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Breast Cancer: early-phase trial registry
423 of 1,251 indexed Breast Cancer trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1 of 28,707 conditions by registered trial count.
1,251 US clinical trials · 423 currently recruiting · #1 of 28,707 conditions by registered trial count
Breast Cancer: 1,251 US clinical trials tracked, 423 recruiting.
Breast Cancer is the subject of 1,251 registered US clinical trials on ClinicalTrials.gov, 423 of them currently open to new participants. 120 are in Phase 3-4 (later-stage) and 491 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 98 of these trials.
Enrollment posture brief
Registry condition breast-cancer
OPEN 423 | RECR 34% | LATE 120 | EARLY 491 | RANK #1 | SPON 98
Volume-matched condition peers
Nearest open-share peer: Refractory Multiple Myeloma (34% recruiting · 68 trials)
Breast Cancer lists 423 open slots (34% of 1,251 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Breast Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Breast Cancer is recruiting below its size-band peers.
423 of 1,251 indexed trials (33.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Breast Cancer trials is spread across many organizations.
Memorial Sloan Kettering Cancer Center accounts for 98 of 1,251 trials (7.8%). 367 distinct sponsors appear on at least one study for this condition label.
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Typical Breast Cancer enrolment sits around 90 participants.
Median target enrolment is 90 among the 1,225 trials that report a genuine target (sentinel values excluded). 630 of those (51.4%) plan for fewer than 100 participants.
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Breast Cancer research is mostly interventional.
1,015 interventional and 236 observational studies make up this index (81.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
1,251 total, page 18 of 26
Compliance to a Hormone Therapy Regimen in Breast Cancer
Case Comprehensive Cancer Center
NCT00666822
A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine
Nektar Therapeutics
NCT02915744
Lynne Cohen Consortium Project: Multi-Center Database/Registry
M.D. Anderson Cancer Center
NCT00776958
Mometasone Furoate in Preventing Radiation Dermatitis in Patients Undergoing Radiation Therapy to the Breast or Chest Wall for Invasive Breast Cancer or Ductal Carcinoma in Situ
North Central Cancer Treatment Group
NCT00438659
Nonlinear Elasticity Mapping of Breast Masses
Mayo Clinic
NCT04863443
A Study of Accelerated 3 Fraction Photon,Proton or Brachytherapy for Early Invasive and Noninvasive Breast Ca
Mayo Clinic
NCT02453737
Methods in Education for Breast Cancer Genetics
National Cancer Institute (NCI)
NCT00001806
A Study of Prexasertib (LY2606368) With Chemotherapy or Targeted Agents in Participants With Advanced Cancer
Eli Lilly and Company
NCT02124148
Bevacizumab With or Without Cyclophosphamide and Methotrexate: A Pilot Study in Women With Operable Breast Cancer
Harold J. Burstein, MD, PhD
NCT00121134
SentiMag® Intraoperative Comparison in Breast Cancer
Endomagnetics
NCT02336737
XeNA Study - A Study of Xeloda (Capecitabine) in Patients With Invasive Breast Cancer
Hoffmann-La Roche
NCT00127933
Utilizing Social Contacts to Facilitate Mammogram Screening Among African American Women
Washington University School of Medicine
NCT05275361
A Study of Trastuzumab Emtansine (T-DM1) Sequentially With Anthracycline-based Chemotherapy, as Adjuvant or Neoadjuvant Therapy for Patients With Early Stage Herceptin (HER)2-positive Breast Cancer
Hoffmann-La Roche
NCT01196052
Exercise Program in Cancer and Cognition
University of Pittsburgh
NCT02793921
Genetic Risk Estimation of Breast Cancer Prior to Preventive Medication Uptake
Mayo Clinic
NCT02517593
Role of 3D Tomography in Breast Cancer
University of Rochester
NCT01090687
Healing Touch, Quality of Life, and Immunity During Breast Cancer Treatment
University of Iowa
NCT00565305
Intraoperative Pathway in DIEP Flap Breast Reconstruction
Beth Israel Deaconess Medical Center
NCT00543764
Vibro-Acoustography Imaging in Diagnosing Breast Masses in Women With a Breast Mass or Breast Cancer
Mayo Clinic
NCT00627614
The Impact of Lymphedema on Breast Cancer Survivors
University of California, San Francisco
NCT00769821
Cisplatin and Paclitaxel With or Without Everolimus in Treating Patients With Stage II or Stage III Breast Cancer
Vanderbilt-Ingram Cancer Center
NCT00930930
Phase II Randomized Trial Evaluating Neoadjuvant Therapy With Neratinib and/or Trastuzumab Followed by Postoperative Trastuzumab in Women With Locally Advanced HER2-positive Breast Cancer
NSABP Foundation
NCT01008150
Spectroscopy of Breast Tissue
Case Comprehensive Cancer Center
NCT00918216
PASSION - P Trial: Ph Adjusted Sulfur-Colloid, Sentinel Initiative ON Pain Trial
Walter Reed Army Medical Center
NCT00940199
Changes in Breast Density and Blood Hormone Levels in Postmenopausal Women Receiving Anastrozole or Exemestane for Breast Cancer
Alliance for Clinical Trials in Oncology
NCT00516698
A Study to Evaluate the Safety and Efficacy of Ipatasertib in Combination With Atezolizumab and Paclitaxel or Nab-Paclitaxel in Participants With Locally Advanced or Metastatic Triple-Negative Breast Cancer
Hoffmann-La Roche
NCT03800836
Multi-Media Imagery Program for Breast Cancer Patients (Phase II)
Mind Matters Research
NCT01034215
Cystic Breast Masses by Contrast Enhanced Ultrasound (CEUS)
University of Southern California
NCT02887937
PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery
Washington University School of Medicine
NCT03084536
Side Effects Involving the Heart in Women With Breast Cancer Receiving Doxorubicin and Trastuzumab
Vanderbilt University
NCT00875238
Myofascial Massage for Pain and Immobility Following Breast Cancer Surgery
MetroHealth Medical Center
NCT04233385
Contrast Enhanced Spectral Mammography vs. MRI for Breast Cancer Screening
Beth Israel Deaconess Medical Center
NCT03482557
A Prospective Longitudinal Breast Cancer Study
Fujirebio Diagnostics
NCT02270931
Routine Evaluation of the Social Determinants of Health in Oncology: User-centered Resource Coordination and Engagement
Dana-Farber Cancer Institute
NCT04879927
Novel Epothilone (BMS-247550) in Patients With Metastatic Breast Cancer (MBC)
R-Pharm
NCT00080262
Prevalence+Significance of Paraneoplastic Autoantibodies in Many Cancers
Memorial Sloan Kettering Cancer Center
NCT00608452
Enhancing Management of Chronic Pain and Symptoms Among Women Treated for Breast Cancer (Lymph-Flow)
NYU Langone Health
NCT02462226
Understanding the Value of Community Vital Signs in Primary Care
Virginia Commonwealth University
NCT02512835
Loss of Grip Strength, BMI, and Adjuvant Endocrine Therapy Breast Cancer
University of Michigan Rogel Cancer Center
NCT01896050
Stress, Diurnal Cortisol, and Breast Cancer Survival
Stanford University
NCT00226967
Breast MRI as a Preoperative Tool for DCIS
Memorial Sloan Kettering Cancer Center
NCT00605982
Facilitating Adjustment in Low Income Black Women With Breast Cancer
University of Miami
NCT02272335
A Study of Delivering a Mindfulness App Intervention to Accompany Supportive Care Among Women With Breast Cancer
The University of Texas Health Science Center at San Antonio
NCT02601794
Soy Protein Supplement In Treating Hot Flashes in Postmenopausal Women Receiving Tamoxifen for Breast Disease
Alliance for Clinical Trials in Oncology
NCT00031720
Using the Active Breathing Control Device to Reduce Radiation Side Effects to Critical Structures in Breast Cancer
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
NCT00328783
Trial of Drain Antisepsis After Tissue Expander Breast Reconstruction
Mayo Clinic
NCT01286168
Docetaxel in Treating Patients With Solid Tumors
Alliance for Clinical Trials in Oncology
NCT00003565
X-Ray Mammography Standard of Care Protocol
National Institutes of Health Clinical Center (CC)
NCT01052740
Letrozole in Treating Postmenopausal Women With Ductal Carcinoma in Situ
Alliance for Clinical Trials in Oncology
NCT01439711
Understanding Decision Making Processes for Undergoing Genetic Testing Among Women With Newly Diagnosed Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT01386411
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 235 |
| Phase 2 | 256 |
| Phase 3 | 100 |
| Phase 4 | 20 |
Top Sponsors
Named interventions
Most-linked intervention names on Breast Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Breast Cancer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Breast Cancer page
1,251 registered trials, 423 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 423 Breast Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Memorial Sloan Kettering Cancer Center sponsors the most Breast Cancer trials on record, review their full trial history before evaluating a specific study. See Memorial Sloan Kettering Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Breast Cancer condition card totals 1,251 registered trials; most-linked intervention Fulvestrant; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.