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NCT00953849 · ClinicalTrials.gov registry record · Phase 1

Vitamin D Plus Celecoxib Therapy to Stimulate Intratumoral Immune Reactivity

A Phase 1 study of Mouth Neoplasms, sponsored by VA Office of Research and Development.

Completed
Registry status
Phase 1
Development phase
21
Enrollment target
1
Study location

NCT00953849 is a Phase 1 study of Mouth Neoplasms that has completed, run by VA Office of Research and Development. The registered enrollment target is 21 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT00953849, a Phase 1 study of Mouth Neoplasms, has completed, sponsored by VA Office of Research and Development.

COMPLETED
Registry status
Phase 1
Development phase
21 participants
Enrollment target
1
Study location

Study Summary

The poor survival of Veterans with oral cancer underscores the significance of identifying new treatment approaches. The proposed studies will test a new 2 pronged immunotherapeutic approach for oral cancer patients which lessen the immune inhibitory environment while maturing cells that can stimulate T cell reactivity against oral cancer cells.

Conditions Studied

Interventions

  • DRUG Celecoxib
  • DRUG Calcitriol
  • DRUG Celecoxib plus Calcitriol

Study Locations (1)

South Carolina

  • Ralph H. Johnson VA Medical Center, Charleston, SC - Charleston

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2009-11
Est. Completion 2015-12
Phase Phase 1

Sponsor

VA Office of Research and Development

1,668 total trials

What the Registry Record Tells You About NCT00953849

The ClinicalTrials.gov registry entry for NCT00953849 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Mouth Neoplasms appearing as the primary indexed condition, and to 3 interventions - of which Celecoxib is the first listed.

NCT00953849 reports 1 study location spanning 1 distinct geographic area - top geographies include South Carolina.

Frequently Asked Questions

What is clinical trial NCT00953849 about?

NCT00953849 is a clinical study titled "Vitamin D Plus Celecoxib Therapy to Stimulate Intratumoral Immune Reactivity". The poor survival of Veterans with oral cancer underscores the significance of identifying new treatment approaches. The proposed studies will test a new 2 pronged immunotherapeutic approach for oral cancer patients which lessen the immune inhibitory environment while maturing cells that can stimula...

What is the current status of trial NCT00953849?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 2009-11. Estimated completion is 2015-12.

What conditions does trial NCT00953849 study?

This clinical trial studies the following conditions: Mouth Neoplasms.

What interventions are being tested in trial NCT00953849?

The interventions under investigation include: Celecoxib (DRUG), Calcitriol (DRUG), Celecoxib plus Calcitriol (DRUG).

Who is sponsoring clinical trial NCT00953849?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00953849 being conducted?

This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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