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NCT07696988 · ClinicalTrials.gov registry record · NA
PNS to Improve Vascular Function and Limb Health in Veterans
A NA study, sponsored by VA Office of Research and Development.
- Not yet
- Registry status
- NA
- Development phase
- 42
- Enrollment target
NCT07696988: Clinical Trial NA study, sponsored by VA Office of Research and Development.
NCT07696988 is a NA study that has not yet begun recruiting, run by VA Office of Research and Development. The registered enrollment target is 42 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07696988, a NA study, has not yet begun recruiting, sponsored by VA Office of Research and Development.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 42 participants
- Enrollment target
Study Summary
Establishing a sensitive, scalable physiological test for neurovascular reflex integrity and investigating whether targeted peripheral neural stimulation can enhance perfusion and vasodilatory responsiveness.
Primary Outcome
Autonomic reflex testing including thermal axon reflex and pressure induced vasoconstriction will be applied. The cutaneous blood flow in the lower limb will be measured using laser doppler flowmetry. The flux is divided by mean arterial pressure to calculate cutaneous vascular conductance. This provides a physiologically relevant metric of microvascular control by accounting for systemic pressure fluctuations
Interventions
- DEVICE Chronically Implanted Neural and Muscular Interface
- DEVICE Peripheral Nerve Stimulation (PNS)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2026-11-02 |
| Est. Completion | 2030-05-30 |
| Phase | NA |
What is known before NCT07696988 opens enrollment
NCT07696988 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Chronically Implanted Neural and Muscular Interface is the first listed.
NCT07696988 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07696988 about?
NCT07696988 is a clinical study titled "PNS to Improve Vascular Function and Limb Health in Veterans". Establishing a sensitive, scalable physiological test for neurovascular reflex integrity and investigating whether targeted peripheral neural stimulation can enhance perfusion and vasodilatory responsiveness.
What is the current status of trial NCT07696988?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 42 participants. The study started on 2026-11-02. Estimated completion is 2030-05-30.
What interventions are being tested in trial NCT07696988?
The interventions under investigation include: Chronically Implanted Neural and Muscular Interface (DEVICE), Peripheral Nerve Stimulation (PNS) (DEVICE).
Who is sponsoring clinical trial NCT07696988?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07696988's enrollment target sits among peer trials
42 1436th of 2000 higher than 555 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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