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NCT03708224 · ClinicalTrials.gov registry record · Phase 2

Preoperative Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck

A Phase 2 study of Cancer and Head and Neck Cancer, sponsored by Alain Algazi.

Recruiting
Registry status
Phase 2
Development phase
55
Enrollment target
1
Study location

NCT03708224 is a Phase 2 study of Cancer and Head and Neck Cancer that is actively recruiting participants, run by Alain Algazi. The registered enrollment target is 55 participants, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03708224, a Phase 2 study of Cancer and Head and Neck Cancer, is actively recruiting participants, sponsored by Alain Algazi.

RECRUITING
Registry status
Phase 2
Development phase
55 participants
Enrollment target
1
Study location

Study Summary

To determine the effect of neoadjuvant atezolizumab alone or in combination with other immune modulating agents on T-cell infiltration in advanced SCCHN. To determine the impact of neo-adjuvant immunotherapy on surgical outcomes.

Conditions Studied

Cancer Head and Neck Cancer Squamous Cell Carcinoma Carcinoma

Interventions

  • BIOLOGICAL Atezolizumab
  • BIOLOGICAL Tocilizumab
  • BIOLOGICAL Tiragolumab

Study Locations (1)

California

  • University of San Francisco, California - San Francisco

Trial Details

FieldValue
Enrollment Target 55 participants
Start Date 2019-03-08
Est. Completion 2028-06-30
Phase Phase 2

Sponsor

Alain Algazi

1 total trials

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What the Registry Record Tells You About NCT03708224

The ClinicalTrials.gov registry entry for NCT03708224 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 55 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (98% lower). The listed sponsor is Alain Algazi, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Cancer appearing as the primary indexed condition, and to 3 interventions - of which Atezolizumab is the first listed.

NCT03708224 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT03708224 about?

NCT03708224 is a clinical study titled "Preoperative Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck". To determine the effect of neoadjuvant atezolizumab alone or in combination with other immune modulating agents on T-cell infiltration in advanced SCCHN. To determine the impact of neo-adjuvant immunotherapy on surgical outcomes.

What is the current status of trial NCT03708224?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 55 participants. The study started on 2019-03-08. Estimated completion is 2028-06-30.

What conditions does trial NCT03708224 study?

This clinical trial studies the following conditions: Cancer, Head and Neck Cancer, Squamous Cell Carcinoma, Carcinoma.

What interventions are being tested in trial NCT03708224?

The interventions under investigation include: Atezolizumab (BIOLOGICAL), Tocilizumab (BIOLOGICAL), Tiragolumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT03708224?

This trial is sponsored by Alain Algazi, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03708224 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.