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NCT03722017 · ClinicalTrials.gov registry record · NA
Drug Reduction in Older Patients: The DROP Trial
A NA study of Frail Elderly and Geriatric Assessment, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 260
- Enrollment target
- 1
- Study location
NCT03722017: Completed NA study of Frail Elderly and Geriatric Assessment, sponsored by VA Office of Research and Development.
NCT03722017 is a NA study of Frail Elderly and Geriatric Assessment that has completed, run by VA Office of Research and Development. The registered enrollment target is 260 participants, above the 160-participant average among 8 other Frail Elderly trials with a reported enrollment target (63% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03722017, a NA study of Frail Elderly and Geriatric Assessment, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 260 participants
- Enrollment target
- 1
- Study location
Study Summary
Project Objectives: The proposed randomized, controlled trial will evaluate the effects of procedures to reduce medications among hospitalized older Veterans discharged to nursing homes using an hybrid study design to inform future efforts to spread it across VA. Project Background/Rationale: Patients discharged to nursing homes for short stays represent the largest group of Medicare beneficiaries discharged to post-hospital services and are a particularly high risk group for loss of independence and other poor clinical outcomes. This investigative team recently completed a VA-funded Quality Improvement Award and a Centers for Medicare and Medicaid Services (CMS) Innovation Award, both of which provide strong results related to the occurrence of polypharmacy and the relationship between polypharmacy and geriatric syndromes (e.g., medications associated with falls) in this patient population. Based on these data, the investigators developed and pilot-tested a patient-centered deprescribing set of procedures combined with standardized questions for eight geriatric syndromes to be implemented in the hospital and monitored during the nursing home stay. Project Methods: The investigators propose an innovative hybrid study design that will be conducted in one VA hospital. The goal of the proposed DROP intervention is to safely deprescribe medications, as defined by reducing doses or stopping medications, based on a combination of clinical criteria and Veteran preferences. This randomized, controlled trial conducted over three years will evaluate the effects of this hospital-based intervention on medication use, geriatric syndromes, and health status across Veterans' care transitions from the hospital to nursing home to home to include a 90-day follow-up period after leaving the nursing home. The hypothesis is that reducing medications for older Veterans will favorably impact geriatric syndromes. Additionally, the investigators aim to understand Veteran, both VA and non-
Primary Outcome
The number of medications a participant is taking. This includes all prescribed and over-the-counter medications and both scheduled and as-needed (PRN) medications.
Conditions Studied
Interventions
- OTHER Deprescribing intervention
Study Locations (1)
Tennessee
- Tennessee Valley Healthcare System Nashville Campus, Nashville, TN - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 260 participants |
| Start Date | 2019-10-07 |
| Est. Completion | 2023-03-31 |
| Phase | NA |
What the finished NCT03722017 record still lists
NCT03722017 is an interventional study that assigns participants to a tested intervention. The registered 260 participants enrollment target is mid-sized for trials with a published cap, above the 160-participant average among 8 other Frail Elderly trials with a reported enrollment target (63% higher).
The record links to 4 conditions, with Frail Elderly appearing as the primary indexed condition, and to 1 intervention - of which Deprescribing intervention is the first listed.
NCT03722017 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT03722017 about?
NCT03722017 is a clinical study titled "Drug Reduction in Older Patients: The DROP Trial". Project Objectives: The proposed randomized, controlled trial will evaluate the effects of procedures to reduce medications among hospitalized older Veterans discharged to nursing homes using an hybrid study design to inform future efforts to spread it across VA. Project Background/Rationale: Patie...
What is the current status of trial NCT03722017?
This trial is currently completed. It is a NA study. The enrollment target is 260 participants. The study started on 2019-10-07. Estimated completion is 2023-03-31.
What conditions does trial NCT03722017 study?
This clinical trial studies the following conditions: Frail Elderly, Geriatric Assessment, Patient Centered Care, Skilled Nursing Facilities.
What interventions are being tested in trial NCT03722017?
The interventions under investigation include: Deprescribing intervention (OTHER).
Who is sponsoring clinical trial NCT03722017?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03722017 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03722017's enrollment target sits among peer trials
260 3rd of 8 higher than 6 of 8 other Frail Elderly trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Frail Elderly trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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