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NCT05674825 · ClinicalTrials.gov registry record · Phase 1

Investigation of Profile-related Evidence Determining Individualized Cancer Therapy for Patients With Aggressive Malignancies and Poor Prognoses

A Phase 1 study of Cancer, sponsored by Medical College of Wisconsin.

Recruiting
Registry status
Phase 1
Development phase
400
Enrollment target
1
Study location

NCT05674825 is a Phase 1 study of Cancer that is actively recruiting participants, run by Medical College of Wisconsin. The registered enrollment target is 400 participants, below the 3,490-participant average among 615 other Cancer trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05674825, a Phase 1 study of Cancer, is actively recruiting participants, sponsored by Medical College of Wisconsin.

RECRUITING
Registry status
Phase 1
Development phase
400 participants
Enrollment target
1
Study location

Study Summary

This is a prospective, open-label navigational investigation designed to evaluate the feasibility of using molecular profile-based evidence to determine individualized cancer therapy for patients with aggressive malignancies. This is a non-randomized, histology-agnostic trial. Although there will be a case mix of histologies, the investigators now know that individual histologies are composed of a heterogeneous mix of molecular alterations. It is not clear whether one case mix is better or worse than another. Thus, the investigators are testing a strategy of molecular matching that may apply across different cancers.

Conditions Studied

Interventions

  • DRUG Targeted agent
  • DRUG Standard of care agent

Study Locations (1)

Wisconsin

  • Froedtert Hospital & the Medical College of Wisconsin - Milwaukee

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2022-12-21
Est. Completion 2031-01
Phase Phase 1

Sponsor

Medical College of Wisconsin

447 total trials

What the Registry Record Tells You About NCT05674825

The ClinicalTrials.gov registry entry for NCT05674825 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,490-participant average among 615 other Cancer trials with a reported enrollment target (89% lower). The listed sponsor is Medical College of Wisconsin, which has 447 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Cancer appearing as the primary indexed condition, and to 2 interventions - of which Targeted agent is the first listed.

NCT05674825 reports 1 study location spanning 1 distinct geographic area - top geographies include Wisconsin.

Frequently Asked Questions

What is clinical trial NCT05674825 about?

NCT05674825 is a clinical study titled "Investigation of Profile-related Evidence Determining Individualized Cancer Therapy for Patients With Aggressive Malignancies and Poor Prognoses". This is a prospective, open-label navigational investigation designed to evaluate the feasibility of using molecular profile-based evidence to determine individualized cancer therapy for patients with aggressive malignancies. This is a non-randomized, histology-agnostic trial. Although there will be...

What is the current status of trial NCT05674825?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 400 participants. The study started on 2022-12-21. Estimated completion is 2031-01.

What conditions does trial NCT05674825 study?

This clinical trial studies the following conditions: Cancer.

What interventions are being tested in trial NCT05674825?

The interventions under investigation include: Targeted agent (DRUG), Standard of care agent (DRUG).

Who is sponsoring clinical trial NCT05674825?

This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05674825 being conducted?

This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.