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NCT00881361 · ClinicalTrials.gov registry record · Phase 2

Surgery to Remove the Sentinel Lymph Node and Axillary Lymph Nodes After Chemotherapy in Treating Women With Stage II, Stage IIIA, or Stage IIIB Breast Cancer

A Phase 2 study of Breast Cancer, sponsored by Alliance for Clinical Trials in Oncology.

Completed
Registry status
Phase 2
Development phase
756
Enrollment target
20
Study locations

NCT00881361 is a Phase 2 study of Breast Cancer that has completed, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 756 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (73% lower). The trial reports 20 study locations across 4 states.

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The verdict

NCT00881361, a Phase 2 study of Breast Cancer, has completed, sponsored by Alliance for Clinical Trials in Oncology.

COMPLETED
Registry status
Phase 2
Development phase
756 participants
Enrollment target
20
Study locations

Study Summary

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. PURPOSE: This phase II trial is studying surgery to remove the sentinel lymph node and axillary lymph nodes after chemotherapy in treating women with stage II, stage IIIA, or stage IIIB breast cancer.

Conditions Studied

Interventions

  • PROCEDURE therapeutic conventional surgery
  • DRUG systemic chemotherapy
  • PROCEDURE axillary lymph node dissection
  • PROCEDURE neoadjuvant therapy
  • PROCEDURE sentinel lymph node biopsy

Study Locations (20)

California

  • East Bay Radiation Oncology Center - Castro Valley
  • Valley Medical Oncology Consultants - Castro Valley - Castro Valley
  • Cancer Care Center at John Muir Health - Concord Campus - Concord
  • City of Hope Comprehensive Cancer Center - Duarte
  • Valley Medical Oncology - Fremont
  • Todd Cancer Institute at Long Beach Memorial Medical Center - Long Beach
  • USC/Norris Comprehensive Cancer Center and Hospital - Los Angeles
  • Contra Costa Regional Medical Center - Martinez
  • Community Hospital of the Monterey Peninsula Comprehensive Cancer Center - Monterey
  • Camino Medical Group - Treatment Center - Mountain View
  • El Camino Hospital Cancer Center - Mountain View
  • Highland General Hospital - Oakland
  • Bay Area Breast Surgeons, Incorporated - Oakland
  • CCOP - Bay Area Tumor Institute - Oakland
  • Larry G Strieff MD Medical Corporation - Oakland
  • Tom K Lee, Incorporated - Oakland
  • Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center - Orange

Alabama

  • University of South Alabama Mitchell Cancer Institute - Mobile

Alaska

  • Providence Cancer Center - Anchorage

Arkansas

  • Arkansas Cancer Research Center at University of Arkansas for Medical Sciences - Little Rock

Trial Details

FieldValue
Enrollment Target 756 participants
Start Date 2009-07
Est. Completion 2023-04-15
Phase Phase 2

What the Registry Record Tells You About NCT00881361

The ClinicalTrials.gov registry entry for NCT00881361 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 756 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (73% lower). The listed sponsor is Alliance for Clinical Trials in Oncology, which has 446 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 5 interventions - of which therapeutic conventional surgery is the first listed.

NCT00881361 reports 20 study locations spanning 4 distinct geographic areas - top geographies include California, Alabama, Alaska.

Frequently Asked Questions

What is clinical trial NCT00881361 about?

NCT00881361 is a clinical study titled "Surgery to Remove the Sentinel Lymph Node and Axillary Lymph Nodes After Chemotherapy in Treating Women With Stage II, Stage IIIA, or Stage IIIB Breast Cancer". RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. PURPOSE: This...

What is the current status of trial NCT00881361?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 756 participants. The study started on 2009-07. Estimated completion is 2023-04-15.

What conditions does trial NCT00881361 study?

This clinical trial studies the following conditions: Breast Cancer.

What interventions are being tested in trial NCT00881361?

The interventions under investigation include: therapeutic conventional surgery (PROCEDURE), systemic chemotherapy (DRUG), axillary lymph node dissection (PROCEDURE), neoadjuvant therapy (PROCEDURE), sentinel lymph node biopsy (PROCEDURE).

Who is sponsoring clinical trial NCT00881361?

This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00881361 being conducted?

This trial has 20 study locations across Alabama, Alaska, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.