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NCT00217672 · ClinicalTrials.gov registry record · Phase 2

Docetaxel With Bevacizumab as First-Line Therapy in Treating Women With Stage IV Breast Cancer

A Phase 2 study of Breast Cancer, sponsored by Translational Oncology Research International.

Completed
Registry status
Phase 2
Development phase
76
Enrollment target
1
Study location

NCT00217672 is a Phase 2 study of Breast Cancer that has completed, run by Translational Oncology Research International. The registered enrollment target is 76 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00217672, a Phase 2 study of Breast Cancer, has completed, sponsored by Translational Oncology Research International.

COMPLETED
Registry status
Phase 2
Development phase
76 participants
Enrollment target
1
Study location

Study Summary

RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of tumor cells by stopping blood flow to the tumor. It is not yet known whether giving docetaxel together with bevacizumab is more effective than docetaxel alone in treating breast cancer. PURPOSE: This randomized phase II trial is studying how well giving docetaxel together with bevacizumab works compared to docetaxel alone as first-line therapy in treating women with stage IV breast cancer.

Conditions Studied

Interventions

  • DRUG Docetaxel
  • BIOLOGICAL bevacizumab

Study Locations (1)

California

  • Jonsson Comprehensive Cancer Center at UCLA - Los Angeles

Trial Details

FieldValue
Enrollment Target 76 participants
Start Date 2005-05
Est. Completion 2010-11
Phase Phase 2

What the Registry Record Tells You About NCT00217672

The ClinicalTrials.gov registry entry for NCT00217672 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 76 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (97% lower). The listed sponsor is Translational Oncology Research International, which has 11 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Docetaxel is the first listed.

NCT00217672 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT00217672 about?

NCT00217672 is a clinical study titled "Docetaxel With Bevacizumab as First-Line Therapy in Treating Women With Stage IV Breast Cancer". RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab can block tumor growth in different ways. Some block the ability of tumor cell...

What is the current status of trial NCT00217672?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 76 participants. The study started on 2005-05. Estimated completion is 2010-11.

What conditions does trial NCT00217672 study?

This clinical trial studies the following conditions: Breast Cancer.

What interventions are being tested in trial NCT00217672?

The interventions under investigation include: Docetaxel (DRUG), bevacizumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT00217672?

This trial is sponsored by Translational Oncology Research International, which has 11 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00217672 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.