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COMPLETED Phase 2

Bevacizumab Given With Either Anastrozole or Fulvestrant With Trastuzumab for Postmenopausal Metastatic Breast Cancer

NCT00405938 · View on ClinicalTrials.gov ↗

Study Summary

This is a phase II trial combining bevacizumab with either fulvestrant or anastrozole with trastuzumab in the treatment of metastatic breast cancer in postmenopausal women. It is hoped that these combinations will keep the cancer from growing and spreading further.

Interventions

  • DRUG Bevacizumab
  • DRUG Anastrozole
  • DRUG Fulvestrant

Study Locations (11)

Florida

  • Florida Cancer Specialists — Fort Myers
  • Integrated Community Oncology Network — Jacksonville
  • Florida Hospital Cancer Institute — Orlando

Georgia

  • Northeast Georgia Medical Center — Gainesville
  • Wellstar Cancer Research — Marietta

Tennessee

  • Chattanooga Oncology & Hematology Associates — Chattanooga
  • Tennessee Oncology, PLLC — Nashville

Kentucky

  • Graves-Gilbert Clinic — Bowling Green

Louisiana

  • Baton Rouge General Medical Center — Baton Rouge

Missouri

  • St. Louis Cancer Care — Chesterfield

Montana

  • Sletten Cancer Institute — Great Falls

Trial Details

FieldValue
Enrollment Target 79 participants
Start Date 2006-11
Est. Completion 2011-06
Phase Phase 2

Sponsor

SCRI Development Innovations

63 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00405938

The ClinicalTrials.gov registry entry for NCT00405938 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 79 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is SCRI Development Innovations, which has 63 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Breast Cancer appearing as the primary indexed condition, and to 3 interventions — of which Bevacizumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00405938 reports 11 study locations spanning 7 distinct geographic areas — top geographies include Florida, Georgia, Tennessee. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00405938 about?

NCT00405938 is a clinical study titled "Bevacizumab Given With Either Anastrozole or Fulvestrant With Trastuzumab for Postmenopausal Metastatic Breast Cancer". This is a phase II trial combining bevacizumab with either fulvestrant or anastrozole with trastuzumab in the treatment of metastatic breast cancer in postmenopausal women. It is hoped that these combinations will keep the cancer from growing and spreading further.

What is the current status of trial NCT00405938?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 79 participants. The study started on 2006-11. Estimated completion is 2011-06.

What conditions does trial NCT00405938 study?

This clinical trial studies the following conditions: Breast Cancer, Breast Neoplasms. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00405938?

The interventions under investigation include: Bevacizumab (DRUG), Anastrozole (DRUG), Fulvestrant (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00405938?

This trial is sponsored by SCRI Development Innovations, which has 63 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00405938 being conducted?

This trial has 11 study locations across Florida, Georgia, Kentucky, Louisiana, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial