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NCT05350761 · ClinicalTrials.gov registry record
Rare Tumors and Cancer Predisposition in Individuals and Families
A clinical trial of Cancer and Hereditary Neoplasms, sponsored by National Cancer Institute (NCI).
- Recruiting
- Registry status
- 500
- Enrollment target
- 2
- Study locations
NCT05350761: Recruiting study of Cancer and Hereditary Neoplasms, sponsored by National Cancer Institute (NCI).
NCT05350761 is a study of Cancer and Hereditary Neoplasms that is actively recruiting participants, run by National Cancer Institute (NCI). The registered enrollment target is 500 participants, below the 3,490-participant average among 615 other Cancer trials with a reported enrollment target (86% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05350761, a study of Cancer and Hereditary Neoplasms, is actively recruiting participants, sponsored by National Cancer Institute (NCI).
- RECRUITING
- Registry status
- 500 participants
- Enrollment target
- 2
- Study locations
Study Summary
Background: Some people may be prone to develop cancer for many reasons. Factors that affect their risk include the genes they inherit and the environment they live and work in. Researchers want to learn more about the natural history of cancer. Objective: To understand how genes and environmental factors can cause tumors and related conditions. Eligibility: People of any age who: Have tumors of an unusual type, pattern, or number Have a family member with a history of cancer Have been exposed to other factors that may increase their risk of cancer Design: This study does not involve treatment. Participants will answer questions about their personal and family medical history. They will give permission for researchers to see their medical records. Participants may be invited to the NIH Clinical Center for a physical exam. They may give samples including saliva, cheek cells, blood, urine, skin, and/or hair. Participants with cancer may give bone marrow. A needle will be used to remove a small sample of bone marrow from their hip bone. Participants may have a biopsy of their tumor. Participants may have other exams: Dental Ear, nose, and throat Eye Hearing Heart function and structure Participants with cancer may undergo more exams: A test of how much energy their body uses when resting A sleep study with a test that measures brain electrical activity. They will have sensors attached to their body while they sleep overnight in a lab. Imaging scans, such as CT, MRI, a test to measure how dense their bones are (DEXA), and ultrasound. Participants will have their genes tested. A counsellor will help them understand the results. Participants will be followed until at least 2035.
Primary Outcome
New cancer development or current health status
Conditions Studied
Study Locations (2)
Maryland
- National Institutes of Health Clinical Center - Bethesda
- NIH National Cancer Institute - Shady Grove - Rockville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 500 participants |
| Start Date | 2023-03-10 |
| Est. Completion | 2035-12-31 |
What NCT05350761 shows while recruiting
NCT05350761 is an observational study that tracks outcomes without assigning an intervention. The registered 500 participants enrollment target is mid-sized for trials with a published cap, below the 3,490-participant average among 615 other Cancer trials with a reported enrollment target (86% lower).
The record links to 4 conditions, with Cancer appearing as the primary indexed condition, and to 0 interventions.
NCT05350761 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05350761 about?
NCT05350761 is a clinical study titled "Rare Tumors and Cancer Predisposition in Individuals and Families". Background: Some people may be prone to develop cancer for many reasons. Factors that affect their risk include the genes they inherit and the environment they live and work in. Researchers want to learn more about the natural history of cancer. Objective: To understand how genes and environmenta...
What is the current status of trial NCT05350761?
This trial is currently recruiting. The enrollment target is 500 participants. The study started on 2023-03-10. Estimated completion is 2035-12-31.
What conditions does trial NCT05350761 study?
This clinical trial studies the following conditions: Cancer, Hereditary Neoplasms, Genetic Predisposition to Cancer, Environment.
Who is sponsoring clinical trial NCT05350761?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05350761 being conducted?
This trial has 2 study locations across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05350761's enrollment target sits among peer trials
500 122nd of 615 higher than 484 of 615 other Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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