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NCT00217672 · ClinicalTrials.gov registry record · Phase 2

Docetaxel With Bevacizumab as First-Line Therapy in Treating Women With Stage IV Breast Cancer

A Phase 2 study of Breast Cancer, sponsored by Translational Oncology Research International.

Completed
Registry status
Phase 2
Development phase
76
Enrollment target
1
Study location

NCT00217672: Completed Phase 2 study of Breast Cancer, sponsored by Translational Oncology Research International.

NCT00217672 is a Phase 2 study of Breast Cancer that has completed, run by Translational Oncology Research International. The registered enrollment target is 76 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00217672, a Phase 2 study of Breast Cancer, has completed, sponsored by Translational Oncology Research International.

COMPLETED
Registry status
Phase 2
Development phase
76 participants
Enrollment target
1
Study location

Study Summary

RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of tumor cells by stopping blood flow to the tumor. It is not yet known whether giving docetaxel together with bevacizumab is more effective than docetaxel alone in treating breast cancer. PURPOSE: This randomized phase II trial is studying how well giving docetaxel together with bevacizumab works compared to docetaxel alone as first-line therapy in treating women with stage IV breast cancer.

Conditions Studied

Interventions

  • DRUG Docetaxel
  • BIOLOGICAL bevacizumab

Study Locations (1)

California

  • Jonsson Comprehensive Cancer Center at UCLA - Los Angeles

Trial Details

FieldValue
Enrollment Target 76 participants
Start Date 2005-05
Est. Completion 2010-11
Phase Phase 2

What the finished NCT00217672 record still lists

NCT00217672 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 76 participants, a relatively small participant target, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (97% lower).

The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Docetaxel is the first listed.

NCT00217672 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT00217672 about?

NCT00217672 is a clinical study titled "Docetaxel With Bevacizumab as First-Line Therapy in Treating Women With Stage IV Breast Cancer". RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab can block tumor growth in different ways. Some block the ability of tumor cell...

What is the current status of trial NCT00217672?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 76 participants. The study started on 2005-05. Estimated completion is 2010-11.

What conditions does trial NCT00217672 study?

This clinical trial studies the following conditions: Breast Cancer.

What interventions are being tested in trial NCT00217672?

The interventions under investigation include: Docetaxel (DRUG), bevacizumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT00217672?

This trial is sponsored by Translational Oncology Research International, which has 11 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00217672 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Breast Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00217672's enrollment target sits among peer trials

76 673rd of 1224 higher than 551 of 1,224 other Breast Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00217672, the US trial registry maintained by the National Library of Medicine. NCT00217672 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.