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ClinicalTrials.gov 279 recruiting now early-phase tilt #6 of 28,963 conditions

Cancer: early-phase trial registry

279 of 621 indexed Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #6 of 28,963 conditions by registered trial count.

621 US clinical trials · 279 currently recruiting · #6 of 28,963 conditions by registered trial count

Cancer: 621 US clinical trials tracked, 279 recruiting.

Cancer is the subject of 621 registered US clinical trials on ClinicalTrials.gov, 279 of them currently open to new participants. 31 are in Phase 3-4 (later-stage) and 164 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 31 of these trials.

Open enrollment, early-phase tilt

Cancer has 621 registered US clinical trials, 279 of them open to new participants right now, about 45% of the total.

279
recruiting participants now
45%
of trials open to enrollment
31
in Phase 3-4 (later-stage)
31
top sponsor: M.D. Anderson Cancer Center

Corpus placement: #6 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Cancer is recruiting above its size-band peers.

    279 of 621 indexed trials (44.9%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Cancer trials is spread across many organizations.

    M.D. Anderson Cancer Center accounts for 31 of 621 trials (5%). 270 distinct sponsors appear on at least one study for this condition label.

  3. Typical Cancer enrolment sits around 108 participants.

    Median target enrolment is 108 among the 616 trials that report a genuine target (sentinel values excluded). 287 of those (46.6%) plan for fewer than 100 participants.

  4. Cancer research is mostly interventional.

    462 interventional and 159 observational studies make up this index (74.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1116Phase 248Phase 327Phase 44

Open and recent trials

621 total, page 3 of 13

RECRUITING Phase 1 375 participants

ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

Immatics US

NCT03686124

RECRUITING 360 participants

Implementation of eHealth Delivery Alternatives for Cancer Genetic Testing for Hereditary Cancer (eREACH3)

Abramson Cancer Center at Penn Medicine

NCT07471958

RECRUITING 350 participants

A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials

University of Florida

NCT05655494

RECRUITING 350 participants

INTERogating Cancer for Etiology, Prevention and Therapy Navigation

Mayo Clinic

NCT06008392

RECRUITING Phase 4 335 participants

The STOP-MED CTRCD Trial

University Health Network, Toronto

NCT06183437

RECRUITING Phase 1 332 participants

A Study in Patients With Advanced Cancers

BiOneCure Therapeutics

NCT05320588

RECRUITING NA 330 participants

A Single Arm Pilot Trial of a Social Network Intervention

University of Rochester

NCT05745038

RECRUITING Phase 1 316 participants

Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067

Simcha IL-18

NCT04787042

RECRUITING NA 300 participants

Comprehensive Connected Cancer Care (C4): Intervention Evaluation

Timothy Mullett

NCT06326567

RECRUITING 300 participants

Registry Study for Proton Therapy Clinical Outcomes and Long-Term Follow-up

Center for Biomedical Research

NCT02070328

RECRUITING NA 300 participants

Cryopreservation of Ovarian Tissue

Weill Medical College of Cornell University

NCT01558544

RECRUITING NA 300 participants

Enhancing Triadic Communication About Cognition for Older Adults With Alzheimer's Disease or Related Dementias Facing a Cancer Management Decision

University of Rochester

NCT06313853

RECRUITING NA 300 participants

Survivors Uniting for Remote Guided Exercise

Colorado State University

NCT07290309

RECRUITING Phase 2 300 participants

ConnectedNest: a Digital Platform Connecting Individuals With Cancer to Social Care

University of Minnesota

NCT06559228

RECRUITING NA 280 participants

eMOTION: Examining Affective Mechanisms in Physical Activity Engagement

University of Southern California

NCT06570642

RECRUITING NA 279 participants

IMPACT (IMproving Proactive Approaches for Cancer Survivors' Mental Health Treatment)

Medical University of South Carolina

NCT06582784

RECRUITING NA 276 participants

Wellness App for Sleep Disturbance in Hematological Cancer Patients

The University of Texas Health Science Center at San Antonio

NCT05294991

RECRUITING Phase 1 270 participants

A Phase 1 Study of JMT108 in Participants With Advanced Solid Tumors

Conjupro Biotherapeutics

NCT07317505

RECRUITING NA 260 participants

DISCO: A Patient Intervention to Reduce the Financial Burden of Cancer

Lauren Hamel

NCT04766190

RECRUITING NA 260 participants

Making Healthy Habits Stick

University of Tennessee

NCT06745180

RECRUITING NA 260 participants

Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors

Duke University

NCT06371768

RECRUITING 250 participants

Correlates of CRCI and Gut Microbiome Dysbiosis; a Pilot Study

The University of Texas Medical Branch, Galveston

NCT06098404

RECRUITING NA 250 participants

Survivorship Plan HEalth REcord (SPHERE) Implementation Trial

Indiana University

NCT05346796

RECRUITING Phase 1 240 participants

A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

Krystal Biotech

NCT05970497

RECRUITING NA 240 participants

Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors

UNC Lineberger Comprehensive Cancer Center

NCT06848491

RECRUITING Phase 1 240 participants

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

A2 Biotherapeutics

NCT06682793

RECRUITING Phase 1 240 participants

TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers

Tizona Therapeutics

NCT04485013

RECRUITING NA 240 participants

The Care Tracker Study: Using Patient-Reported Data to Address Racial Disparity in Cancer Treatment

UNC Lineberger Comprehensive Cancer Center

NCT06096623

RECRUITING NA 232 participants

Testing Gene PilotLX With Latinx Cancer Patients

Fox Chase Cancer Center

NCT06476938

RECRUITING Phase 2 230 participants

Improving Cancer-related Fatigue, Sexual Dysfunction and Quality of Life in Older Men With Cancer and Androgen Deficiency

Seattle Institute for Biomedical and Clinical Research

NCT04301765

RECRUITING Phase 1 220 participants

Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies

Circle Pharma

NCT06577987

RECRUITING NA 210 participants

xDRIVE for Florida-based Cancer Patients

First Ascent Biomedical

NCT07167381

RECRUITING NA 208 participants

Optimizing the AYA Survivors' Coping and Emotional Needs Toolkit

East Carolina University

NCT07173205

RECRUITING Phase 2 200 participants

Ultralow Dose PET Imaging of 18F-FDG Uptake

Akiva Mintz

NCT06956391

RECRUITING NA 200 participants

Testicular Tissue Cryopreservation in Children

Mayo Clinic

NCT02872532

RECRUITING 200 participants

The Impact of CAR-T Cell Therapy on Fertility; A Patient Survey

Blood Cancer United

NCT07173322

RECRUITING NA 200 participants

Online Tai Chi Intervention to Promote Smoking Cessation Among Cancer Survivors

Ohio State University Comprehensive Cancer Center

NCT05941858

RECRUITING NA 200 participants

ChangeGradients: Promoting Adolescent Health Behavior Change

University of California, San Francisco

NCT04110756

RECRUITING NA 195 participants

Transdiagnostic Intervention to Reduce Internalized Health-Related Stigma

University of Florida

NCT05561595

RECRUITING Phase 2 192 participants

CAncer TReatment INformed by the Molecular Tumor Board At Dartmouth

Dartmouth-Hitchcock Medical Center

NCT05405413

RECRUITING NA 192 participants

Health Benefits of Writing Therapy Among Asian American Cancer Survivors

M.D. Anderson Cancer Center

NCT06367959

RECRUITING Phase 1 188 participants

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

Alterome Therapeutics

NCT06835569

RECRUITING NA 188 participants

Preserving Physical Function in Older Adults With Cancer: Impact of an Optimizing Nutrition Intervention Applied Before and After Surgery

VA Office of Research and Development

NCT05912257

RECRUITING Phase 2 188 participants

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

M.D. Anderson Cancer Center

NCT05474846

RECRUITING NA 180 participants

Novel Outreach Methods to Increase Enrollment to Early Phase Clinical Trials

University of Chicago

NCT05886764

RECRUITING NA 170 participants

A Randomized Trial of a Mobile Health Exercise Intervention for Older Adults With Myeloid Neoplasms

University of Rochester

NCT04981821

RECRUITING Phase 1 168 participants

A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents

OncoResponse

NCT06090266

RECRUITING Phase 1 165 participants

Positron Emission Tomography (PET) Imaging of Thrombosis

Massachusetts General Hospital

NCT03830320

RECRUITING NA 164 participants

Active Living After Cancer: Implementation Within Be Well Acres Homes

M.D. Anderson Cancer Center

NCT06907706

RECRUITING NA 162 participants

Expanding the Support of Family Caregivers of Diverse Patients With Cancer and Diabetes

UNC Lineberger Comprehensive Cancer Center

NCT07061652

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Phase Distribution

PhaseTrial count
Phase 1 116
Phase 2 48
Phase 3 27
Phase 4 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Cancer right now

279 recruiting of 621 indexed (45% open).

Phase mix: 31 late (III/IV) vs 164 early (I/II) (early-phase heavy).

Top sponsor: M.D. Anderson Cancer Center (31 trials), 9 others listed. 50 shown below, recruiting first. #6 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Cancer?

PlainTrial tracks 621 US clinical trials for Cancer, of which 279 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.