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NCT00732199 · ClinicalTrials.gov registry record · NA

Determinants of Age Related Breathing Instability During Non-Rapid-Eye-Movement (NREM) Sleep

A NA study, sponsored by VA Office of Research and Development.

Completed
Registry status
NA
Development phase
92
Enrollment target

NCT00732199: Completed NA study, sponsored by VA Office of Research and Development.

NCT00732199 is a NA study that has completed, run by VA Office of Research and Development. The registered enrollment target is 92 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00732199, a NA study, has completed, sponsored by VA Office of Research and Development.

COMPLETED
Registry status
NA
Development phase
92 participants
Enrollment target

Study Summary

The purpose for this research protocol was to examine the role of breathing control mechanisms that determine the development of sleep-disordered breathing in the elderly. This proposal focused on key factors that contribute to the control of ventilation in elderly adults during sleep. The investigators studied the age-specific changes in ventilatory control in older and young adults during NREM sleep.

Primary Outcome

The AT was defined as the end-tidal (PETCO2) that demarcated the central apnea closest to the eupneic PETCO2. The CO2 reserve was defined as the difference in PETCO2 between eupnea and AT.

Interventions

  • OTHER 1) hyperventilation via noninvasive positive pressure ventilation 2) multiple trials of episodic hypoxia

Trial Details

FieldValue
Enrollment Target 92 participants
Start Date 2008-10
Est. Completion 2015-04
Phase NA
VA Office of Research and Development

1,668 total trials

What the finished NCT00732199 record still lists

NCT00732199 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 92 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).

The record links to 0 conditions, and to 1 intervention - of which 1) hyperventilation via noninvasive positive pressure ventilation 2) multiple trials of episodic hypoxia is the first listed.

NCT00732199 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00732199 about?

NCT00732199 is a clinical study titled "Determinants of Age Related Breathing Instability During Non-Rapid-Eye-Movement (NREM) Sleep". The purpose for this research protocol was to examine the role of breathing control mechanisms that determine the development of sleep-disordered breathing in the elderly. This proposal focused on key factors that contribute to the control of ventilation in elderly adults during sleep. The investiga...

What is the current status of trial NCT00732199?

This trial is currently completed. It is a NA study. The enrollment target is 92 participants. The study started on 2008-10. Estimated completion is 2015-04.

What interventions are being tested in trial NCT00732199?

The interventions under investigation include: 1) hyperventilation via noninvasive positive pressure ventilation 2) multiple trials of episodic hypoxia (OTHER).

Who is sponsoring clinical trial NCT00732199?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00732199's enrollment target sits among peer trials

92 937th of 2000 higher than 1,062 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00732199, the US trial registry maintained by the National Library of Medicine. NCT00732199 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.