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NCT00475982 · ClinicalTrials.gov registry record · NA

Effect of Weight Loss on Prostate Cancer Pathology

A NA study, sponsored by VA Office of Research and Development.

Completed
Registry status
NA
Development phase
44
Enrollment target

NCT00475982: Completed NA study, sponsored by VA Office of Research and Development.

NCT00475982 is a NA study that has completed, run by VA Office of Research and Development. The registered enrollment target is 44 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00475982, a NA study, has completed, sponsored by VA Office of Research and Development.

COMPLETED
Registry status
NA
Development phase
44 participants
Enrollment target

Study Summary

The purpose of this study is to determine if weight loss prior to radical prostatectomy effects chemical substances in the blood stream and prostate tissue that may affect prostate cancer development and progression.

Primary Outcome

The primary objective is to compare the mean apoptotic index in the radical prostatectomy malignant epithelium between the Weight Loss Group and the Control Group-No Weight Loss. The apoptotic index will be measured in the malignant epithelium with the highest Gleason grade. TUNEL staining was used to identify these apoptotic cells and measure the apoptotic index, which is the percent of cells stained from the sample.

Interventions

  • BEHAVIORAL Weight Loss
  • OTHER No Weight Loss Group

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2009-01
Est. Completion 2016-03
Phase NA
VA Office of Research and Development

1,668 total trials

What the finished NCT00475982 record still lists

NCT00475982 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 2 interventions - of which Weight Loss is the first listed.

NCT00475982 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00475982 about?

NCT00475982 is a clinical study titled "Effect of Weight Loss on Prostate Cancer Pathology". The purpose of this study is to determine if weight loss prior to radical prostatectomy effects chemical substances in the blood stream and prostate tissue that may affect prostate cancer development and progression.

What is the current status of trial NCT00475982?

This trial is currently completed. It is a NA study. The enrollment target is 44 participants. The study started on 2009-01. Estimated completion is 2016-03.

What interventions are being tested in trial NCT00475982?

The interventions under investigation include: Weight Loss (BEHAVIORAL), No Weight Loss Group (OTHER).

Who is sponsoring clinical trial NCT00475982?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00475982's enrollment target sits among peer trials

44 1423rd of 2000 higher than 566 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00475982, the US trial registry maintained by the National Library of Medicine. NCT00475982 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.