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Chemotherapy in Treating Women With Breast Cancer That Can Be Surgically Removed
NCT00002707 · View on ClinicalTrials.gov ↗
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if chemotherapy given before surgery is more effective with or without docetaxel given before or after surgery for breast cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of chemotherapy using doxorubicin and cyclophosphamide with or without docetaxel in treating women who have stage II or stage III breast cancer.
Conditions Studied
Interventions
- DRUG Cyclophosphamide
- DRUG Docetaxel
- DRUG Doxorubicin
- DRUG Tamoxifen
Study Locations (20)
California
- Sutter Health Western Division Cancer Research Group — Greenbrae
- Loma Linda University Medical Center — Loma Linda
- Saint Mary Medical Center - Long Beach — Long Beach
- Beckman Research Institute, City of Hope — Los Angeles
- CCOP - Bay Area Tumor Institute — Oakland
- Chao Family Comprehensive Cancer Center — Orange
- Comprehensive Cancer Centers of the Desert — Palm Springs
- Kaiser Permanente-Southern California Permanente Medical Group — San Diego
- Catholic Healthcare West - Westbay Region — San Francisco
- CCOP - Santa Rosa Memorial Hospital — Santa Rosa
- Kaiser Permanente Medical Center - Vallejo — Vallejo
Colorado
- CCOP - Colorado Cancer Research Program, Inc. — Denver
- University of Colorado Cancer Center — Denver
Connecticut
- University of Connecticut Health Center — Farmington
- Hartford Hospital — Hartford
Alabama
- Huntsville Hospital System — Huntsville
Arizona
- CCOP - Greater Phoenix — Phoenix
Delaware
- CCOP - Christiana Care Health Services — Wilmington
District of Columbia
- George Washington University Cancer Center — Washington D.C.
Florida
- Halifax Medical Center — Daytona Beach
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,411 participants |
| Start Date | 1995-12 |
| Est. Completion | 2010-02 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00002707
The ClinicalTrials.gov registry entry for NCT00002707 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 2,411 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is NSABP Foundation, which has 11 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 4 interventions — of which Cyclophosphamide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00002707 reports 20 study locations spanning 8 distinct geographic areas — top geographies include California, Colorado, Connecticut. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00002707 about?
NCT00002707 is a clinical study titled "Chemotherapy in Treating Women With Breast Cancer That Can Be Surgically Removed". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if chemotherapy given before surgery is more effective with or without docetaxel given before or after surgery for breast cancer. PURPOSE: Randomized phase III...
What is the current status of trial NCT00002707?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 2,411 participants. The study started on 1995-12. Estimated completion is 2010-02.
What conditions does trial NCT00002707 study?
This clinical trial studies the following conditions: Breast Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00002707?
The interventions under investigation include: Cyclophosphamide (DRUG), Docetaxel (DRUG), Doxorubicin (DRUG), Tamoxifen (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00002707?
This trial is sponsored by NSABP Foundation, which has 11 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00002707 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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