VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 12 of 34

COMPLETED NA

Transcutaneous Stimulation in Spinal Cord Injury

NCT05180227

COMPLETED NA

Treatment, Pain, and Opioids

NCT05363176

COMPLETED NA

Promoting Benzodiazepine Cessation Through an Electronically-delivered Patient Self-management Intervention

NCT04572750

COMPLETED NA

Functional and Cognitive Rehabilitation of Hoarding Disorder

NCT04697849

COMPLETED Phase 2

Targeting the Endothelial Glycocalyx to Enhance Vascular Function and Exercise-Induced Vascular Adaptations in Type 2 Diabetes

NCT05205005

COMPLETED

COVID-19 Observational Research Collaboratory

NCT05394025

COMPLETED NA

Developing a Team-Delivered Intervention for Smoking and Hazardous Drinking for Primary Care Veterans With Cardiovascular Diseases

NCT05275582

COMPLETED Phase 1

Non-invasive Vagal Nerve Stimulation in Alcohol Use Disorder

NCT05226130

COMPLETED Phase 4

Tobacco Cessation Treatment Preferences Among Veteran Smokers

NCT05277207

COMPLETED NA

Unmet Social Needs Study

NCT04977583

COMPLETED NA

Implementing a Skills-Based Caregiver Training Program (Caregivers FIRST): Function QUERI 2.0

NCT05319535

COMPLETED NA

Initial Testing of Whole Health STEPS

NCT04390451

COMPLETED NA

Evaluation of Vision-Guided Shared Control for Assistive Robotics Manipulators

NCT04323449

COMPLETED NA

Developing and Testing a COVID-19 Vaccination Acceptance Intervention

NCT05027464

COMPLETED NA

Pragmatic Obstructive Sleep Apnea Weight Loss Trial Assessing Effectiveness and Reach

NCT05104450

COMPLETED Early Phase 1

Sensory Augmentation Methods in Stroke

NCT03988400

COMPLETED Phase 1

An Adaptive Walking Intervention to Manage Chronic Pain in Veterans With Opioid Use Disorder Engaged in Opioid Agonist Treatment

NCT05051644

COMPLETED NA

Effect of Expanding (Gloving) Barrier Precautions for Reducing Clostridium Difficile Acquisition (and Infection) in VA

NCT04036058

COMPLETED NA

Developing an Online Therapeutic Intervention for Chronic Pain in Veterans

NCT03655132

COMPLETED NA

Multiphase Optimization Trial of Incentives for Veterans to Encourage Walking

NCT04518943

COMPLETED NA

TARDIS - Photo Elicitation and Intervention

NCT06972251

COMPLETED NA

Nutrition, Inflammation and Insulin Resistance in End-Stage Renal Disease

NCT04067752

COMPLETED

Lifestyle and Cardiometabolic Risk in Post-9/11 Veterans

NCT04911153

COMPLETED NA

ACTIVE: Activity Therapy to Increase Veteran Engagement

NCT04976621

COMPLETED NA

Internet-based Cognitive-behavioral Treatment for Insomnia in COPD Patients Undergoing Pulmonary Rehabilitation

NCT04700098

COMPLETED NA

Customized Employment for Veterans With Spinal Cord Injury

NCT04832802

COMPLETED NA

Neurofeedback to Aid Vets' Memory

NCT04446481

TERMINATED NA

Reducing Suicide Risk in Older Veterans Using Problem Solving Therapy

NCT04763330

COMPLETED Phase 1

Methylphenidate for Ptsd and Stroke Veterans

NCT04885257

COMPLETED Phase 1

TMS and Exercise for Post-stroke Pain

NCT04672044

TERMINATED NA

A Randomized Control Trial Treating Depression With Yoga and Coherent Breathing Versus Walking in Veterans

NCT03489122

COMPLETED NA

Addressing Insufficient PAP Use in Older Veterans

NCT04868682

COMPLETED NA

SleepSMART for Veterans With MCI and Insomnia

NCT05016960

COMPLETED NA

A Novel Cognitive Remediation Intervention Targeting Poor Decision-making and Depression in Veterans at High Risk for Suicide: A Safe, Telehealth Approach During the COVID-19 Pandemic

NCT04952532

COMPLETED

Dual-tasking for Individuals With Lower Limb Amputation: Exploring the Relationship to Falls and Instrumental Activities of Daily Living

NCT05119192

COMPLETED NA

Pilot Trial of Mobile Mantram Delivery

NCT05998967

COMPLETED NA

Developing a Mobile Intervention to Reduce Suicidal Cognitions in Veterans

NCT04881903

COMPLETED NA

An Engineering-Based Balance Assessment and Training Platform

NCT03994770

COMPLETED

A Balanced Assessment and Training Protocol (BATP) to Address Balance Disorders in Older and Neurologically Disabled Veterans

NCT04359888

COMPLETED NA

Improving Depression Management

NCT05050227

COMPLETED NA

Engaging Medically Complex Veterans in Tele-Rehabilitation Using a Biobehavioral Approach

NCT04942613

COMPLETED NA

Mobile Self-Tracking of Mental Health

NCT05023252

TERMINATED NA

Expanding Access to Comprehensive Geriatrics Care Via Telehealth

NCT05166603

COMPLETED NA

Exercise Mode and Acute Bone Resorption

NCT04815824

TERMINATED Phase 2

Nitrous Oxide for PTSD

NCT04378426

COMPLETED NA

Assessing Open Access Audio

NCT04452331

COMPLETED Phase 2

Effects of Electrical Stimulation and Vitamin D Supplementation on Bone Health Following Spinal Cord Injury.

NCT05008484

COMPLETED NA

Brief Cognitive Behavioral Therapy for Chronic Pain to Improve Functioning Among Veterans

NCT04724694

COMPLETED NA

Improving Walking in Peripheral Artery Disease

NCT05103280

COMPLETED NA

Plantarflexor PAS - Stroke

NCT04515407

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.