VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 16 of 34

COMPLETED NA

COPD Access to Pulmonary Rehabilitation Intervention

NCT03794921

COMPLETED NA

Evaluation of the National Randomized Proton Pump Inhibitor De-prescribing (RaPPID) Program

NCT03719170

TERMINATED Phase 4

Predicting SSRI Efficacy in Veterans With PTSD

NCT04183205

COMPLETED NA

Written Exposure Therapy Versus Prolonged Exposure: a Non-inferiority Trial

NCT03962504

COMPLETED NA

Models of Primary Osteoporosis Screening in Male Veterans

NCT04079868

COMPLETED NA

Mindful Action for Pain

NCT03800654

COMPLETED

Preventing Levodopa Induced Dyskinesia in Parkinson's Disease With HMG-CoA Reductase Inhibitors

NCT04064294

COMPLETED NA

A Novel Posttraumatic Stress Disorder Treatment for Veterans With Moral Injury

NCT03764033

COMPLETED

Does Walking Performance Improve When Veterans With Leg Amputations Are Given Visual Feedback?

NCT03974945

COMPLETED Phase 1

CONTROL Walking Study

NCT03790657

COMPLETED Phase 1

FMT in Cirrhosis and Hepatic Encephalopathy

NCT03796598

COMPLETED NA

Improving Diabetes Care Through Effective Personalized Patient Portal Interactions

NCT02953262

COMPLETED NA

Pioglitazone for the Treatment of Alcohol Use Disorder

NCT03864146

COMPLETED NA

Mindful Self Compassion for Combat Deployed Veterans With Moral Injury and Co-occurring PTSD-SUD

NCT03681288

COMPLETED NA

A Pragmatic Trial To Determine the Benefit of Exercise Incentives and Corticosteroid Injections in Osteoarthritis of the Knee

NCT03835910

TERMINATED Phase 2

Neurosteroids in PTSD - Biomarkers to Therapeutics

NCT03491007

COMPLETED NA

Reproductive Life Planning for Women With Mental Illness

NCT03969589

COMPLETED NA

Aerobic Exercise in Parkinson's Disease

NCT03808675

COMPLETED NA

Pilot Study of Annie Text Messaging for Depression Treatment Adherence

NCT03930849

COMPLETED NA

Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop

NCT03868930

COMPLETED NA

Narrative Exposure Therapy (NET)

NCT03777553

COMPLETED NA

Improving Outcomes for Emergency Department Patients With Alcohol Problems

NCT03536546

COMPLETED

Cognition and Psychotherapy in PTSD

NCT03641924

COMPLETED NA

Optimizing Psychotherapy for Older Veterans With Chronic Pain

NCT03918642

COMPLETED NA

Yoga and Physical Activity for Veterans

NCT03509909

COMPLETED

HCV and Co-morbid Alcohol Use Disorders: A Translational Investigation of Antiviral Therapy Outcomes on CNS Function

NCT03902366

COMPLETED NA

Teaching Obesity Treatment Options to Adult Learners Trial

NCT03856320

COMPLETED

Teledermatology Mobile App: Patient Facing

NCT03241589

COMPLETED NA

Promoting Smoking Cessation in Lung Cancer Screening Through Proactive Treatment

NCT03612804

COMPLETED Phase 2

Neurosteroids for PTSD in Veterans

NCT03799562

COMPLETED NA

Evaluate Health Coaching Support in Technology-based Interventions for Meeting Health Goals

NCT04021472

COMPLETED NA

Assessing the Effect of Distance Learning Vocational Rehabilitation on Employment Outcomes of Veterans With Psychiatric Illness and Histories of Legal Convictions

NCT03331354

COMPLETED Phase 2

Pilot Study of the Effect of Ibudilast on Neuroinflammation in Methamphetamine Users

NCT03341078

COMPLETED NA

Exercise Training to Improve Cognitive Function

NCT03824639

COMPLETED

Optimizing Prosthetic and Bicycle Fit for Veterans With Transtibial Amputations

NCT03828331

COMPLETED NA

Reducing Anxiety and Stress in Primary Care Patients

NCT03794089

COMPLETED NA

Thriving in the Midst of Moral Pain: The Acceptability and Feasibility of Acceptance and Commitment Therapy for Moral Injury (ACT-MI) Among Warzone Veterans

NCT03760731

COMPLETED NA

Neuromodulation for Exercise Adherence

NCT03733041

COMPLETED NA

Improving Function Through Primary Care Treatment of Posttraumatic Stress Disorder (PTSD)

NCT03581981

COMPLETED NA

Improving Outcomes for Older Veterans With Chronic Back Pain and Depression

NCT03896035

COMPLETED NA

Social and Financial Incentives to Increase Physical Activity Among Overweight and Obese Veterans

NCT03563027

COMPLETED NA

Hearing Impairment, Strategies, and Outcomes in Emergency Departments

NCT03594500

COMPLETED NA

Improving Transplant Medication Safety Through A Technology and Pharmacist Intervention

NCT03860818

COMPLETED NA

Assessment and Treatment of Cognitive Functioning Deficits in Veterans With PTSD

NCT03696225

COMPLETED NA

Effect of Aging on Cortical Excitability and Motor Learning

NCT03750903

COMPLETED NA

Parenting Strength At Home- Parents Pilot

NCT03403153

COMPLETED NA

Protective Stepping in People With MS

NCT03551665

COMPLETED NA

RCT of Brief CBT-I in Primary Care Veterans With Suicidal Thoughts

NCT03603717

COMPLETED

Postural Stability in Cervical Spinal Myelopathy

NCT03810781

COMPLETED NA

Spinal Plasticity to Enhance Motor Retraining After Stroke

NCT03645122

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.