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NCT00028990 · ClinicalTrials.gov registry record · Phase 3
Paclitaxel With or Without Bevacizumab in Treating Patients With Locally Recurrent or Metastatic Breast Cancer
A Phase 3 study of Breast Cancer, sponsored by Eastern Cooperative Oncology Group.
- Completed
- Registry status
- Phase 3
- Development phase
- 722
- Enrollment target
- 20
- Study locations
NCT00028990: Completed Phase 3 study of Breast Cancer, sponsored by Eastern Cooperative Oncology Group.
NCT00028990 is a Phase 3 study of Breast Cancer that has completed, run by Eastern Cooperative Oncology Group. The registered enrollment target is 722 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (74% lower). The trial reports 20 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00028990, a Phase 3 study of Breast Cancer, has completed, sponsored by Eastern Cooperative Oncology Group.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 722 participants
- Enrollment target
- 20
- Study locations
Study Summary
RATIONALE: Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies, such as bevacizumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or deliver cancer-killing substances to them. It is not yet known whether paclitaxel works better with or without bevacizumab in treating breast cancer. PURPOSE: This randomized phase III trial is to see if paclitaxel works better with or without bevacizumab in treating patients who have locally recurrent or metastatic breast cancer.
Conditions Studied
Interventions
- DRUG Paclitaxel
- DRUG bevacizumab
Study Locations (20)
Minnesota
- CCOP - Duluth - Duluth
- Mayo Clinic Cancer Center - Rochester
- CentraCare Health Plaza - Saint Cloud
- CCOP - Metro-Minnesota - Saint Louis Park
Iowa
- CCOP - Cedar Rapids Oncology Project - Cedar Rapids
- CCOP - Iowa Oncology Research Association - Des Moines
- Siouxland Hematology-Oncology - Sioux City
North Dakota
- Medcenter One Health System - Bismarck
- CCOP - Merit Care Hospital - Fargo
- Altru Cancer Center - Grand Forks
Illinois
- CCOP - Illinois Oncology Research Association - Peoria
- CCOP - Carle Cancer Center - Urbana
Alabama
- MBCCOP - Gulf Coast - Mobile
Arizona
- CCOP - Mayo Clinic Scottsdale Oncology Program - Scottsdale
Florida
- Mayo Clinic - Jacksonville - Jacksonville
Georgia
- CCOP - Atlanta Regional - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 722 participants |
| Start Date | 2002-01-29 |
| Est. Completion | 2009-05 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00028990
The ClinicalTrials.gov registry entry for NCT00028990 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 722 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (74% lower). The listed sponsor is Eastern Cooperative Oncology Group, which has 141 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Paclitaxel is the first listed.
NCT00028990 reports 20 study locations spanning 12 distinct geographic areas - top geographies include Minnesota, Iowa, North Dakota.
Frequently Asked Questions
What is clinical trial NCT00028990 about?
NCT00028990 is a clinical study titled "Paclitaxel With or Without Bevacizumab in Treating Patients With Locally Recurrent or Metastatic Breast Cancer". RATIONALE: Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies, such as bevacizumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others fi...
What is the current status of trial NCT00028990?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 722 participants. The study started on 2002-01-29. Estimated completion is 2009-05.
What conditions does trial NCT00028990 study?
This clinical trial studies the following conditions: Breast Cancer.
What interventions are being tested in trial NCT00028990?
The interventions under investigation include: Paclitaxel (DRUG), bevacizumab (DRUG).
Who is sponsoring clinical trial NCT00028990?
This trial is sponsored by Eastern Cooperative Oncology Group, which has 141 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00028990 being conducted?
This trial has 20 study locations across Alabama, Arizona, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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