Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00688259 · ClinicalTrials.gov registry record · NA
Cognitive-Behavioral Therapy in Veterans With Schizophrenia
A NA study of Schizophrenia and Schizoaffective Disorder, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 122
- Enrollment target
- 1
- Study location
NCT00688259: Completed NA study of Schizophrenia and Schizoaffective Disorder, sponsored by VA Office of Research and Development.
NCT00688259 is a NA study of Schizophrenia and Schizoaffective Disorder that has completed, run by VA Office of Research and Development. The registered enrollment target is 122 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (44% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00688259, a NA study of Schizophrenia and Schizoaffective Disorder, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 122 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a study comparing the benefits of two types of individual psychotherapy (cognitive-behavioral therapy for psychosis and supportive therapy) in symptomatic Veteran outpatients diagnosed with schizophrenia or schizoaffective disorder. Treatment lasted approximately 6 months, with outcome data on symptoms, functioning, and distress levels collected at baseline, post-treatment, and 6 months post -treatment follow-up.
Primary Outcome
Mean positive symptoms Interview rating on the Brief Psychiatric Rating Scale (Ventura, Lukoff. Nuechterlein. Liberman, Green, \& Shaner, 1993), with range of 1-7 and higher scores indicating greater symptoms Ventura, J. Lukoff D, Nuechterlein KH, Liberman RP, Green M, Shaner A: Appendix 1: Brief Psychiatric Rating Scale (BPRS) Expanded Version (4.0) scales, anchor points and administration manual. International Journal of Methods in Psychiatric Research 1993; 3:227-243
Conditions Studied
Interventions
- BEHAVIORAL Supportive Therapy (ST)
- BEHAVIORAL Cognitive Behavioral Therapy for Psychosis (CBTp)
Study Locations (1)
California
- VA Greater Los Angeles Healthcare System, West Los Angeles, CA - West Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 122 participants |
| Start Date | 2009-04 |
| Est. Completion | 2015-01 |
| Phase | NA |
What the finished NCT00688259 record still lists
NCT00688259 is an interventional study that assigns participants to a tested intervention. The registered 122 participants enrollment target is mid-sized for trials with a published cap, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (44% lower).
The record links to 2 conditions, with Schizophrenia appearing as the primary indexed condition, and to 2 interventions - of which Supportive Therapy (ST) is the first listed.
NCT00688259 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT00688259 about?
NCT00688259 is a clinical study titled "Cognitive-Behavioral Therapy in Veterans With Schizophrenia". This is a study comparing the benefits of two types of individual psychotherapy (cognitive-behavioral therapy for psychosis and supportive therapy) in symptomatic Veteran outpatients diagnosed with schizophrenia or schizoaffective disorder. Treatment lasted approximately 6 months, with outcome data ...
What is the current status of trial NCT00688259?
This trial is currently completed. It is a NA study. The enrollment target is 122 participants. The study started on 2009-04. Estimated completion is 2015-01.
What conditions does trial NCT00688259 study?
This clinical trial studies the following conditions: Schizophrenia, Schizoaffective Disorder.
What interventions are being tested in trial NCT00688259?
The interventions under investigation include: Supportive Therapy (ST) (BEHAVIORAL), Cognitive Behavioral Therapy for Psychosis (CBTp) (BEHAVIORAL).
Who is sponsoring clinical trial NCT00688259?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00688259 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Schizophrenia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00688259's enrollment target sits among peer trials
122 118th of 315 higher than 197 of 315 other Schizophrenia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Schizophrenia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Taking Action for College Students
RECRUITING · NA
-
Enhancing Prefrontal Oscillations and Working Memory in Early-course Schizophrenia
RECRUITING · NA
-
Getting Out of the House: Using Behavioral Activation to Increase Community Participation
RECRUITING · NA
-
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 1)
RECRUITING · NA
-
Cerebellar Modulation of Cognition in Psychosis
RECRUITING · NA
-
TMS for Inhibition Enhancement in Schizophrenia
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03363373 · 122 participants · Phase 2
Naxitamab for High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrow
- NCT03463954 · 122 participants · NA
Confirmatory Clinical Evaluation of Novilase® Laser Therapy for Focal Destruction of Malignant Breast Tumors
- NCT04503265 · 122 participants · Phase 1
A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies
- NCT04700527 · 122 participants · Phase 1
The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia