Yale University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Yale University sits in the top decile of US sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count).

1,492 total trials 254 currently recruiting 1005 completed early-phase tilt top decile by trial count

Yale University: 1,492 sponsored US clinical trials, 254 recruiting.

Yale University sponsors 1,492 registered US clinical trials on ClinicalTrials.gov, 254 of them currently recruiting, and 1,005 completed. 99 of these trials are in Phase 3-4 (later-stage) and 579 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Opioid Use Disorder, with 19 trials.

Top-decile sponsor footprint

Yale University ranks in the top decile of sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

1,005 of 1,138 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,492 total, page 5 of 30

RECRUITING NA

Song-making In a Group (SING)

NCT05929352

RECRUITING NA

Alcohol-ROC-Training

NCT05491551

RECRUITING NA

Promoting Alcohol Treatment Engagement Post-hospitalization

NCT05338151

RECRUITING Early Phase 1

IV Pulsed-Nicotine as a Model of Smoking: The Effects of Dose and Delivery Rate

NCT05176418

RECRUITING Phase 2

Yale Steroid Enhanced Versus Exparel Nerveblock TKA RCT Study

NCT05279092

RECRUITING

Intestinal Immunity in Neurologic Disease

NCT06329453

RECRUITING NA

Culturally Responsive Community Driven Substance Use Recovery for Black and Latinx Population

NCT05260047

RECRUITING Phase 1

SV2A in Older Adults

NCT05465538

RECRUITING NA

Use of Psychologist-administered Cognitive Behavioral Therapy (CBT) or Self-administered CBT for the Treatment of Anxiety and/or Depression in Inflammatory Bowel Disease (IBD)

NCT05377840

RECRUITING Early Phase 1

Cardiovascular Disease Risk in Women With Endometriosis

NCT03746535

RECRUITING

Identifying and Characterizing Preclinical MS

NCT05787795

RECRUITING Phase 1

Mechanisms of Diuretic Resistance in Heart Failure, Aim 1

NCT05323487

RECRUITING Early Phase 1

Functional Neuroimaging of Alcoholism Vulnerability: Probing Glutamate and Reward, Using the mGluR5 Inhibitor Mavoglurant

NCT05203965

RECRUITING Phase 2

Catheter-Related Early Thromboprophylaxis With Enoxaparin Studies

NCT04924322

RECRUITING Early Phase 1

SV2A Density Cannabis Use Disorder

NCT05472818

RECRUITING NA

Transcranial Magnetic Stimulation (TMS) Study for Adults With Autism Spectrum Disorder (ASD)

NCT04936009

RECRUITING Phase 1

Novel Combination of Belantamab Mafodotin and Elotuzumab to Enhance Therapeutic Efficacy in Multiple Myeloma

NCT05002816

RECRUITING Phase 2

Pharmacological and Behavioral Treatment After Bariatric Surgery

NCT05157698

RECRUITING Early Phase 1

Cannabidiol in Opioid Use Disorder and Chronic Pain

NCT04587791

RECRUITING

CRUSH PAD: Real-world Outcomes Following Use of Shockwave Intravascular Lithotripsy (IVL) Technology in Calcified Common Femoral Lesions

NCT05145478

RECRUITING Phase 4

The Stimulation To Induce Mothers Study

NCT05079841

RECRUITING NA

Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With PrEP Adherence and Support Services

NCT04738825

RECRUITING

Genomic Predictors of Recurrent Pregnancy Loss

NCT05444283

RECRUITING

Aberrant Synaptic Plasticity in Cocaine Use Disorder: A 11C-UCB-J PET Study

NCT04721418

RECRUITING Early Phase 1

Toward a Computationally-Informed, Personalized Treatment for Hallucinations

NCT04366518

RECRUITING

Congenital Uterine Anomalies: Identifying Cancer Associations and Genetic and Environmental Factors to Improve Clinical Care

NCT04661072

RECRUITING Phase 2

Prazosin for Alcohol Use Disorder With Withdrawal Symptoms

NCT04793685

RECRUITING Phase 2

Pharmacological and Behavioral Treatment After Bariatric Surgery: Acute (Stage 1)

NCT04599478

RECRUITING

Pathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)

NCT04634643

RECRUITING Early Phase 1

CBD-Microglia PET Study

NCT04398719

RECRUITING Phase 2

Regulating Blood Pressure During Recovery From Intracerebral Hemorrhage and Ischemic Stroke

NCT04760717

RECRUITING Phase 2

Ertugliflozin in Chronic Heart Failure

NCT04438213

RECRUITING NA

Stress and Congestive Heart Failure

NCT04551560

RECRUITING Phase 1

Dose-Deescalated 3-Fraction Stereotactic Body Radiotherapy For Centrally Located Lung Cancer

NCT04210492

RECRUITING Phase 2

Mechanistic Evaluation of Guanfacine on Drinking Behavior in Women and Men With Alcohol Use Disorders

NCT03764098

RECRUITING

Rheumatology Patient Registry and Biorepository

NCT04402086

RECRUITING NA

Operative Versus Non-Operative Management for Appendicitis With Abscess or Phlegmon

NCT04168866

RECRUITING Phase 3

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

NCT03907046

RECRUITING Phase 1

Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD

NCT04131829

RECRUITING Phase 1

Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study II

NCT04704271

RECRUITING

Real-Time Monitoring of Heart Failure Across the Yale New Haven Health System

NCT04237701

RECRUITING NA

The Recovery in Stroke Using PAP Study

NCT04130503

RECRUITING Early Phase 1

Effects of Dronabinol in Opioid Maintained Patients

NCT04025359

RECRUITING Early Phase 1

The Impact of Phosphate Metabolism on Healthy Aging

NCT03771105

RECRUITING

Natural History of Wilson Disease

NCT03334292

RECRUITING

SV2 PET Imaging With [11C]APP311

NCT03995121

RECRUITING

Hemodynamics Monitoring During Lower Body Negative Pressure (LBNP) Induced Controlled Hypovolemia

NCT03592290

RECRUITING Phase 1

Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study I

NCT02811510

RECRUITING NA

Imaging SV2A in Mood Disorders

NCT02734602

RECRUITING

The EXPLORE MG Registry for Myasthenia Gravis

NCT03792659

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Phase Distribution

PhaseTrial count
Phase 1 312
Phase 2 267
Phase 3 52
Phase 4 47

What is open in the Yale University pipeline

254 recruiting of 1,492 indexed (17% open); 1,005 completed (67%).

Phase mix: 99 late (III/IV) vs 579 early (I/II) (early-phase heavy).

Top condition: Opioid Use Disorder (19 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Yale University: open-pipeline peers nationwide

Peers matched on 1,492 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Yale UniversityWashington University School of MedicineJohns Hopkins UniversityUniversity of PennsylvaniaNovartis PharmaceuticalsNYU Langone HealthCSL BehringPenn State UniversityUniversity of Hawaii
Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,492 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Yale University page

1,492 registered trials is a research-attention snapshot, not an endorsement of Yale University or any single study.

  • 254 of Yale University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Opioid Use Disorder is the condition Yale University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Opioid Use Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Yale University pipeline card: 1,492 registered trials from official public datasets.Report a data error.