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ClinicalTrials.gov 423 recruiting now early-phase tilt #1 of 28,963 conditions

Breast Cancer: early-phase trial registry

423 of 1,251 indexed Breast Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1 of 28,963 conditions by registered trial count.

1,251 US clinical trials · 423 currently recruiting · #1 of 28,963 conditions by registered trial count

Breast Cancer: 1,251 US clinical trials tracked, 423 recruiting.

Breast Cancer is the subject of 1,251 registered US clinical trials on ClinicalTrials.gov, 423 of them currently open to new participants. 120 are in Phase 3-4 (later-stage) and 491 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 98 of these trials.

Open enrollment, early-phase tilt

Breast Cancer has 1,251 registered US clinical trials, 423 of them open to new participants right now, about 34% of the total.

423
recruiting participants now
34%
of trials open to enrollment
120
in Phase 3-4 (later-stage)
98
top sponsor: Memorial Sloan Kettering Cancer Center

Corpus placement: #1 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Breast Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Breast Cancer is recruiting below its size-band peers.

    423 of 1,251 indexed trials (33.8%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Breast Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 98 of 1,251 trials (7.8%). 367 distinct sponsors appear on at least one study for this condition label.

  3. Typical Breast Cancer enrolment sits around 90 participants.

    Median target enrolment is 90 among the 1,225 trials that report a genuine target (sentinel values excluded). 630 of those (51.4%) plan for fewer than 100 participants.

  4. Breast Cancer research is mostly interventional.

    1,015 interventional and 236 observational studies make up this index (81.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1235Phase 2256Phase 3100Phase 420

Open and recent trials

1,251 total, page 16 of 26

COMPLETED 2,472 participants

Cancer Prevention and Treatment Demonstration for Ethnic and Racial Minorities

M.D. Anderson Cancer Center

NCT00453661

COMPLETED Phase 3 2,411 participants

Chemotherapy in Treating Women With Breast Cancer That Can Be Surgically Removed

NSABP Foundation

NCT00002707

COMPLETED NA 2,241 participants

Helping Women Stay Up-To-Date With Cancer Screening By Using a Prevention Care Manager or Usual Care

Dartmouth-Hitchcock Medical Center

NCT00477646

COMPLETED 2,201 participants

Changes in Breast Density and Breast Cancer Risk in Women With Breast Cancer and in Healthy Women

Case Comprehensive Cancer Center

NCT00445445

COMPLETED NA 1,800 participants

Multimedia Educational Program for Patients With Early-Stage Prostate Cancer or Breast Cancer

University of Colorado, Denver

NCT00830635

COMPLETED Phase 3 1,598 participants

Exemestane in Treating Postmenopausal Women With Resected Stage I, Stage II, or Stage IIIA Breast Cancer Who Have Completed 5 Years of Tamoxifen

NSABP Foundation

NCT00016432

COMPLETED Phase 3 1,491 participants

Docetaxel in Node Positive Adjuvant Breast Cancer

Sanofi

NCT00688740

COMPLETED 1,452 participants

Cancer Screening and Prevention Program for High Risk Women

NYU Langone Health

NCT00849199

COMPLETED 1,436 participants

Implementing Systematic Distress Screening in Breast Cancer

Kaiser Permanente

NCT02941614

COMPLETED 1,429 participants

PRospective REgistry of Advanced Stage CancER (PREFER) Patients to Assess Prevalence of Actionable Biomarkers and Driver Mutations to Address Disparities in Precision Medicine

Labcorp Corporation of America Holdings

NCT05697198

COMPLETED NA 1,342 participants

Evaluation of Mailers Promoting Mammogram Screening

Geisinger Clinic

NCT04555902

COMPLETED NA 1,290 participants

Interventions to Increase Screening by Breast Cancer Survivors and Their High Risk Female Relatives

University of Michigan

NCT01612338

COMPLETED NA 1,267 participants

Patient Navigator Project

H. Lee Moffitt Cancer Center and Research Institute

NCT00375024

COMPLETED Phase 3 1,250 participants

A Study of Palbociclib in Addition to Standard Endocrine Treatment in Hormone Receptor Positive Her2 Normal Patients With Residual Disease After Neoadjuvant Chemotherapy and Surgery

GBG Forschungs

NCT01864746

COMPLETED NA 1,235 participants

Breast Cancer Risk Reduction: A Patient Doctor Intervention

University of California, San Francisco

NCT01830933

COMPLETED 1,232 participants

Acquisition of Breast Mammography Images

Fujifilm Medical Systems USA

NCT02156258

COMPLETED Phase 3 1,221 participants

Epothilone (Ixabepilone) Plus Capecitabine Versus Capecitabine Alone in Patients With Advanced Breast Cancer

R-Pharm

NCT00082433

COMPLETED NA 1,183 participants

Evaluation of a 3-D Tomosynthesis Mammography System Used in Conjunction With Conventional 2-D Digital Mammography

Hologic

NCT00754598

COMPLETED 1,136 participants

Scripps Polster Breast Care Center Investigational GeneBank

Scripps Translational Science Institute

NCT00945464

COMPLETED 1,118 participants

Correlation of Menstrual Cycle Phase at Time of Primary Surgery With 5-Year Disease-Free Survival in Women With Stage I or Stage II Breast Cancer

Alliance for Clinical Trials in Oncology

NCT00002762

COMPLETED NA 1,071 participants

BRAVE Strategy - Breast Cancer Risk Assessment -achieVing Equity

Vanderbilt University Medical Center

NCT05051631

COMPLETED NA 1,053 participants

Effectiveness of Lay Navigators in Meeting Cancer Patients' Non-Clinical Needs: A Pilot Study

Stanford University

NCT03245788

COMPLETED NA 1,007 participants

Magnetic Resonance Imaging in Women Recently Diagnosed With Unilateral Breast Cancer

American College of Radiology Imaging Network

NCT00058058

COMPLETED 1,000 participants

Genetic Susceptibility to Radiation-Induced Skin Reactions in Racial/Ethnic Groups of Patients With Breast Cancer

Wake Forest University Health Sciences

NCT01407770

COMPLETED 977 participants

Outcomes of a Deep Inferior Epigastric Perforator Flap Program

Beth Israel Deaconess Medical Center

NCT00543907

COMPLETED 938 participants

Breast Cancers: Risk Factors Among Mexican Women in Mexico, Mexican-American and African-American Women in the U.S.

M.D. Anderson Cancer Center

NCT00837499

COMPLETED 873 participants

International Breast Cancer Biomarker,Standard of Care and Real World Outcomes Study

AstraZeneca

NCT03078036

COMPLETED Phase 3 807 participants

Efficacy and Safety Study of EG12014 Compared With Herceptin in Subjects With HER2 Positive Early Breast Cancer

EirGenix

NCT03433313

COMPLETED NA 764 participants

Evaluation of the Efficacy of Digital Breast Tomosynthesis Imaging

Siemens Medical Solutions USA - CSG

NCT01373671

COMPLETED Phase 2 756 participants

Surgery to Remove the Sentinel Lymph Node and Axillary Lymph Nodes After Chemotherapy in Treating Women With Stage II, Stage IIIA, or Stage IIIB Breast Cancer

Alliance for Clinical Trials in Oncology

NCT00881361

COMPLETED Phase 3 722 participants

Paclitaxel With or Without Bevacizumab in Treating Patients With Locally Recurrent or Metastatic Breast Cancer

Eastern Cooperative Oncology Group

NCT00028990

COMPLETED Phase 3 652 participants

Chemotherapy and Lapatinib or Trastuzumab in Treating Women With HER2/Neu-Positive Metastatic Breast Cancer

Novartis Pharmaceuticals

NCT00667251

COMPLETED Phase 3 605 participants

Lymph Node Removal in Treating Women Who Have Stage I or Stage IIA Breast Cancer

Alliance for Clinical Trials in Oncology

NCT00003855

COMPLETED Phase 3 602 participants

A Study of Trastuzumab Emtansine in Comparison With Treatment of Physician's Choice in Participants With HER2-positive Breast Cancer Who Have Received at Least Two Prior Regimens of HER2-directed Therapy

Hoffmann-La Roche

NCT01419197

COMPLETED 550 participants

Molecular Genetic Basis of Invasive Breast Cancer Risk Associated With Lobular Carcinoma in Situ

Memorial Sloan Kettering Cancer Center

NCT00581750

COMPLETED Phase 3 529 participants

Trial of Sacituzumab Govitecan in Participants With Refractory/Relapsed Metastatic Triple-Negative Breast Cancer (TNBC)

Gilead Sciences

NCT02574455

COMPLETED NA 516 participants

Kin KeeperSM: Reducing Disparities Through Cancer Literacy and Screening

Michigan State University

NCT01910350

COMPLETED 500 participants

Expanded Breast Cancer Registry and Tissue Repository

New Mexico Cancer Research Alliance

NCT00322894

COMPLETED NA 500 participants

Study of Survivorship Care Plans and Outcomes in Underserved Breast Cancer Survivors

Jonsson Comprehensive Cancer Center

NCT01627366

COMPLETED Phase 2 493 participants

Adj TC + Herceptin Early Stage Breast Cancer

US Oncology Research

NCT00493649

COMPLETED Phase 2 479 participants

Study Evaluating Neratinib Plus Paclitaxel VS Trastuzumab Plus Paclitaxel In ErbB-2 Positive Advanced Breast Cancer

Puma Biotechnology

NCT00915018

COMPLETED Phase 3 464 participants

Prasterone (Dehydroepiandrosterone) in Treating Postmenopausal Cancer Survivors With Vaginal Symptoms

Alliance for Clinical Trials in Oncology

NCT01376349

COMPLETED Phase 3 454 participants

A Study To Evaluate the Efficacy and Safety Of Atezolizumab or Placebo in Combination With Neoadjuvant Doxorubicin + Cyclophosphamide Followed By Paclitaxel + Trastuzumab + Pertuzumab In Early Her2-Positive Breast Cancer

Hoffmann-La Roche

NCT03726879

COMPLETED NA 451 participants

Reflexology: An Intervention for Advanced Breast Cancer

Michigan State University

NCT01577420

COMPLETED Phase 3 439 participants

Zoledronate, Calcium, and Vitamin D in Preventing Bone Loss in Women Receiving Adjuvant Chemotherapy for Breast Cancer

Alliance for Clinical Trials in Oncology

NCT00022087

COMPLETED Phase 3 433 participants

Prospective Trial of Two Prone Breast Radiotherapy Techniques With Randomization to Concurrent Versus Weekly Boost

NYU Langone Health

NCT01591811

COMPLETED Phase 2 416 participants

A Study of the Experimental Drug BKM120 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast Cancer, With or Without PI3K Activation

Novartis Pharmaceuticals

NCT01572727

COMPLETED Phase 3 406 participants

Investigation of Novel Surgical Imaging for Tumor Excision

Lumicell

NCT03686215

COMPLETED 401 participants

Cone Beam Computed Tomography for Breast Imaging

Koning Corporation

NCT01107860

COMPLETED Phase 2 384 participants

Study to Assess Effectiveness of Giving Combination of Standard Chemotherapy Drugs Versus Combination of Standard Chemotherapy and New Drug Ixabepilone When Given Before Surgical Removal of Early Stage Breast Cancer

Bristol-Myers Squibb

NCT00455533

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Phase Distribution

PhaseTrial count
Phase 1 235
Phase 2 256
Phase 3 100
Phase 4 20

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Breast Cancer right now

423 recruiting of 1,251 indexed (34% open).

Phase mix: 120 late (III/IV) vs 491 early (I/II) (early-phase heavy).

Top sponsor: Memorial Sloan Kettering Cancer Center (98 trials), 9 others listed. 50 shown below, recruiting first. #1 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Breast Cancer?

PlainTrial tracks 1,251 US clinical trials for Breast Cancer, of which 423 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Breast Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.