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NCT04738825 · ClinicalTrials.gov registry record · NA
Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With PrEP Adherence and Support Services
A NA study of Opioid Use Disorder and HIV Prevention Program, sponsored by Yale University.
- Recruiting
- Registry status
- NA
- Development phase
- 526
- Enrollment target
- 6
- Study locations
NCT04738825: Recruiting NA study of Opioid Use Disorder and HIV Prevention Program, sponsored by Yale University.
NCT04738825 is a NA study of Opioid Use Disorder and HIV Prevention Program that is actively recruiting participants, run by Yale University. The registered enrollment target is 526 participants, below the 4,654-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (89% lower). The trial reports 6 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04738825, a NA study of Opioid Use Disorder and HIV Prevention Program, is actively recruiting participants, sponsored by Yale University.
- RECRUITING
- Registry status
- NA
- Development phase
- 526 participants
- Enrollment target
- 6
- Study locations
Study Summary
The proposed study will be a 24-week intervention with a 12-month follow-up period to evaluate the impact of contingency management with stepped care to pre-exposure prophylaxis (PrEP) adherence and support services (CoMPASS) to promote HIV prevention among individuals with opioid use disorder who have injected drugs in their lifetime. In parallel, the investigators will conduct an implementation focused process evaluation to inform real-world implementation of CoMPASS. .
Primary Outcome
Determined by tenofovir-diphosphate levels by dried blood spot testing or objective confirmation.
Conditions Studied
Interventions
- BEHAVIORAL Contingency Management with stepped care to PrEP adherence and support services (CoMPASS)
Study Locations (6)
Connecticut
- Recovery Network of Programs, Inc - Bridgeport
- Liberations Program, Inc - Bridgeport
- Apex Community Care. Inc. - Danbury
- Greater Hartford Harm Reduction Coalition- SWAN - New Haven
- APT - New Haven
Massachusetts
- Stanley Street Treatment and Resource Center - Fall River
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 526 participants |
| Start Date | 2021-10-04 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
What NCT04738825 shows while recruiting
NCT04738825 is an interventional study that assigns participants to a tested intervention. The registered 526 participants enrollment target is mid-sized for trials with a published cap, below the 4,654-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (89% lower).
The record links to 2 conditions, with Opioid Use Disorder appearing as the primary indexed condition, and to 1 intervention - of which Contingency Management with stepped care to PrEP adherence and support services (CoMPASS) is the first listed.
NCT04738825 lists 6 locations in 2 states (Connecticut, Massachusetts).
Frequently Asked Questions
What is clinical trial NCT04738825 about?
NCT04738825 is a clinical study titled "Promoting HIV Risk Reduction Among People Who Inject Drugs: A Stepped Care Approach Using Contingency Management With PrEP Adherence and Support Services". The proposed study will be a 24-week intervention with a 12-month follow-up period to evaluate the impact of contingency management with stepped care to pre-exposure prophylaxis (PrEP) adherence and support services (CoMPASS) to promote HIV prevention among individuals with opioid use disorder who h...
What is the current status of trial NCT04738825?
This trial is currently recruiting. It is a NA study. The enrollment target is 526 participants. The study started on 2021-10-04. Estimated completion is 2026-06-30.
What conditions does trial NCT04738825 study?
This clinical trial studies the following conditions: Opioid Use Disorder, HIV Prevention Program.
What interventions are being tested in trial NCT04738825?
The interventions under investigation include: Contingency Management with stepped care to PrEP adherence and support services (CoMPASS) (BEHAVIORAL).
Who is sponsoring clinical trial NCT04738825?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04738825 being conducted?
This trial has 6 study locations across Connecticut, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04738825's enrollment target sits among peer trials
526 34th of 257 higher than 224 of 257 other Opioid Use Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Opioid Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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