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NCT07210606 · ClinicalTrials.gov registry record · Phase 4
Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment
A Phase 4 study, sponsored by VA Office of Research and Development.
- Not yet
- Registry status
- Phase 4
- Development phase
- 200
- Enrollment target
NCT07210606: Clinical Trial Phase 4 study, sponsored by VA Office of Research and Development.
NCT07210606 is a Phase 4 study that has not yet begun recruiting, run by VA Office of Research and Development. The registered enrollment target is 200 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07210606, a Phase 4 study, has not yet begun recruiting, sponsored by VA Office of Research and Development.
- NOT YET RECRUITING
- Registry status
- Phase 4
- Development phase
- 200 participants
- Enrollment target
Study Summary
Central sleep apnea (CSA) is common in patients with heart failure and those using opioid analgesics. Unfortunately, effective treatment of central apnea remains elusive, pressure therapy given the modest efficiency of positive airway pressure therapy. The focus of this proposal is to identify mechanistic pathways to guide future therapeutic interventions for central sleep apnea based on the strong premise that multi-modality therapy will normalize respiration and hence mitigate adverse long-term consequences of CSA. The investigators' proposed studies will test combination therapies, including positive airway pressure (PAP) plus a pharmacological agent who have heart failure or are using opioid analgesics. The investigators anticipate that findings will inform future clinical trials to improve care and quality of life among Veterans suffering from central sleep apnea, which remains difficult to treat using existing approaches.
Interventions
- DRUG Trazodone + PAP therapy
- DRUG Oxygen + PAP therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2026-10-01 |
| Est. Completion | 2030-12-31 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07210606
The ClinicalTrials.gov registry entry for NCT07210606 describes a study currently listed as not yet recruiting, categorized as Phase 4. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Trazodone + PAP therapy is the first listed.
NCT07210606 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07210606 about?
NCT07210606 is a clinical study titled "Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment". Central sleep apnea (CSA) is common in patients with heart failure and those using opioid analgesics. Unfortunately, effective treatment of central apnea remains elusive, pressure therapy given the modest efficiency of positive airway pressure therapy. The focus of this proposal is to identify mecha...
What is the current status of trial NCT07210606?
This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 200 participants. The study started on 2026-10-01. Estimated completion is 2030-12-31.
What interventions are being tested in trial NCT07210606?
The interventions under investigation include: Trazodone + PAP therapy (DRUG), Oxygen + PAP therapy (DRUG).
Who is sponsoring clinical trial NCT07210606?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
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