trials
New York 88 trials
Pennsylvania 68 trials
North Carolina 63 trials
Massachusetts 59 trials
Tennessee 50 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Cancer page

621 registered trials, 279 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cancer condition card totals 621 registered trials; most-linked intervention Usual Care; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.