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NCT00945464 · ClinicalTrials.gov registry record
Scripps Polster Breast Care Center Investigational GeneBank
A clinical trial of Breast Cancer, sponsored by Scripps Translational Science Institute.
- Completed
- Registry status
- 1,136
- Enrollment target
- 1
- Study location
NCT00945464 is a study of Breast Cancer that has completed, run by Scripps Translational Science Institute. The registered enrollment target is 1,136 participants, below the 2,802-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (59% lower). The trial reports 1 study location across 1 state.
The verdict
NCT00945464, a study of Breast Cancer, has completed, sponsored by Scripps Translational Science Institute.
- COMPLETED
- Registry status
- 1,136 participants
- Enrollment target
- 1
- Study location
Study Summary
Breast cancer is a disease of complex origin with a strong genetic component. The incidence of breast cancer is very high in monozygotic twins of patients, and it is thought that a high proportion and perhaps the majority of breast cancers arise in a small number of genetically susceptible women. Recent studies in human genetics have discovered several intervals in the human genome containing inherited variants that are statistically associated with the propensity to develop breast cancer. The investigators plan to use this knowledge to design a genetic screening test to guide recommendations for breast cancer screening with mammography. If the small group of genetically susceptible women can be identified, more effective breast cancer screening strategies can be implemented. In contrast, a very large proportion of women who undergo yearly mammography are at exceptionally low risk from a genetic perspective. Using genomic guidance could eventually reconfigure the most efficacious strategy to screen women for early detection of breast cancer. By developing a genetic screening panel based on genetic markers for breast cancer, the investigators will be able to more accurately determine a woman's individual risk for developing breast cancer.
Conditions Studied
Interventions
- OTHER Blood/saliva samples, historic breast imaging
Study Locations (1)
California
- Scripps Polster Breast Care Center - La Jolla
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,136 participants |
| Start Date | 2008-07 |
| Est. Completion | 2015-06 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00945464
The ClinicalTrials.gov registry entry for NCT00945464 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 1,136 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,802-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (59% lower). The listed sponsor is Scripps Translational Science Institute, which has 41 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which Blood/saliva samples, historic breast imaging is the first listed.
NCT00945464 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT00945464 about?
NCT00945464 is a clinical study titled "Scripps Polster Breast Care Center Investigational GeneBank". Breast cancer is a disease of complex origin with a strong genetic component. The incidence of breast cancer is very high in monozygotic twins of patients, and it is thought that a high proportion and perhaps the majority of breast cancers arise in a small number of genetically susceptible women. Re...
What is the current status of trial NCT00945464?
This trial is currently completed. The enrollment target is 1,136 participants. The study started on 2008-07. Estimated completion is 2015-06.
What conditions does trial NCT00945464 study?
This clinical trial studies the following conditions: Breast Cancer.
What interventions are being tested in trial NCT00945464?
The interventions under investigation include: Blood/saliva samples, historic breast imaging (OTHER).
Who is sponsoring clinical trial NCT00945464?
This trial is sponsored by Scripps Translational Science Institute, which has 41 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00945464 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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