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NCT02421978 · ClinicalTrials.gov registry record
Inflammation-Induced CNS Glutamate During Breast Cancer Treatment
A clinical trial of Breast Cancer, sponsored by Emory University.
- Completed
- Registry status
- 98
- Enrollment target
- 1
- Study location
NCT02421978: Completed study of Breast Cancer, sponsored by Emory University.
NCT02421978 is a study of Breast Cancer that has completed, run by Emory University. The registered enrollment target is 98 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02421978, a study of Breast Cancer, has completed, sponsored by Emory University.
- COMPLETED
- Registry status
- 98 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to try and provide data linking the impact of increased inflammatory cytokines as a result of chemotherapy and their relationship with increased levels of CNS glutamate and related behavioral and cognitive consequences in breast cancer patients. The investigators will use neuropsychiatric assessments, blood sampling and Magnetic Resonance Spectroscopy (MRS) to collect study data.
Primary Outcome
Single voxel MRS (Magnetic Resonance Spectroscopy) scans will be done to determine the glutamate levels in the dACC (dorsal anterior cingulate cortex), basal ganglia and hippocampus and the glutamate/ creatine (Glu/Cr) ratio will be calculated.MRS utilizes a magnetic field to look at magnetic nuclei, which absorb and re-emit electromagnetic energy in the presence of the magnetic field. By looking at the peaks in the resultant spectra the structure and concentration of metabolites can be determin
Conditions Studied
Study Locations (1)
Georgia
- Emory University Department of Psychiatry and Behavioral Sciences - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 98 participants |
| Start Date | 2015-05 |
| Est. Completion | 2018-05-29 |
What the finished NCT02421978 record still lists
NCT02421978 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 98 participants, a relatively small participant target, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 0 interventions.
NCT02421978 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT02421978 about?
NCT02421978 is a clinical study titled "Inflammation-Induced CNS Glutamate During Breast Cancer Treatment". The purpose of this study is to try and provide data linking the impact of increased inflammatory cytokines as a result of chemotherapy and their relationship with increased levels of CNS glutamate and related behavioral and cognitive consequences in breast cancer patients. The investigators will us...
What is the current status of trial NCT02421978?
This trial is currently completed. The enrollment target is 98 participants. The study started on 2015-05. Estimated completion is 2018-05-29.
What conditions does trial NCT02421978 study?
This clinical trial studies the following conditions: Breast Cancer.
Who is sponsoring clinical trial NCT02421978?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02421978 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02421978's enrollment target sits among peer trials
98 598th of 1224 higher than 622 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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