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Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies
NCT06577987 · View on ClinicalTrials.gov ↗
Study Summary
This is a first-in-human, multicenter, open-label, phase 1 study to evaluate safety, tolerability, and efficacy of CID-078, a Cyclin A/B-RxL inhibitor, in patients with advanced solid tumors.
Conditions Studied
Interventions
- DRUG CID-078 Monotherapy
Study Locations (10)
Texas
- MD Anderson Cancer Center — Houston
- NEXT Oncology — San Antonio
Florida
- Florida Cancer Specialists — Sarasota
Massachusetts
- Dana Farber Cancer Institute — Boston
Michigan
- START Midwest — Grand Rapids
Nevada
- Comprehensive Cancer Centers of Nevada — Las Vegas
Ohio
- UH Seidman Cancer Center — Cleveland
Oregon
- Oregon Health and Science University — Portland
Tennessee
- Sarah Cannon Research Institute — Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 220 participants |
| Start Date | 2024-08-14 |
| Est. Completion | 2027-03-14 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06577987
The ClinicalTrials.gov registry entry for NCT06577987 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 220 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Circle Pharma, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 10 conditions, with Cancer appearing as the primary indexed condition, and to 1 intervention — of which CID-078 Monotherapy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06577987 reports 10 study locations spanning 9 distinct geographic areas — top geographies include Texas, Florida, Massachusetts. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06577987 about?
NCT06577987 is a clinical study titled "Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies". This is a first-in-human, multicenter, open-label, phase 1 study to evaluate safety, tolerability, and efficacy of CID-078, a Cyclin A/B-RxL inhibitor, in patients with advanced solid tumors.
What is the current status of trial NCT06577987?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 220 participants. The study started on 2024-08-14. Estimated completion is 2027-03-14.
What conditions does trial NCT06577987 study?
This clinical trial studies the following conditions: Cancer, Lung Cancer, Advanced Solid Tumor, Triple Negative Breast Cancer, Breast Neoplasms. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06577987?
The interventions under investigation include: CID-078 Monotherapy (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06577987?
This trial is sponsored by Circle Pharma, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06577987 being conducted?
This trial has 10 study locations across Florida, Massachusetts, Michigan, Nevada, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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