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NCT03771105 · ClinicalTrials.gov registry record · Early Phase 1

The Impact of Phosphate Metabolism on Healthy Aging

A Early Phase 1 study, sponsored by Yale University.

Recruiting
Registry status
Early Phase 1
Development phase
30
Enrollment target

NCT03771105: Recruiting Early Phase 1 study, sponsored by Yale University.

NCT03771105 is a Early Phase 1 study that is actively recruiting participants, run by Yale University. The registered enrollment target is 30 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (43% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03771105, a Early Phase 1 study, is actively recruiting participants, sponsored by Yale University.

RECRUITING
Registry status
Early Phase 1
Development phase
30 participants
Enrollment target

Study Summary

Determine the association between duration and dose of chronic conventional therapy with Pi and renal (nephrocalcinosis/nephrolithiasis), vascular (endothelial function), and cardiovascular function (echo- cardiography) in patients with hereditary hypophosphatemic rickets with hypercalciuria (HHRH) and patients with X-linked hypophosphatemia (XLH).

Primary Outcome

PTH levels are expected to increase over baseline after phosphate supplement (Pi).

Interventions

  • DRUG phosphate

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2019-01-01
Est. Completion 2028-04
Phase Early Phase 1
Yale University

1,492 total trials

What NCT03771105 shows while recruiting

NCT03771105 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (43% lower).

The record links to 0 conditions, and to 1 intervention - of which phosphate is the first listed.

NCT03771105 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03771105 about?

NCT03771105 is a clinical study titled "The Impact of Phosphate Metabolism on Healthy Aging". Determine the association between duration and dose of chronic conventional therapy with Pi and renal (nephrocalcinosis/nephrolithiasis), vascular (endothelial function), and cardiovascular function (echo- cardiography) in patients with hereditary hypophosphatemic rickets with hypercalciuria (HHRH) ...

What is the current status of trial NCT03771105?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 30 participants. The study started on 2019-01-01. Estimated completion is 2028-04.

What interventions are being tested in trial NCT03771105?

The interventions under investigation include: phosphate (DRUG).

Who is sponsoring clinical trial NCT03771105?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03771105's enrollment target sits among peer trials

30 807th of 2000 higher than 1,075 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03771105, the US trial registry maintained by the National Library of Medicine. NCT03771105 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.