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ClinicalTrials.gov 279 recruiting now early-phase tilt #6 of 28,963 conditions

Cancer: early-phase trial registry

279 of 621 indexed Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #6 of 28,963 conditions by registered trial count.

621 US clinical trials · 279 currently recruiting · #6 of 28,963 conditions by registered trial count

Cancer: 621 US clinical trials tracked, 279 recruiting.

Cancer is the subject of 621 registered US clinical trials on ClinicalTrials.gov, 279 of them currently open to new participants. 31 are in Phase 3-4 (later-stage) and 164 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 31 of these trials.

Open enrollment, early-phase tilt

Cancer has 621 registered US clinical trials, 279 of them open to new participants right now, about 45% of the total.

279
recruiting participants now
45%
of trials open to enrollment
31
in Phase 3-4 (later-stage)
31
top sponsor: M.D. Anderson Cancer Center

Corpus placement: #6 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Cancer is recruiting above its size-band peers.

    279 of 621 indexed trials (44.9%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Cancer trials is spread across many organizations.

    M.D. Anderson Cancer Center accounts for 31 of 621 trials (5%). 270 distinct sponsors appear on at least one study for this condition label.

  3. Typical Cancer enrolment sits around 108 participants.

    Median target enrolment is 108 among the 616 trials that report a genuine target (sentinel values excluded). 287 of those (46.6%) plan for fewer than 100 participants.

  4. Cancer research is mostly interventional.

    462 interventional and 159 observational studies make up this index (74.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1116Phase 248Phase 327Phase 44

Open and recent trials

621 total, page 2 of 13

RECRUITING 1,025 participants

Quality of Life (QoL) Assessment in Cancer Patients and Survivors With Dermatologic Conditions Using Dermatologic QoL Instruments

Memorial Sloan Kettering Cancer Center

NCT02296450

RECRUITING NA 1,020 participants

A Decisional Intervention for Older Adults With Acute Myeloid Leukemia and Their Caregivers

University of Rochester

NCT06697600

RECRUITING 1,000 participants

Association Between Exercise, Patient-Reported Outcomes, and Clinical Events in Adult Cancer Survivors

Memorial Sloan Kettering Cancer Center

NCT07030686

RECRUITING 1,000 participants

Cannabis Use Registry to Improve Overall Understanding of Symptoms (CURIOUS)

HealthPartners Institute

NCT07227324

RECRUITING 1,000 participants

Precision Cancer Medicine for Advanced Cancer Through High-throughput Sequencing

Ohio State University Comprehensive Cancer Center

NCT02090530

RECRUITING NA 1,000 participants

eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

Abramson Cancer Center at Penn Medicine

NCT05427240

RECRUITING 1,000 participants

Prevent Cancer- Greenville

Prisma Health-Upstate

NCT04947098

RECRUITING Phase 3 996 participants

DOAC - Dosing Options in AntiCoagulation Prophylaxis

University of Vermont

NCT07005024

RECRUITING NA 994 participants

GC-PRO Intervention

University of Minnesota

NCT06671704

RECRUITING Phase 3 880 participants

Post-Discharge Risk-Based Management in Patients Undergoing High-Risk Elective Major Cancer Operations (PRS II)

Fox Chase Cancer Center

NCT05454280

RECRUITING Phase 3 854 participants

Spiritual Care or Psychotherapy Versus Palliative Care Alone in Patients With Non-Curative Malignancies

The Methodist Hospital Research Institute

NCT07290491

RECRUITING NA 800 participants

Occupational Cancer Screening in Firefighters: A Pilot Study Within the Inova Health System

Inova Health Care Services

NCT06931561

RECRUITING 725 participants

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

National Institute of Environmental Health Sciences (NIEHS)

NCT01143480

RECRUITING 700 participants

Met Non Small Cell Cancer Registry (MOMENT)

EMD Serono Research & Development Institute

NCT05376891

RECRUITING 700 participants

Immune Reconstitution in Stem Cell Transplant Recipients

University of Miami

NCT02129543

RECRUITING 700 participants

Evaluation of Late Effects and Natural History of Disease in Patients Treated With Radiotherapy

National Cancer Institute (NCI)

NCT00026650

RECRUITING 692 participants

Patient-Centered Assessment of Symptoms and Outcomes

National Center for Complementary and Integrative Health (NCCIH)

NCT03952624

RECRUITING NA 686 participants

Effectiveness of Central Oncology Navigation and the Use of an ORN

UNC Lineberger Comprehensive Cancer Center

NCT06618274

RECRUITING NA 650 participants

Modernizing Instructions to Improve Treatment Participation of Subjects During Their First Radiotherapy

University of Florida

NCT06246409

RECRUITING 600 participants

Autoimmunity After Checkpoint Blockade

Abramson Cancer Center at Penn Medicine

NCT04119713

RECRUITING 600 participants

Cannabis Use and Outcomes in Black and White Patients With Cancer

State University of New York at Buffalo

NCT06037681

RECRUITING Phase 1 575 participants

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Parabilis Medicines

NCT05919264

RECRUITING NA 530 participants

Re-Engaging AYA Survivors in Cancer-Related Healthcare

Children's Hospital of Philadelphia

NCT07138040

RECRUITING 520 participants

Understanding Patient Experience Among Asians at MD Anderson

M.D. Anderson Cancer Center

NCT06259253

RECRUITING NA 520 participants

NOURISH-T+: Promoting Healthy Eating and Exercise Behaviors

University of South Florida

NCT04656496

RECRUITING NA 515 participants

Implement and Test Visual Consent Template and Process

Washington University School of Medicine

NCT06804837

RECRUITING NA 510 participants

Addressing Tetrachloroethylene Exposure in an Impacted Community

Purdue University

NCT05819996

RECRUITING 500 participants

Ovarian Tissue Cryopreservation for Fertility Preservation

University of Pittsburgh

NCT05875155

RECRUITING 500 participants

Intra- and Inter-fraction Changes in Radiation Therapy

Medical College of Wisconsin

NCT02344121

RECRUITING 500 participants

Rare Tumors and Cancer Predisposition in Individuals and Families

National Cancer Institute (NCI)

NCT05350761

RECRUITING 500 participants

TEMPUS ARIES: A Biobank Registry Platform Study in Oncology

Tempus AI

NCT06207032

RECRUITING NA 500 participants

The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials

Eastern Cooperative Oncology Group

NCT06756607

RECRUITING 500 participants

UNC Childhood, Adolescent, and Young Adult Cancer Cohort

UNC Lineberger Comprehensive Cancer Center

NCT05096923

RECRUITING 500 participants

Multi-Cancer Detection Observational Cohort Study

Mayo Clinic

NCT06962995

RECRUITING 500 participants

Evaluation of Non-Invasive Assays for the Detection of Urothelial Cancer

Lahey Clinic

NCT00872495

RECRUITING 500 participants

Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System

RefleXion Medical

NCT05406167

RECRUITING 500 participants

From Screening to Support: A Multi-Method Analysis of HRSN Integration in Cancer Care

Thomas Jefferson University

NCT07352579

RECRUITING NA 459 participants

A New Psychotherapy Intervention for Older Cancer Patients

Memorial Sloan Kettering Cancer Center

NCT04452825

RECRUITING NA 456 participants

An Internet-based Program to Help Cancer Survivors Manage Pain

Wake Forest University Health Sciences

NCT04462302

RECRUITING 450 participants

IMmunotherapy: Prospective Assessment of Cannabis Treatment in Cancer

State University of New York at Buffalo

NCT06206941

RECRUITING NA 440 participants

Exploring Mindsets, Beliefs and Resilience Across the Cancer Experience

Stanford University

NCT06705218

RECRUITING 416 participants

Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform

Elephas

NCT05520099

RECRUITING NA 415 participants

Evaluation of Grief Therapy Approaches for Bereaved Parents

University of Miami

NCT05142605

RECRUITING Phase 3 402 participants

Study to Continue Treatment With Darolutamide in Patients Who Have Been Participating in Previous Darolutamide Studies Supported by Bayer

Bayer

NCT04464226

RECRUITING 400 participants

Risk Factors, Clinical Characteristics and Outcomes of Acute Infection With Coronavirus 2019 (COVID-19) In Children

St. Jude Children's Research Hospital

NCT04371315

RECRUITING Phase 1 400 participants

Investigation of Profile-related Evidence Determining Individualized Cancer Therapy for Patients With Aggressive Malignancies and Poor Prognoses

Medical College of Wisconsin

NCT05674825

RECRUITING NA 400 participants

Psycho-Spiritual Management for Patients With Advanced Cancer and Their Family Caregivers

M.D. Anderson Cancer Center

NCT06409065

RECRUITING Phase 3 390 participants

Abatacept in Immune Checkpoint Inhibitor Myocarditis

Massachusetts General Hospital

NCT05335928

RECRUITING Phase 1 386 participants

Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors

Conjupro Biotherapeutics

NCT07424547

RECRUITING NA 375 participants

Promoting Access, Resources and Treatment Through Novel and Equitable Solutions for Cancer Care

Case Comprehensive Cancer Center

NCT06481774

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Phase Distribution

PhaseTrial count
Phase 1 116
Phase 2 48
Phase 3 27
Phase 4 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Cancer right now

279 recruiting of 621 indexed (45% open).

Phase mix: 31 late (III/IV) vs 164 early (I/II) (early-phase heavy).

Top sponsor: M.D. Anderson Cancer Center (31 trials), 9 others listed. 50 shown below, recruiting first. #6 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Cancer?

PlainTrial tracks 621 US clinical trials for Cancer, of which 279 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.