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RECRUITING Phase 2

UCSD Image-Guided Cognitive-Sparing Radiosurgery for Brain Metastases

NCT04343157 · View on ClinicalTrials.gov ↗

Study Summary

In this proposal, the investigators introduce advanced diffusion and volumetric imaging techniques along with innovative, automated image parcellation methods to identify critical brain regions, incorporate into cognitive-sparing SRS, and analyze biomarkers of radiation response. This work will advance the investigators' understanding of neurocognitive changes after brain SRS and help create interventions that preserve cognitive-function in brain metastases patients.

Interventions

  • RADIATION Cognitive Sparing Brain Stereotactic Radiosurgery (SRS)

Study Locations (1)

California

  • Moores Cancer Center — San Diego

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2019-05-01
Est. Completion 2024-12-31
Phase Phase 2

Sponsor

Jona Hattangadi-Gluth

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04343157

The ClinicalTrials.gov registry entry for NCT04343157 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Jona Hattangadi-Gluth, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Cancer appearing as the primary indexed condition, and to 1 intervention — of which Cognitive Sparing Brain Stereotactic Radiosurgery (SRS) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04343157 reports 1 study location spanning 1 distinct geographic area — top geographies include California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04343157 about?

NCT04343157 is a clinical study titled "UCSD Image-Guided Cognitive-Sparing Radiosurgery for Brain Metastases". In this proposal, the investigators introduce advanced diffusion and volumetric imaging techniques along with innovative, automated image parcellation methods to identify critical brain regions, incorporate into cognitive-sparing SRS, and analyze biomarkers of radiation response. This work will adva...

What is the current status of trial NCT04343157?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2019-05-01. Estimated completion is 2024-12-31.

What conditions does trial NCT04343157 study?

This clinical trial studies the following conditions: Cancer, Brain Metastases, Adult, Neurocognitive Function. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04343157?

The interventions under investigation include: Cognitive Sparing Brain Stereotactic Radiosurgery (SRS) (RADIATION). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04343157?

This trial is sponsored by Jona Hattangadi-Gluth, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04343157 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial