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ClinicalTrials.gov 279 recruiting now early-phase tilt #6 of 28,963 conditions

Cancer: early-phase trial registry

279 of 621 indexed Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #6 of 28,963 conditions by registered trial count.

621 US clinical trials · 279 currently recruiting · #6 of 28,963 conditions by registered trial count

Cancer: 621 US clinical trials tracked, 279 recruiting.

Cancer is the subject of 621 registered US clinical trials on ClinicalTrials.gov, 279 of them currently open to new participants. 31 are in Phase 3-4 (later-stage) and 164 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 31 of these trials.

Open enrollment, early-phase tilt

Cancer has 621 registered US clinical trials, 279 of them open to new participants right now, about 45% of the total.

279
recruiting participants now
45%
of trials open to enrollment
31
in Phase 3-4 (later-stage)
31
top sponsor: M.D. Anderson Cancer Center

Corpus placement: #6 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Cancer is recruiting above its size-band peers.

    279 of 621 indexed trials (44.9%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Cancer trials is spread across many organizations.

    M.D. Anderson Cancer Center accounts for 31 of 621 trials (5%). 270 distinct sponsors appear on at least one study for this condition label.

  3. Typical Cancer enrolment sits around 108 participants.

    Median target enrolment is 108 among the 616 trials that report a genuine target (sentinel values excluded). 287 of those (46.6%) plan for fewer than 100 participants.

  4. Cancer research is mostly interventional.

    462 interventional and 159 observational studies make up this index (74.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1116Phase 248Phase 327Phase 44

Open and recent trials

621 total, page 4 of 13

RECRUITING 150 participants

Development of Brief Positive Affect Treatment (PAT) for Caregivers of Patients With Advanced Cancer

M.D. Anderson Cancer Center

NCT05904782

RECRUITING NA 150 participants

Radiotherapy Patient Education With Virtual Reality

University of Miami

NCT06506435

RECRUITING NA 150 participants

Remote Temperature Monitoring of Patients At Risk for Developing Fever

AION Biosystems

NCT06752512

RECRUITING Phase 2 140 participants

A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors

EpicentRx

NCT04673942

RECRUITING Phase 1 132 participants

A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

Conjupro Biotherapeutics

NCT05948865

RECRUITING 130 participants

Long-Term Follow-Up of Recipient of Gene Transfer Research

M.D. Anderson Cancer Center

NCT01492036

RECRUITING Phase 1 130 participants

Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors

MBrace Therapeutics

NCT06014658

RECRUITING NA 126 participants

Heuristic Tool To Improve Symptom Self-Management in Adolescents and Young Adults With Cancer

Virginia Commonwealth University

NCT05958316

RECRUITING 125 participants

Fatigue and Molecular Mechanisms in Cancer Patients Receiving CCRT

University of California, San Francisco

NCT06633224

RECRUITING 120 participants

A Study of Live Tumor Fragments of Surgical Resections

Mayo Clinic

NCT07000864

RECRUITING 120 participants

eMOTION: Examining Implicit Attitudes in Physical Activity Engagement

University of Southern California

NCT07044570

RECRUITING NA 120 participants

Healthy Living Anson Study

University of North Carolina, Chapel Hill

NCT07126587

RECRUITING NA 120 participants

Evaluating Microarray Pharmacogenetic Testing in Cancer Patients

Wake Forest University Health Sciences

NCT06489041

RECRUITING NA 120 participants

Addressing Social Determinants of Health Among Metro Detroit Cancer Survivors

Barbara Ann Karmanos Cancer Institute

NCT06908629

RECRUITING NA 114 participants

Breast Re-irradiation After Second Ipsilateral Lumpectomy

Youssef Zeidan

NCT06867484

RECRUITING Phase 1 110 participants

A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors

Alterome Therapeutics

NCT06533059

RECRUITING NA 110 participants

Assessment of Multi-Level Interventions to Improve Adherence to Oral Medications in Cancer Patients

Thomas Jefferson University

NCT03245411

RECRUITING NA 108 participants

Chinese American Cancer Survivors Writing Study

New York University

NCT05456100

RECRUITING 100 participants

Tumor Related Epilepsy

National Institute of Neurological Disorders and Stroke (NINDS)

NCT02639325

RECRUITING NA 100 participants

Leading Healthy Eating and Activity Promotion Program

University of Alabama at Birmingham

NCT06868524

RECRUITING NA 100 participants

Enhancing Motivation to Quit Smoking Via Self-Help Intervention Targeted to Cancer Type

University of Utah

NCT06484179

RECRUITING NA 100 participants

The PRISM-Social Needs (PRISM-SN) Intervention for Adolescents and Young Adults With Cancer

Seattle Children's Hospital

NCT06242964

RECRUITING 100 participants

EXErcise Regimen Designed to Improve Functional Mobility, Body Composition, and Strength After Treatment for Cancer

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

NCT06083324

RECRUITING NA 100 participants

A Biobehavioral Intervention for Latino/Hispanic Young Adults with Cancer

University of California, Irvine

NCT06338475

RECRUITING NA 100 participants

Nourishing Hope: The Impact of Nutrition in Cancer Treatment and Recovery in Maine

Yale University

NCT07076004

RECRUITING NA 100 participants

The Florida ASCENT Study

University of Florida

NCT07042243

RECRUITING NA 100 participants

F.L.O.S.S. Project (Facilitated Lessons on Oral and Systemic Health in Survivors)

Georgetown University

NCT06315855

RECRUITING 100 participants

Young Adult Infusion Space Experience Satisfaction Survey

UNC Lineberger Comprehensive Cancer Center

NCT05720546

RECRUITING NA 98 participants

Pleuroscopy First Versus Thoracentesis First in Patients With Suspected Malignant Pleural Effusions

Icahn School of Medicine at Mount Sinai

NCT06892691

RECRUITING Phase 1 96 participants

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

National Cancer Institute (NCI)

NCT05588141

RECRUITING Phase 2 93 participants

Evaluating Genomic Testing in Human Cancer & Outcomes of Targeted Therapies

Rachel Miller

NCT03089554

RECRUITING Phase 1 90 participants

Study to Investigate the Efficacy and Safety of RP1 in Adult Patients With Organ Transplants and Advanced Skin Malignancies

Replimune

NCT04349436

RECRUITING Phase 1 90 participants

A Study of NTX-1088, a Monoclonal Antibody Targeting the Poliovirus Receptor (PVR, CD155), as Monotherapy and Combined With Pembrolizumab

Nectin Therapeutics

NCT05378425

RECRUITING NA 90 participants

Supportive Care Intervention for Outpatient Stem Cell Transplant Patients

Victor Wang

NCT06564233

RECRUITING NA 86 participants

Visual Communication: Digital Tool to Improve the Understanding of Treatment Options for Patients With Cancer and Increase Satisfaction of the Overall Experience for Patients, Caregivers, and Providers

NYU Langone Health

NCT06927050

RECRUITING NA 85 participants

Revealing Information Genuinely & Honestly Across Time - Communication Preferences Visit

St. Jude Children's Research Hospital

NCT06993688

RECRUITING NA 84 participants

A Youth-led Intervention to Reduce Healthcare Disparities in Cancer Screening

Rutgers, The State University of New Jersey

NCT07008781

RECRUITING NA 84 participants

Testing a Brief Motivational Intervention to Increase Physical Activity for Cancer Survivors

Stony Brook University

NCT07215091

RECRUITING Phase 1 80 participants

Impact of Daily Oral Cannabis Doses in Patients With Cancer

Shanna Babalonis, PhD

NCT06601218

RECRUITING 80 participants

Validation of the Screen of Cancer Survivorship - Occupational Therapy Services (SOCS-OTS) Tool for Use in a Physical Medicine Rehabilitation Clinic

M.D. Anderson Cancer Center

NCT06329531

RECRUITING 80 participants

Patient Descriptors Of Cancer-Related Fatigue: A Mixed Methods Pilot Study Of Cancer Survivors

Wake Forest University Health Sciences

NCT06634381

RECRUITING NA 80 participants

Examining the Feasibility and Impact of a Clinic-based Food Farmacy and Digital Culinary Medicine Program Among Cancer Survivors Treated in a Safety Net Hospital

M.D. Anderson Cancer Center

NCT06760754

RECRUITING NA 80 participants

Resilience Mobile App for Teens and Young Adults With Cancer

Seattle Children's Hospital

NCT05842902

RECRUITING Phase 1 80 participants

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

Angiex

NCT06440005

RECRUITING NA 80 participants

Cancer and Mild Cognitive Impairment Dyadic Intervention

Duke University

NCT05144516

RECRUITING Phase 1 78 participants

An Open-Label Study of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors

Shenzhen Ionova Life Sciences Co.

NCT04443088

RECRUITING Phase 1 75 participants

Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer

Heike E Daldrup-Link

NCT01542879

RECRUITING NA 75 participants

Cancer-related Fatigue and Its Biological Contributors in Adolescent and Young Adult Brain Tumor Survivors: Effects of a Tele-exercise Intervention

M.D. Anderson Cancer Center

NCT07186556

RECRUITING NA 75 participants

Comprehensive Tobacco Cessation for Cancer Patients and Survivors

Virginia Commonwealth University

NCT05805722

RECRUITING NA 74 participants

BfedBwell Optimization Pilot

University of Colorado, Denver

NCT06184256

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Phase Distribution

PhaseTrial count
Phase 1 116
Phase 2 48
Phase 3 27
Phase 4 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Cancer right now

279 recruiting of 621 indexed (45% open).

Phase mix: 31 late (III/IV) vs 164 early (I/II) (early-phase heavy).

Top sponsor: M.D. Anderson Cancer Center (31 trials), 9 others listed. 50 shown below, recruiting first. #6 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Cancer?

PlainTrial tracks 621 US clinical trials for Cancer, of which 279 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.