Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Breast Cancer: early-phase trial registry
423 of 1,251 indexed Breast Cancer trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1 of 28,707 conditions by registered trial count.
1,251 US clinical trials · 423 currently recruiting · #1 of 28,707 conditions by registered trial count
Breast Cancer: 1,251 US clinical trials tracked, 423 recruiting.
Breast Cancer is the subject of 1,251 registered US clinical trials on ClinicalTrials.gov, 423 of them currently open to new participants. 120 are in Phase 3-4 (later-stage) and 491 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 98 of these trials.
Enrollment posture brief
Registry condition breast-cancer
OPEN 423 | RECR 34% | LATE 120 | EARLY 491 | RANK #1 | SPON 98
Volume-matched condition peers
Nearest open-share peer: Refractory Multiple Myeloma (34% recruiting · 68 trials)
Breast Cancer lists 423 open slots (34% of 1,251 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Breast Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Breast Cancer is recruiting below its size-band peers.
423 of 1,251 indexed trials (33.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Breast Cancer trials is spread across many organizations.
Memorial Sloan Kettering Cancer Center accounts for 98 of 1,251 trials (7.8%). 367 distinct sponsors appear on at least one study for this condition label.
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Typical Breast Cancer enrolment sits around 90 participants.
Median target enrolment is 90 among the 1,225 trials that report a genuine target (sentinel values excluded). 630 of those (51.4%) plan for fewer than 100 participants.
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Breast Cancer research is mostly interventional.
1,015 interventional and 236 observational studies make up this index (81.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
1,251 total, page 17 of 26
Four Conversations RCT
Duke University
NCT02944344
Joint Pain and Medication Adherence in Postmenopausal Women Receiving Aromatase Inhibitors
Vanderbilt University Medical Center
NCT00954564
Evaluation of the Efficacy of National Cancer Institute's Facing Forward Booklet in the Cancer Community Setting
Fox Chase Cancer Center
NCT01440855
Collection of Patient-Reported Symptoms and Performance Status Via the Internet
Alliance for Clinical Trials in Oncology
NCT00417040
Developing and Evaluating Culturally Relevant Interventions to Improve Breast Cancer Screening
Johns Hopkins Bloomberg School of Public Health
NCT05665660
Screening in Myocardial Perfusion Patients
Mayo Clinic
NCT00943241
Soy Protein and Breast Cancer Risk Reduction
The University of Texas Medical Branch, Galveston
NCT00204477
Compare Outcomes Between Two Acellular Dermal Matrices
Washington University School of Medicine
NCT02891759
Studying Biomarkers in Nipple Fluid, Urine, and Blood Samples From Women With Newly Diagnosed Ductal Carcinoma In Situ or Stage I or Stage II Breast Cancer and in Women at Risk of Developing Breast Cancer
Mayo Clinic
NCT00897208
A Phase II Study of Everolimus in Combination With Exemestane Versus Everolimus Alone Versus Capecitabine in Advance Breast Cancer.
Novartis Pharmaceuticals
NCT01783444
Phase III Study Comparing the Efficacy and Safety of LA-EP2006 and Peg-Filgrastim
Sandoz
NCT01516736
OPTimizing Treatment Focused Genetic Testing IN Cancer
Dana-Farber Cancer Institute
NCT04066361
Physical Activity Promotion in Cancer Follow-Up Care
The Miriam Hospital
NCT00230711
Redes III Patient Navigator Qol Study
The University of Texas Health Science Center at San Antonio
NCT02275754
Vitamin D and Breast Cancer Biomarkers in Female Patients
Alliance for Clinical Trials in Oncology
NCT01224678
S1202: Duloxetine Hydrochloride for Muscle/Joint Pain in Early-Stage Breast Cancer Receiving Hormone Therapy
SWOG Cancer Research Network
NCT01598298
A Multi-Reader Multi-Case Pivotal Trial
Fujifilm Medical Systems USA
NCT02692209
Acupressure for Persistent Cancer Related Fatigue
University of Michigan
NCT01281904
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Stage II or Stage IIIA Breast Cancer
Fred Hutchinson Cancer Center
NCT00003972
An Observational Pilot Study Evaluating the Feasibility of Conducting Genome-Wide Association Studies Utilizing Subject Provided Information in Subjects With Locally Recurrent or MBC, MCRC, MNSCLC, RGBM or MRCC Treated With Avastin (Bevacizumab) (InVite)
Genentech
NCT01598597
Decision Support for BRCA Testing in Ethnically Diverse Women
Columbia University
NCT03470402
Randomized Clinical Trial to Evaluate the Predictive Accuracy of a Gene Expression for Stage I-II Breast Cancer
M.D. Anderson Cancer Center
NCT00336791
Evaluation of BIS for Quantification of Lymphedema
Massachusetts General Hospital
NCT01544335
Investigating the Impact of Tamoxifen Therapy on Ovarian Aging
University of California, San Francisco
NCT01384526
Multi-Reader, Multi-Case, Cross-Over, Retrospective Study to Evaluate Effectiveness of Lunit INSIGHT DBT
Lunit
NCT05716958
Trastuzumab in Combination With Vinorelbine or Taxane-Based Chemotherapy in Patients With Metastatic Breast Cancer
Dana-Farber Cancer Institute
NCT00146549
Luteal vs Follicular Surgical Oophorectomy and Tamoxifen in Premenopausal Women With Metastatic Hormone Receptor Positive Breast Cancer
International Breast Cancer Research Foundation
NCT00293540
Biomarkers in Blood Samples From Older Breast Cancer Survivors
UNC Lineberger Comprehensive Cancer Center
NCT01138345
Standard Genetic Counseling With or Without a Decision Guide in Improving Communication Between Mothers Undergoing BRCA1/2 Testing and Their Minor-Age Children
Georgetown University
NCT00685256
Epidemiological Analysis of Vitamin D and Breast Cancer Risk in Saudi Arabian Women
University of Arizona
NCT01817231
Neuropathic Pain in Survivors of Breast Cancer
M.D. Anderson Cancer Center
NCT00535067
A Study of LY2880070 in Participants With Advanced or Metastatic Cancer
Esperas Pharma
NCT02632448
EGb761 in Maintaining Mental Clarity in Women Receiving Chemotherapy for Newly Diagnosed Breast Cancer
Alliance for Clinical Trials in Oncology
NCT00046891
Quantitative Subharmonic Breast Imaging
Thomas Jefferson University
NCT01490892
S0800, Nab-Paclitaxel, Doxorubicin, Cyclophosphamide, and Pegfilgrastim With or Without Bevacizumab in Treating Women With Inflammatory or Locally Advanced Breast Cancer
SWOG Cancer Research Network
NCT00856492
Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
Alliance for Clinical Trials in Oncology
NCT00377156
Optical Spectroscopy During Breast Cancer Surgery and Core Needle Biopsy
Duke University
NCT00734838
Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation in Treating Women With Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute
NCT00005798
Prospective Observational Study Evaluating Treatment Decision Impact of Prosigna® in Early Stage Breast Cancer Patients
NanoString Technologies
NCT02625935
Infrared Imaging (Breast Scan IR) for Early Breast Cancer Detection
Weill Medical College of Cornell University
NCT00195026
Delayed-Immediate Breast Reconstruction
M.D. Anderson Cancer Center
NCT00473122
A First-in-Human Study of D-0502 Alone and in Combination With Palbociclib in Women With Advanced or Metastatic ER-Positive and HER2-Negative Breast Cancer
InventisBio Co.
NCT03471663
To Enhance Breast Cancer Survivorship of Asian Americans
Emory University
NCT02803593
Southeast Asian Women's Health Project
Ohio State University
NCT04086771
A Trial of Paclitaxel and Bevacizumab vs. Gemcitabine, Paclitaxel, and Bevacizumab in Advanced Breast Cancer
Eli Lilly and Company
NCT00320541
Pre-biopsy With Dynamic Acquisitions
Mayo Clinic
NCT00943644
Combined Digital X-ray and Ultrasound Technique for Improved Detection and Characterization of Breast Lesions
University of Michigan
NCT00721435
Menopausal Symptoms in Women With Breast Cancer or At High Risk of Breast Cancer Treated on Another Clinical Trial
Case Comprehensive Cancer Center
NCT00666913
Exercise Programs in Healthy Young Women at Increased Risk of Developing Breast Cancer
Abramson Cancer Center at Penn Medicine
NCT00892515
SWOG-9342 Chemotherapy in Treating Women Enrolled in the SWOG-8897 Clinical Trial
SWOG Cancer Research Network
NCT00002900
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 235 |
| Phase 2 | 256 |
| Phase 3 | 100 |
| Phase 4 | 20 |
Top Sponsors
Named interventions
Most-linked intervention names on Breast Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Breast Cancer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Breast Cancer page
1,251 registered trials, 423 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 423 Breast Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Memorial Sloan Kettering Cancer Center sponsors the most Breast Cancer trials on record, review their full trial history before evaluating a specific study. See Memorial Sloan Kettering Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Breast Cancer condition card totals 1,251 registered trials; most-linked intervention Fulvestrant; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.