Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Cancer: early-phase trial registry
279 of 621 indexed Cancer trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #6 of 28,707 conditions by registered trial count.
621 US clinical trials · 279 currently recruiting · #6 of 28,707 conditions by registered trial count
Cancer: 621 US clinical trials tracked, 279 recruiting.
Cancer is the subject of 621 registered US clinical trials on ClinicalTrials.gov, 279 of them currently open to new participants. 31 are in Phase 3-4 (later-stage) and 164 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 31 of these trials.
Enrollment posture brief
Registry condition cancer
OPEN 279 | RECR 45% | LATE 31 | EARLY 164 | RANK #6 | SPON 31
Volume-matched condition peers
Nearest open-share peer: Duchenne Muscular Dystrophy (45% recruiting · 49 trials)
Cancer lists 279 open slots (45% of 621 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Cancer is recruiting above its size-band peers.
279 of 621 indexed trials (44.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Cancer trials is spread across many organizations.
M.D. Anderson Cancer Center accounts for 31 of 621 trials (5%). 270 distinct sponsors appear on at least one study for this condition label.
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Typical Cancer enrolment sits around 108 participants.
Median target enrolment is 108 among the 616 trials that report a genuine target (sentinel values excluded). 287 of those (46.6%) plan for fewer than 100 participants.
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Cancer research is mostly interventional.
462 interventional and 159 observational studies make up this index (74.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
621 total, page 3 of 13
ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors
Immatics US
NCT03686124
Implementation of eHealth Delivery Alternatives for Cancer Genetic Testing for Hereditary Cancer (eREACH3)
Abramson Cancer Center at Penn Medicine
NCT07471958
A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials
University of Florida
NCT05655494
INTERogating Cancer for Etiology, Prevention and Therapy Navigation
Mayo Clinic
NCT06008392
The STOP-MED CTRCD Trial
University Health Network, Toronto
NCT06183437
A Study in Patients With Advanced Cancers
BiOneCure Therapeutics
NCT05320588
A Single Arm Pilot Trial of a Social Network Intervention
University of Rochester
NCT05745038
Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067
Simcha IL-18
NCT04787042
Comprehensive Connected Cancer Care (C4): Intervention Evaluation
Timothy Mullett
NCT06326567
Registry Study for Proton Therapy Clinical Outcomes and Long-Term Follow-up
Center for Biomedical Research
NCT02070328
Cryopreservation of Ovarian Tissue
Weill Medical College of Cornell University
NCT01558544
Enhancing Triadic Communication About Cognition for Older Adults With Alzheimer's Disease or Related Dementias Facing a Cancer Management Decision
University of Rochester
NCT06313853
Survivors Uniting for Remote Guided Exercise
Colorado State University
NCT07290309
ConnectedNest: a Digital Platform Connecting Individuals With Cancer to Social Care
University of Minnesota
NCT06559228
eMOTION: Examining Affective Mechanisms in Physical Activity Engagement
University of Southern California
NCT06570642
IMPACT (IMproving Proactive Approaches for Cancer Survivors' Mental Health Treatment)
Medical University of South Carolina
NCT06582784
Wellness App for Sleep Disturbance in Hematological Cancer Patients
The University of Texas Health Science Center at San Antonio
NCT05294991
A Phase 1 Study of JMT108 in Participants With Advanced Solid Tumors
Conjupro Biotherapeutics
NCT07317505
DISCO: A Patient Intervention to Reduce the Financial Burden of Cancer
Lauren Hamel
NCT04766190
Making Healthy Habits Stick
University of Tennessee
NCT06745180
Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors
Duke University
NCT06371768
Correlates of CRCI and Gut Microbiome Dysbiosis; a Pilot Study
The University of Texas Medical Branch, Galveston
NCT06098404
Survivorship Plan HEalth REcord (SPHERE) Implementation Trial
Indiana University
NCT05346796
A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors
Krystal Biotech
NCT05970497
Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors
UNC Lineberger Comprehensive Cancer Center
NCT06848491
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
A2 Biotherapeutics
NCT06682793
TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
Tizona Therapeutics
NCT04485013
The Care Tracker Study: Using Patient-Reported Data to Address Racial Disparity in Cancer Treatment
UNC Lineberger Comprehensive Cancer Center
NCT06096623
Testing Gene PilotLX With Latinx Cancer Patients
Fox Chase Cancer Center
NCT06476938
Improving Cancer-related Fatigue, Sexual Dysfunction and Quality of Life in Older Men With Cancer and Androgen Deficiency
Seattle Institute for Biomedical and Clinical Research
NCT04301765
Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies
Circle Pharma
NCT06577987
xDRIVE for Florida-based Cancer Patients
First Ascent Biomedical
NCT07167381
Optimizing the AYA Survivors' Coping and Emotional Needs Toolkit
East Carolina University
NCT07173205
Ultralow Dose PET Imaging of 18F-FDG Uptake
Akiva Mintz
NCT06956391
Testicular Tissue Cryopreservation in Children
Mayo Clinic
NCT02872532
The Impact of CAR-T Cell Therapy on Fertility; A Patient Survey
Blood Cancer United
NCT07173322
Online Tai Chi Intervention to Promote Smoking Cessation Among Cancer Survivors
Ohio State University Comprehensive Cancer Center
NCT05941858
ChangeGradients: Promoting Adolescent Health Behavior Change
University of California, San Francisco
NCT04110756
Transdiagnostic Intervention to Reduce Internalized Health-Related Stigma
University of Florida
NCT05561595
CAncer TReatment INformed by the Molecular Tumor Board At Dartmouth
Dartmouth-Hitchcock Medical Center
NCT05405413
Health Benefits of Writing Therapy Among Asian American Cancer Survivors
M.D. Anderson Cancer Center
NCT06367959
A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
Alterome Therapeutics
NCT06835569
Preserving Physical Function in Older Adults With Cancer: Impact of an Optimizing Nutrition Intervention Applied Before and After Surgery
VA Office of Research and Development
NCT05912257
Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer
M.D. Anderson Cancer Center
NCT05474846
Novel Outreach Methods to Increase Enrollment to Early Phase Clinical Trials
University of Chicago
NCT05886764
A Randomized Trial of a Mobile Health Exercise Intervention for Older Adults With Myeloid Neoplasms
University of Rochester
NCT04981821
A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents
OncoResponse
NCT06090266
Positron Emission Tomography (PET) Imaging of Thrombosis
Massachusetts General Hospital
NCT03830320
Active Living After Cancer: Implementation Within Be Well Acres Homes
M.D. Anderson Cancer Center
NCT06907706
Expanding the Support of Family Caregivers of Diverse Patients With Cancer and Diabetes
UNC Lineberger Comprehensive Cancer Center
NCT07061652
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 116 |
| Phase 2 | 48 |
| Phase 3 | 27 |
| Phase 4 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Cancer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Cancer page
621 registered trials, 279 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 279 Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- M.D. Anderson Cancer Center sponsors the most Cancer trials on record, review their full trial history before evaluating a specific study. See M.D. Anderson Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cancer condition card totals 621 registered trials; most-linked intervention Usual Care; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.