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NCT05324553 · ClinicalTrials.gov registry record
Patient Derived Preclinical Models
A clinical trial of Cancer, sponsored by Mayo Clinic.
- Recruiting
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT05324553: Recruiting study of Cancer, sponsored by Mayo Clinic.
NCT05324553 is a study of Cancer that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 50 participants, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05324553, a study of Cancer, is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Study goal is to collect tumor specimens that may inform cancer biology to eventually improve outcomes for patients with cancer. This proposal represents a highly collaborative effort to support cancer research with the goal of developing novel therapeutic strategies using patient derived preclinical models. This study is being done to collect samples of tumor tissues, matched normal tissue when possible, and approximately 50 mL of blood.
Primary Outcome
Sequencing data from DNA and RNA will be integrated into a visualization platform to allow individualized study of patient tumor mutations, rearrangements, and RNA expression. Genomically informed analysis will be employed to select potential targets for drug screening in the patient-derived 3D models and determine how many specimens are able to grow as 3D models. In some cases, immunostain results may be analyzed for correlation to RNA expression levels.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Blood Collection
- PROCEDURE Tissue Collection
- DIAGNOSTIC_TEST Buccal Swab
Study Locations (1)
Minnesota
- Mayo Clinic in Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2022-04-06 |
| Est. Completion | 2028-03-31 |
What NCT05324553 shows while recruiting
NCT05324553 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Cancer appearing as the primary indexed condition, and to 3 interventions - of which Blood Collection is the first listed.
NCT05324553 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT05324553 about?
NCT05324553 is a clinical study titled "Patient Derived Preclinical Models". Study goal is to collect tumor specimens that may inform cancer biology to eventually improve outcomes for patients with cancer. This proposal represents a highly collaborative effort to support cancer research with the goal of developing novel therapeutic strategies using patient derived preclinica...
What is the current status of trial NCT05324553?
This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2022-04-06. Estimated completion is 2028-03-31.
What conditions does trial NCT05324553 study?
This clinical trial studies the following conditions: Cancer.
What interventions are being tested in trial NCT05324553?
The interventions under investigation include: Blood Collection (DIAGNOSTIC_TEST), Tissue Collection (PROCEDURE), Buccal Swab (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT05324553?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05324553 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05324553's enrollment target sits among peer trials
50 422nd of 615 higher than 179 of 615 other Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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