VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 10 of 34

NOT YET RECRUITING NA

CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)

NCT05996328
NOT YET RECRUITING NA

Pain and Smoking Study - Interactive Voice Response

NCT06442514
NOT YET RECRUITING NA

Development of a Power Training Program to Improve Mobility in Older Veterans

NCT07210645
NOT YET RECRUITING NA

Pro-social Power Training Activity for Aging and Well-being With Chronic Kidney Disease

NCT06089057
NOT YET RECRUITING NA

Optimization of Adaptive Rowing Seating

NCT07099625
NOT YET RECRUITING NA

Accelerated and Extended-iTBS Targeting Inhibitory Control in Veterans With ADHD

NCT07442058
NOT YET RECRUITING NA

Employing Peer Outreach and Whole Health in Recovery for Homeless-Experienced Veterans

NCT07309224
NOT YET RECRUITING Phase 3

Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial to Evaluate the Efficacy and Safety of a GLP-1 Receptor Agonist Semaglutide in U.S. Veterans With Alcohol Use Disorder

NCT07218354
NOT YET RECRUITING Phase 1

Phase I Trial of pH Resections of GBM at VA

NCT07218367
NOT YET RECRUITING NA

Tele-Exercise for MERP

NCT07018466
NOT YET RECRUITING NA

Evaluating the Efficacy of a Vocational Counseling Intervention to Improve Occupational Functioning and Employment Quality Among Veterans With Mental Health and Substance Use Disorders

NCT07097376
NOT YET RECRUITING NA

Preventing Early-Onset Colorectal Cancer in the VA

NCT07071454
NOT YET RECRUITING Phase 3

Personalized vs Standard of Care Treatment for Helicobacter Pylori Eradication Among Veterans

NCT07104318
NOT YET RECRUITING NA

SleepSMART for Veterans With Insomnia and Mild Cognitive Impairment

NCT07397182
NOT YET RECRUITING NA

A Randomized Controlled Trial of a Web-Based Moral Elevation Intervention for Veterans With PTSD

NCT06788678
NOT YET RECRUITING Phase 1

Reducing Firearm Suicide Among Veterans: Evaluating the Effectiveness of Peer-Delivered Lethal Means Counseling

NCT07033884
NOT YET RECRUITING NA

rTMS for Tobacco Use in Veterans

NCT07050862
NOT YET RECRUITING NA

Boosting Exercise Adherence in Knee Osteoarthritis

NCT07219732
NOT YET RECRUITING NA

Durability of Yoga for Veterans With Low Back Pain

NCT07053787
NOT YET RECRUITING NA

Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans

NCT06627569
NOT YET RECRUITING NA

Testing an Adaptive Intervention for Peer-Supported Mobile Health for Primary Care Veterans With Psychological Distress

NCT07507747
NOT YET RECRUITING Phase 3

Rapid Acceleration Process for Intensive Treatment of PTSD in 5 Days

NCT07167940
NOT YET RECRUITING Phase 3

Veterans' Intervention Blending NeuRomodulation and YogA for Chronic Low BackPaiN Treatment: VIBRANT

NCT07158567
NOT YET RECRUITING Phase 3

Testing the Use of VA Peer Specialists to Prevent Veteran Suicide

NCT07286383
NOT YET RECRUITING NA

Empowerment Program to Reduce Treatment of Asymptomatic Bacteriuria in Veterans With Spinal Cord Injury

NCT07430904
NOT YET RECRUITING NA

Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation: Effect on Imaging and Serum Biomarkers of Skeletal Muscle Mass and Bone Strength.

NCT07418398
NOT YET RECRUITING NA

Influence Of A Slope Adaptive Foot On Participation Of Veterans With Lower-Limb Amputations

NCT07266077
NOT YET RECRUITING NA

Enhancing Veteran-Clinical Collaboration in VA PRRCs

NCT06898879
NOT YET RECRUITING Phase 4

Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson Disease

NCT07187466
NOT YET RECRUITING NA

Development and Feasibility of CTraC-FIT

NCT07132944
NOT YET RECRUITING NA

Effect of a Microprocessor-controlled Prosthetic Knee Joint on K2 Level Ambulators

NCT07103798
NOT YET RECRUITING NA

iBCI Optimization for Veterans With Paralysis

NCT05470478
NOT YET RECRUITING NA

Adjustable Prosthetic Sockets

NCT07397169
NOT YET RECRUITING Phase 1

Pilot and Feasibility Study of Intra-articular Anti-CD14 for the Treatment of Knee Osteoarthritis

NCT07481474
NOT YET RECRUITING Phase 4

The Effects of Orexin Antagonism on Fear Extinction in PTSD

NCT06788522
NOT YET RECRUITING NA

Repetitive Transcranial Magnetic Stimulation Treatment of Stimulant Use Disorder

NCT07112105
NOT YET RECRUITING NA

PEP Buddy in Pulmonary Rehabilitation

NCT07404826
NOT YET RECRUITING NA

Spinal Neurorehabilitation for Veterans With SCI

NCT07222046
COMPLETED

Understanding Perceived Access and Receipt of Gender-affirming Treatments Among Transgender Veterans

NCT06615401
COMPLETED NA

Safety Aid Reduction Treatment for PTSD Among Veterans

NCT04515784
TERMINATED NA

Home-based Conservative Care Model for Advanced Kidney Disease

NCT06411613
COMPLETED NA

Relational Playbook Pilot Study

NCT06456021
COMPLETED NA

Intervention to Reduce Safety Behaviors

NCT05996419
COMPLETED NA

Home Safety Intervention

NCT06216327
COMPLETED NA

Adapting Treatment Delivery to Improve Retention in Evidence-Based PTSD Treatment

NCT06335589
COMPLETED NA

Impact of VVV Group for Veterans With SMI

NCT05562674
COMPLETED NA

LASER Pilot Project

NCT05966636
COMPLETED NA

VOICES Socials for Older Veterans With Depression

NCT06145334
COMPLETED NA

A Novel Cooling Vest to Protect Persons With SCI From Hyperthermia

NCT05441449
COMPLETED NA

Pilot Testing a Virtual Mindfulness-Based Intervention to Improve Veterans' Health

NCT05975008
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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

Therapeutic Areas

PTSD 28
Depression 28
Stroke 27
Posttraumatic Stress Disorder 26
Post Traumatic Stress Disorder 19
Stress Disorders, Post-Traumatic 17
Parkinson's Disease 16
Chronic Pain 16
Spinal Cord Injury 15
Obesity 14

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Related

Compare saved trials side-by-side

Read our methodology - how this data is sourced, computed, and verified.
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.