Yale University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Yale University sits in the top decile of US sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count).

1,492 total trials 254 currently recruiting 1005 completed early-phase tilt top decile by trial count

Yale University: 1,492 sponsored US clinical trials, 254 recruiting.

Yale University sponsors 1,492 registered US clinical trials on ClinicalTrials.gov, 254 of them currently recruiting, and 1,005 completed. 99 of these trials are in Phase 3-4 (later-stage) and 579 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Opioid Use Disorder, with 19 trials.

Top-decile sponsor footprint

Yale University ranks in the top decile of sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

1,005 of 1,138 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,492 total, page 6 of 30

RECRUITING Phase 2

A Phase II Evaluation of Afatinib in Patients With Persistent or Recurrent HER2-positive Uterine Serous Carcinoma

NCT02491099

RECRUITING Phase 1

Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans

NCT02781519

RECRUITING

Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

NCT01730781

RECRUITING NA

Reversal of Lipid-Induced Insulin Resistance

NCT02193295

ACTIVE NOT RECRUITING NA

Breast Cancer Screening Decision Aid

NCT07515846

ACTIVE NOT RECRUITING NA

A Trial to Reduce Inappropriate Prescribing to Older Adults Visiting the Emergency Department

NCT07146763

ACTIVE NOT RECRUITING Phase 1

BHV-7000 Responsive Neurostimulation System (RNS) Study

NCT07125261

ACTIVE NOT RECRUITING NA

Impact of a Community Health Worker Strategy on Produce Prescription Program Uptake Among People With Diabetes

NCT06401668

ACTIVE NOT RECRUITING Phase 2

Effects of Interleukin (IL)-17A Inhibition on Idiopathic Subglottic Stenosis

NCT05309616

ACTIVE NOT RECRUITING

An Observational Study Using Artificial Intelligence (AI) Algorithms on Electrocardiography (ECG), Point-of-care Ultrasound (POCUS), and Transthoracic Echocardiophy (TTE) to Estimate the Under-diagnosis of Transthyretin Amyloid Cardiomyopathy (ATTR-CM) Across a Diverse Range of US Health Systems.

NCT07062848

ACTIVE NOT RECRUITING NA

Community Health Equity Accelerator (CHEA) Pediatric Asthma Intervention

NCT06507943

ACTIVE NOT RECRUITING NA

Targeting Fronto-Striatal Neural Circuitry Using Repetitive Transcranial Magnetic Stimulation to Reduce Irritability

NCT07678060

ACTIVE NOT RECRUITING Phase 2

Pharmacist-led Intervention for Injectable HIV Treatment for Women With Health-related Social Needs

NCT06411223

ACTIVE NOT RECRUITING Phase 2

Sodium-Glucose Cotransporter-2 Inhibitor for Acute Cardiorenal Syndrome: A Feasibility Study

NCT06111768

ACTIVE NOT RECRUITING Phase 1

Apremilast for Alcohol Use Disorder Treatment in Women and Men

NCT06324435

ACTIVE NOT RECRUITING NA

Impact of Family-Centered Care for Intimate Partner Violence (IPV)

NCT06071299

ACTIVE NOT RECRUITING Phase 2

A Study of Sacituzumab Govitecan (IMMU-132) in Platinum-resistant Ovarian Cancer Patients

NCT06028932

ACTIVE NOT RECRUITING Phase 1

Oral Dronabinol-HIV

NCT06034314

ACTIVE NOT RECRUITING Phase 1

Utility of Brexanolone to Target Stress-induced Alcohol Use Among Men and Women With Posttraumatic Stress Disorder

NCT05223829

ACTIVE NOT RECRUITING Phase 1

Effects of Repeated Psilocybin Dosing in OCD

NCT05370911

ACTIVE NOT RECRUITING NA

Pain Care at Home to Amplify Function (Pain CHAMP)

NCT05333341

ACTIVE NOT RECRUITING NA

Buprenorphine Integration Research and Community Health

NCT05668780

ACTIVE NOT RECRUITING Phase 3

FRIEND: Fibroids and Unexplained Infertility Treatment With Epigallocatechin Gallate; A Natural CompounD in Green Tea

NCT05364008

ACTIVE NOT RECRUITING NA

Potential Impact of Menthol Ban in Cigarettes and E-cigarettes

NCT05259566

ACTIVE NOT RECRUITING NA

Dissemination and Implementation of the Bright Bodies Intervention for Childhood Obesity

NCT05595161

ACTIVE NOT RECRUITING

The DISCOVER INOCA Prospective Multi-center Registry

NCT05288361

ACTIVE NOT RECRUITING NA

Addressing Risk Through Community Treatment for Infectious Disease and Opioid Use Disorder Now (ACTION) Among Justice-involved Populations

NCT05286879

ACTIVE NOT RECRUITING Phase 2

Pharmacological and Behavioral Treatments After Bariatric Surgery: Maintenance Treatment (Stage 2a)

NCT04605081

ACTIVE NOT RECRUITING Phase 2

Pharmacological and Behavioral Treatment After Bariatric Surgery: Medication Change for Non-Responders (Stage 2b)

NCT04599504

ACTIVE NOT RECRUITING

Novel physIologiC prEdictors of Positive Airway Pressure Effectiveness

NCT05067088

ACTIVE NOT RECRUITING

SCOPE-CLI: Shifting Care and Outcomes for Patients With Endangered Limbs

NCT04710563

ACTIVE NOT RECRUITING

Neuro-immune Interactome in Parkinson's Disease

NCT07026929

ACTIVE NOT RECRUITING NA

Transitions Clinic Network: Post Incarceration Addiction Treatment, Healthcare, and Social Support

NCT04309565

ACTIVE NOT RECRUITING Early Phase 1

AB154 Combined With AB122 for Recurrent Glioblastoma

NCT04656535

ACTIVE NOT RECRUITING Phase 1

Fixed Order, Open-Label, Dose-Escalation Study of DMT in Humans

NCT04711915

ACTIVE NOT RECRUITING

Evaluating the Immune Response to COVID19 Vaccination in Immunodeficient Patients

NCT05286242

ACTIVE NOT RECRUITING Phase 2

The Study of NC318 Alone or in Combination With Pembrolizumab in Patients With Advanced Non-small Cell Lung Cancer

NCT04699123

ACTIVE NOT RECRUITING

Exploring Outcomes and Characteristics of Myasthenia Gravis 2

NCT06002945

ACTIVE NOT RECRUITING NA

Behavior Therapy for Irritability in Autism

NCT04654260

ACTIVE NOT RECRUITING NA

A Trial to Determine Weight Gain Benefits of Caloric Supplementation for NAS Infants

NCT04419857

ACTIVE NOT RECRUITING Phase 1

A Study of APX005M in Combination With Nivolumab and Ipilimumab in Treatment Naïve Patients With Advanced Melanoma or Renal Cell Carcinoma (RCC)

NCT04495257

ACTIVE NOT RECRUITING NA

Physician-Modified Fenestrated and Branched Aortic Endografting for TAAA

NCT02989948

ACTIVE NOT RECRUITING Phase 2

A Study of Sacituzumab Govitecan (IMMU-132) in Endometrial Carcinoma

NCT04251416

ACTIVE NOT RECRUITING Phase 2

Phase II Study to Evaluate Modified Folfirinox and Stereotactic Body Radiation Therapy in Non-metastatic Unresectable Pancreatic Adenocarcinoma

NCT03991962

ACTIVE NOT RECRUITING NA

Transcranial Magnetic Stimulation on Neural and Behavioral Facets of Social Cognition in Autism Spectrum Disorder

NCT04242355

ACTIVE NOT RECRUITING Phase 2

Ipilimumab and Nivolumab in Recurrent Extensive Stage Small Cell Lung Cancer After Receiving Platinum-based Chemotherapy

NCT03670056

ACTIVE NOT RECRUITING Phase 2

Does Propranolol, a Beta Blocker, Attenuate Stress-Induced Drinking?

NCT03588754

ACTIVE NOT RECRUITING NA

CB1R in Synthetic Psychoactive Cannabinoids

NCT03539575

ACTIVE NOT RECRUITING Phase 2

Therapeutic Effect of Cytoreductive Radical Prostatectomy in Men With Newly Diagnosed Metastatic Prostate Cancer

NCT03456843

ACTIVE NOT RECRUITING Phase 1

Psilocybin - Induced Neuroplasticity in the Treatment of Major Depressive Disorder

NCT03554174

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Phase Distribution

PhaseTrial count
Phase 1 312
Phase 2 267
Phase 3 52
Phase 4 47

What is open in the Yale University pipeline

254 recruiting of 1,492 indexed (17% open); 1,005 completed (67%).

Phase mix: 99 late (III/IV) vs 579 early (I/II) (early-phase heavy).

Top condition: Opioid Use Disorder (19 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Yale University: open-pipeline peers nationwide

Peers matched on 1,492 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Yale UniversityWashington University School of MedicineJohns Hopkins UniversityUniversity of PennsylvaniaNovartis PharmaceuticalsNYU Langone HealthCSL BehringPenn State UniversityUniversity of Hawaii
Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,492 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Yale University page

1,492 registered trials is a research-attention snapshot, not an endorsement of Yale University or any single study.

  • 254 of Yale University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Opioid Use Disorder is the condition Yale University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Opioid Use Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Yale University pipeline card: 1,492 registered trials from official public datasets.Report a data error.