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NCT05474846 · ClinicalTrials.gov registry record · Phase 2

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

A Phase 2 study of Depression and Cancer, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
188
Enrollment target
1
Study location

NCT05474846 is a Phase 2 study of Depression and Cancer that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 188 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05474846, a Phase 2 study of Depression and Cancer, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
188 participants
Enrollment target
1
Study location

Study Summary

To learn if Cognitive Behavior Therapy (called CBT), combined with either Bright Light Therapy (called BLT), methylphenidate, and/or melatonin, can help improve sleep and other related symptoms such as fatigue, anxiety, and depression in cancer patients. This is an investigational study. In this study, BLT, Methylphenidate and Melatonin will be compared to their placebos.

Conditions Studied

Depression Cancer Anxiety Sleep Fatigue

Interventions

  • DRUG Melatonin
  • DRUG Methylphenidate
  • OTHER Placebo for Melatonin

Study Locations (1)

Texas

  • MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 188 participants
Start Date 2022-11-21
Est. Completion 2027-02-28
Phase Phase 2

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05474846

The ClinicalTrials.gov registry entry for NCT05474846 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 188 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (76% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Depression appearing as the primary indexed condition, and to 3 interventions - of which Melatonin is the first listed.

NCT05474846 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT05474846 about?

NCT05474846 is a clinical study titled "Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer". To learn if Cognitive Behavior Therapy (called CBT), combined with either Bright Light Therapy (called BLT), methylphenidate, and/or melatonin, can help improve sleep and other related symptoms such as fatigue, anxiety, and depression in cancer patients. This is an investigational study. In this stu...

What is the current status of trial NCT05474846?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 188 participants. The study started on 2022-11-21. Estimated completion is 2027-02-28.

What conditions does trial NCT05474846 study?

This clinical trial studies the following conditions: Depression, Cancer, Anxiety, Sleep, Fatigue.

What interventions are being tested in trial NCT05474846?

The interventions under investigation include: Melatonin (DRUG), Methylphenidate (DRUG), Placebo for Melatonin (OTHER).

Who is sponsoring clinical trial NCT05474846?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05474846 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.