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NCT05157698 · ClinicalTrials.gov registry record · Phase 2

Pharmacological and Behavioral Treatment After Bariatric Surgery

A Phase 2 study of Obesity, sponsored by Yale University.

Recruiting
Registry status
Phase 2
Development phase
160
Enrollment target
1
Study location

NCT05157698: Recruiting Phase 2 study of Obesity, sponsored by Yale University.

NCT05157698 is a Phase 2 study of Obesity that is actively recruiting participants, run by Yale University. The registered enrollment target is 160 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05157698, a Phase 2 study of Obesity, is actively recruiting participants, sponsored by Yale University.

RECRUITING
Registry status
Phase 2
Development phase
160 participants
Enrollment target
1
Study location

Study Summary

This study will compare the effectiveness of behavioral and pharmacologic treatment, alone and combined, for improvements in weight loss, cardiovascular risk factors, and psychosocial functioning following metabolic and bariatric surgery.

Primary Outcome

BMI is calculated using measured height and weight

Conditions Studied

Interventions

  • OTHER Placebo
  • BEHAVIORAL Behavioral Weight Loss
  • DRUG Naltrexone and Bupropion Combination

Study Locations (1)

Connecticut

  • Yale School of Medicine - New Haven

Trial Details

FieldValue
Enrollment Target 160 participants
Start Date 2022-01-13
Est. Completion 2028-01-12
Phase Phase 2
Yale University

1,492 total trials

What NCT05157698 shows while recruiting

NCT05157698 is an interventional study that assigns participants to a tested intervention. The registered 160 participants enrollment target is mid-sized for trials with a published cap, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (80% lower).

The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT05157698 reports a single indexed study location in Connecticut.

Frequently Asked Questions

What is clinical trial NCT05157698 about?

NCT05157698 is a clinical study titled "Pharmacological and Behavioral Treatment After Bariatric Surgery". This study will compare the effectiveness of behavioral and pharmacologic treatment, alone and combined, for improvements in weight loss, cardiovascular risk factors, and psychosocial functioning following metabolic and bariatric surgery.

What is the current status of trial NCT05157698?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 160 participants. The study started on 2022-01-13. Estimated completion is 2028-01-12.

What conditions does trial NCT05157698 study?

This clinical trial studies the following conditions: Obesity.

What interventions are being tested in trial NCT05157698?

The interventions under investigation include: Placebo (OTHER), Behavioral Weight Loss (BEHAVIORAL), Naltrexone and Bupropion Combination (DRUG).

Who is sponsoring clinical trial NCT05157698?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05157698 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Obesity

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05157698's enrollment target sits among peer trials

160 359th of 1053 higher than 691 of 1,053 other Obesity trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05157698, the US trial registry maintained by the National Library of Medicine. NCT05157698 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.